Biochemical changes and gene expression following traumatic brain injury: Role of spreading depression

Expression of a set of growth-related immediate early genes in BALB/c 3T3 cells: coordinate regulation with c-fos or c-myc.

1987 • 888 citations

Effect of protein synthesis inhibitors on growth factor activation of c-fos, c-myc, and actin gene transcription.

1986 • 548 citations

Correlation between periinfarct DC shifts and ischaemic neuronal damage in rat

1993 • 400 citations

Protein synthesis inhibitors differentially superinduce c-fos and c-jun by three distinct mechanisms: lack of evidence for labile repressors.

1992 • 297 citations

Regional Changes in Interstitial K⁺and Ca²⁺Levels following Cortical Compression Contusion Trauma in Rats

1993 • 275 citations

Posttranscriptional regulation of c-fos mRNA expression

1987 • 215 citations

Lactate accumulation following concussive brain injury: the role of ionic fluxes induced by excitatory amino acids

1995 • 187 citations

Basic mechanisms of traumatic brain damage

1993 • 158 citations

Secondary injury and acidosis.

1992 • 157 citations

Production and clearance of lactate from brain tissue, cerebrospinal fluid, and serum following experimental brain injury

1988 • 147 citations

Differential Expression of the Immediate Early Genes c-Fos, c-Jun, JunB, andNGFI-B in the Rat Brain following Transient Forebrain Ischemia

1994 • 128 citations

Effect of THAM upon outcome in severe head injury: a randomized prospective clinical trial

1993 • 121 citations

Traumatic Brain Injury in the Rat: Alterations in Brain Lactate and pH as Characterized by ¹H and ³¹P Nuclear Magnetic Resonance

1987 • 120 citations

Uncoupling of local cerebral glucose metabolism and blood flow after acute fluid-percussion injury in rats

1997 • 106 citations

Widespread Hemodynamic Depression and Focal Platelet Accumulation after Fluid Percussion Brain Injury: A Double-Label Autoradiographic Study in Rats

1996 • 99 citations

Cerebral energy metabolism following fluid-percussion brain injury in cats

1988 • 86 citations

Increased expression of c-fos mRNA and AP-1 transcription factors after cortical impact injury in rats

1994 • 84 citations

Regional Levels of Lactate and Norepinephrine After Experimental Brain Injury

1994 • 80 citations

Regional Induction of c-Fosand Heat Shock Protein-72 mRNA following Fluid-Percussion Brain Injury in the Rat

1995 • 72 citations

Impact Acceleration-Induced Severe Diffuse Axonal Injury in Rats: Characterization of Phosphate Metabolism and Neurologic Outcome

1995 • 67 citations

Time Course of Changes in Lactate and Free Fatty Acids after Experimental Brain Injury and Relationship to Morphologic Damage

1997 • 67 citations

Monitoring the temporal and spatial activation pattern of astrocytes in focal cerebral ischemia using in situ hybridization to GFAP mRNA: comparison withsgp-2 andhsp70 mRNA and the effect of glutamate receptor antagonists

1996 • 63 citations

Traumatic Brain Tissue Acidosis: Experimental and Clinical Studies

1993 • 38 citations

Expression of c-fos, junB, c-jun, MKP-1 AND hsp72 following traumatic neocortical lesions in rats—relation to spreading depression

1999 • 37 citations

Inhibition of Protein Synthesis During Repetitive Cortical Spreading Depression

1993 • 33 citations

Transient forebrain ischemia induces an immediate-early gene encoding the mitogen-activated protein kinase phosphatase 3CH134 in the adult rat brain

1995 • 30 citations

Expression of c-fos and hsp70 mRNA after traumatic brain injury in transgenic mice overexpressing CuZn-superoxide dismutase

1995 • 29 citations

Effects of a traumatic neocortical lesion on cerebral metabolism and gene expression of rats

1998 • 18 citations

31P-Magnetic Resonance Spectroscopic Study on the Effect of Glycerol on Cold-Induced Brain Edema

1994 • 5 citations