Inhaled NO as a viable antiadhesive therapy for ischemia/reperfusion injury of distal microvascular beds.

Nitric oxide decreases cytokine-induced endothelial activation. Nitric oxide selectively reduces endothelial expression of adhesion molecules and proinflammatory cytokines.

1995 • 1,762 citations

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

1996 • 1,604 citations

S-nitrosylation of proteins with nitric oxide: synthesis and characterization of biologically active compounds.

1992 • 1,454 citations

Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn

1997 • 787 citations

Diminished basal nitric oxide release after myocardial ischemia and reperfusion promotes neutrophil adherence to coronary endothelium.

1993 • 490 citations

Modulation of ischemia/reperfusion-induced microvascular dysfunction by nitric oxide.

1994 • 396 citations

Neutrophil accumulation on activated, surface-adherent platelets in flow is mediated by interaction of Mac-1 with fibrinogen bound to alphaIIbbeta3 and stimulated by platelet-activating factor.

1997 • 372 citations

Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium

1990 • 370 citations

Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia

1991 • 351 citations

Leukocyte-endothelium adhesion: Microhemodynamics in mesentery of the cat

1987 • 347 citations

Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils.

1994 • 334 citations

Fluid Flow Inhibits Endothelial Adhesiveness

1996 • 300 citations

NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties.

1993 • 294 citations

Therapeutic potential of inhibiting leukocyte rolling in ischemia/reperfusion.

1995 • 256 citations

Selectin-mediated rolling of neutrophils on immobilized platelets

1993 • 236 citations

Role of platelet-activating factor in ischemia/reperfusion-induced leukocyte adherence

1990 • 226 citations

Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion

1994 • 216 citations

Nitric oxide donors reduce the rise in reperfusion-induced intestinal mucosal permeability

1993 • 154 citations

Microvascular Responses to Inhibition of Nitric Oxide Production

1995 • 148 citations

Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia

1994 • 140 citations

A Juxtacrine Mechanism for Neutrophil Adhesion on Platelets Involves Platelet-Activating Factor and a Selectin-Dependent Activation Process

1998 • 139 citations

The role of nitric oxide as an endogenous regulator of platelet and neutrophil activation within the pulmonary circulation of the rabbit

1991 • 136 citations

Differential regulation of the constitutive and inducible nitric oxide synthase mRNA by lipopolysacchride treatment in vivo in the rat

1996 • 134 citations

Nitric Oxide Inhibits Numerous Features of Mast Cell–Induced Inflammation

1996 • 119 citations

Chronic Inhalation of Nitric Oxide Inhibits Neointimal Formation After Balloon-Induced Arterial Injury

1996 • 113 citations

Downregulation of Endothelial Constitutive Nitric Oxide Synthase Expression by Lipopolysaccharide

1996 • 106 citations

Leukotriene C₄/D₄Induces P-Selectin and Sialyl Lewis^x–Dependent Alterations in Leukocyte Kinetics In Vivo

1995 • 95 citations

Inhaled Nitric Oxide Increases Coronary Artery Patency After Thrombolysis

1996 • 70 citations

S-nitrosohaemoglobin: a dynamic activity of blood involved in vascular control

1997 • 60 citations

Nitrosyl hemoglobin in blood of normoxic and hypoxic sheep during nitric oxide inhalation

1998 • 51 citations

A new side effect of inhaled nitric oxide in neonates and infants with pulmonary hypertension: Functional impairment of the neutrophil respiratory burst

1996 • 45 citations

Excess nitric oxide does not cause cellular, vascular, or mucosal dysfunction in the cat small intestine

1995 • 41 citations

The pharmacology of inhaled nitric oxide.

1995 • 35 citations

Effect of venous shear stress on CD18-mediated neutrophil adhesion to cultured endothelium

1990 • 34 citations

Delayed Administration of Inhaled Nitric Oxide Preserves Alveolar-Capillary Membrane Integrity in Porcine Gram-negative Sepsis

1997 • 31 citations

Cerebral hemodynamics and distribution of left ventricular output during inhalation of nitric oxide

1995 • 29 citations

Endogenous but not exogenous nitric oxide decreases TNF-alpha-induced leukocyte rolling

1997 • 22 citations

Selectin-mediated rolling of neutrophils on immobilized platelets

1993 • 17 citations

Inhaled Nitric Oxide in Anesthesia and Critical Care Medicine

1995 • 17 citations

Inhaled Nitric Oxide in Anesthesia and Critical Care Medicine

1994 • 16 citations

Leukotriene C4/D4 Induces P-Selectin and Sialyl Lewisx–Dependent Alterations in Leukocyte Kinetics In Vivo

1995 • 3 citations

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