Nitric Oxide Inhibits Numerous Features of Mast Cell–Induced Inflammation

Leukocytes roll on a selectin at physiologic flow rates: Distinction from and prerequisite for adhesion through integrins

1991 • 2,195 citations

Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein.

1984 • 1,249 citations

New Concepts about the Mast Cell

1993 • 1,009 citations

Two-step model of leukocyte-endothelial cell interaction in inflammation: distinct roles for LECAM-1 and the leukocyte beta 2 integrins in vivo.

1991 • 977 citations

Complexes of ^.NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects

1991 • 724 citations

Production of hydroxyl radicals from the simultaneous generation of superoxide and nitric oxide

1992 • 702 citations

Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140

1989 • 653 citations

Oxygen radicals induce human endothelial cells to express GMP-140 and bind neutrophils.

1991 • 605 citations

A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo

1987 • 525 citations

Lectin-like cell adhesion molecule 1 mediates leukocyte rolling in mesenteric venules in vivo

1991 • 473 citations

Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat.

1990 • 471 citations

Mast cell heterogeneity: effects of neuroenteric peptides on histamine release.

1985 • 440 citations

Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion.

1988 • 421 citations

Modulation of ischemia/reperfusion-induced microvascular dysfunction by nitric oxide.

1994 • 396 citations

Leukocyte-endothelium adhesion: Microhemodynamics in mesentery of the cat

1987 • 347 citations

Intracellular oxidative stress induced by nitric oxide synthesis inhibition increases endothelial cell adhesion to neutrophils.

1994 • 334 citations

Nitric oxide prevents leukocyte adherence: role of superoxide

1993 • 331 citations

Nitric oxide synthesis inhibition induces leukocyte adhesion via superoxide and mast cells

1993 • 325 citations

The role of L-arginine in ameliorating reperfusion injury after myocardial ischemia in the cat.

1992 • 323 citations

Gastrointestinal food hypersensitivity: Basic mechanisms of pathophysiology

1992 • 317 citations

Recruitment of neutrophils during IgE-dependent cutaneous late phase reactions in the mouse is mast cell-dependent. Partial inhibition of the reaction with antiserum against tumor necrosis factor-alpha.

1991 • 298 citations

Inhibition of endothelial-derived nitric oxide promotes P-selectin expression and actions in the rat microcirculation

1994 • 283 citations

E-selectin supports neutrophil rolling in vitro under conditions of flow.

1993 • 273 citations

Role of CD11/CD18 in shear rate-dependent leukocyte-endothelial cell interactions in cat mesenteric venules.

1991 • 258 citations

Histamine induces leukocyte rolling in post-capillary venules. A P-selectin-mediated event.

1994 • 239 citations

The late phase of the immunoglobulin E-mediated reaction: a link between anaphylaxis and common allergic disease?

1982 • 223 citations

Cardioprotective effects of authentic nitric oxide in myocardial ischemia with reperfusion

1991 • 217 citations

Nitric oxide attenuates leukocyte-endothelial interaction via P-selectin in splanchnic ischemia-reperfusion

1994 • 216 citations

Nitric Oxide Donors Increase Blood Flow and Reduce Brain Damage in Focal Ischemia: Evidence That Nitric Oxide is Beneficial in the Early Stages of Cerebral Ischemia

1994 • 206 citations

Nitric oxide synthesis inhibition increases epithelial permeability via mast cells

1994 • 202 citations

Mechanisms underlying acute mast cell-induced leukocyte rolling and adhesion in vivo.

1995 • 164 citations

Decreased basal nitric oxide release in hypercholesterolemia increases neutrophil adherence to rabbit coronary artery endothelium.

1993 • 155 citations

Nitric oxide donors reduce the rise in reperfusion-induced intestinal mucosal permeability

1993 • 154 citations

Regulation of intracellular free Mg2+ and contraction in single adult mammalian cardiac myocytes

1994 • 152 citations

Role of H1 receptors and P-selectin in histamine-induced leukocyte rolling and adhesion in postcapillary venules.

1994 • 151 citations

Microvascular Responses to Inhibition of Nitric Oxide Production

1995 • 148 citations

L-arginine decreases infarct size caused by middle cerebral arterial occlusion in SHR

1992 • 123 citations

The association of mast cells and atherosclerosis: A morphologic study of early atherosclerotic lesions in young people

1994 • 118 citations

Microvascular oxidative stress preceding leukocyte activation elicited by in vivo nitric oxide suppression

1994 • 107 citations

The biologic activity of mast cell granules. I. Elicitation of inflammatory responses in rat skin.

1980 • 104 citations

Augmentation of reverse arthus reaction by mast cells in mice.

1991 • 97 citations

Modulation of rat mast cell reactivity by IL-1 beta. Divergent effects on nitric oxide and platelet-activating factor release.

1993 • 95 citations

Reductions in physiologic shear rates lead to CD11/CD18-dependent, selectin-independent leukocyte rolling in vivo

1994 • 94 citations

The mast cell and synovial inflammation

1984 • 85 citations

Nitric Oxide

1991 • 83 citations

Mast cells contribute to ischemia-reperfusion-induced granulocyte infiltration and intestinal dysfunction

1994 • 82 citations

Anoxia-reoxygenation-induced, neutrophil-mediated endothelial cell injury: role of elastase

1990 • 80 citations

Effects of human neutrophil elastase (HNE) on neutrophil function in vitro and in inflamed microvessels

1993 • 77 citations

Acute reoxygenation injury in the isolated rat heart: role of resident cardiac mast cells.

1988 • 77 citations

Human Synovial Mast Cell Involvement in Rheumatoid Arthritis and Osteoarthritis. Relationship to Disease Type, Clinical Activity, and Antirheumatic Therapy

1991 • 77 citations

Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine

1991 • 75 citations

Nitric Oxide

1991 • 73 citations

Ischemia/Reperfusion‐Induced Granulocyte Influx is a Multistep Process Mediated by Mast Cells

1994 • 63 citations

Xanthine oxidase inhibition attenuates ischemic-reperfusion lung injury

1988 • 58 citations

Nitrovasodilators inhibit thrombin-induced platelet-activating factor synthesis in human endothelial cells

1992 • 52 citations

Lung Mast Cells Increase in Number and Degranulate during Pulmonary Artery Occlusion/Reperfusion Injury in Dogs

1993 • 52 citations

Dermal and Epidermal Involvement in the Evolution of Acute Eruptive Guttate Psoriasis vulgaris

1984 • 46 citations

Production of Platelet-activating Factor, a Biologically Active Lipid, by Vascular Endothelial Cells

1987 • 25 citations

Nitric oxide modulates cardiac and mast cell anaphylaxis

1994 • 22 citations

Effect of 3-morpholinosydnonimine (SIN-1) and NG-nitro-l-arginine (NNA) on isolated perfused anaphylactic guinea-pig hearts

1992 • 16 citations

Prevention of ischemia-reperfusion injury by the allergy drug lodoxamide tromethamine

1991 • 10 citations

Mechanisms of inflammation and their therapeutic implications in the asthmatic patient.

1992 • 9 citations