The effects of cannabinoids on the brain

Isolation and Structure of a Brain Constituent That Binds to the Cannabinoid Receptor

1992 • 5,504 citations

Molecular characterization of a peripheral receptor for cannabinoids

1993 • 4,950 citations

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1990 • 4,933 citations

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

1995 • 2,837 citations

Determination and characterization of a cannabinoid receptor in rat brain.

1988 • 2,339 citations

Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish

1964 • 2,296 citations

Cannabinoid receptor localization in brain.

1990 • 2,248 citations

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

1991 • 2,139 citations

Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

1996 • 2,079 citations

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

1994 • 1,743 citations

Expression of Central and Peripheral Cannabinoid Receptors in Human Immune Tissues and Leukocyte Subpopulations

1995 • 1,689 citations

Formation and inactivation of endogenous cannabinoid anandamide in central neurons

1994 • 1,564 citations

Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system

1998 • 1,549 citations

A second endogenous cannabinoid that modulates long-term potentiation

1997 • 1,474 citations

Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common µ ₁ Opioid Receptor Mechanism

1997 • 1,078 citations

Control of pain initiation by endogenous cannabinoids

1998 • 1,044 citations

Cannabinoid receptors in the human brain: a detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain

1997 • 992 citations

Roles of N-Type and Q-Type Ca ²⁺ Channels in Supporting Hippocampal Synaptic Transmission

1994 • 964 citations

Neuroanatomy of the Pain System and of the Pathways That Modulate Pain

1997 • 882 citations

Functional characteristics of the midbrain periaqueductal gray

1995 • 855 citations

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

1995 • 838 citations

Functional Role of High-Affinity Anandamide Transport, as Revealed by Selective Inhibition

1997 • 806 citations

Endogenous opioid systems and alcohol addiction

1997 • 751 citations

Different types of calcium channels mediate central synaptic transmission

1993 • 743 citations

Enzymatic synthesis and degradation of anandamide, a cannabinoid receptor agonist

1993 • 695 citations

Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.

1992 • 694 citations

SR 144528, the first potent and selective antagonist of the CB2 cannabinoid receptor.

1998 • 679 citations

Molecular cloning of a human cannabinoid receptor which is also expressed in testis

1991 • 679 citations

Distribution of neuronal cannabinoid receptor in the adult rat brain: A comparative receptor binding radioautography and in situ hybridization histochemistry

1992 • 654 citations

Localization of cannabinoid receptor mRNA in rat brain

1993 • 623 citations

Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor

1995 • 619 citations

Neural Mechanisms of Drug Reinforcementa

1992 • 610 citations

Cannabinoid Receptor Agonists Inhibit Glutamatergic Synaptic Transmission in Rat Hippocampal Cultures

1996 • 604 citations

Cannabinoids Inhibit N- and P/Q-Type Calcium Channels in Cultured Rat Hippocampal Neurons

1997 • 546 citations

Chronic Administration of Cannabidiol to Healthy Volunteers and Epileptic Patients

1980 • 538 citations

Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1

1995 • 535 citations

Calcium control of transmitter release at a cerebellar synapse

1995 • 532 citations

Neuronal localization of cannabinoid receptors in the basal ganglia of the rat

1991 • 515 citations

Health aspects of cannabis

1987 • 495 citations

Activation of Corticotropin-Releasing Factor in the Limbic System During Cannabinoid Withdrawal

1997 • 494 citations

The residual cognitive effects of heavy marijuana use in college students

1996 • 480 citations

Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction.

1993 • 469 citations

In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding.

1995 • 450 citations

Involvement of Gi in the inhibition of adenylate cyclase by cannabimimetic drugs.

1986 • 446 citations

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

1991 • 403 citations

The pharmacological activity of anandamide, a putative endogenous cannabinoid, in mice.

1994 • 383 citations

Cannabinoid pharmacology

1987 • 368 citations

Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra

1997 • 366 citations

Cannabinoids activate mesolimbic dopamine neurons by an action on cannabinoid CB1 receptors

1998 • 363 citations

Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells

1993 • 356 citations

Inhibition by anandamide of gap junctions and intercellular calcium signalling in striatal astrocytes

1995 • 353 citations

Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes.

1984 • 353 citations

Drug Addiction: The Yin and Yang of Hedonic Homeostasis

1996 • 345 citations

Cannabinoid Receptors CB1 and CB2: A Characterization of Expression and Adenylate Cyclase Modulation within the Immune System

1997 • 345 citations

Effects of Dronabinol on anorexia and disturbed behavior in patients with Alzheimer's disease

1997 • 337 citations

Isolation and measurement of the endogenous cannabinoid receptor agonist, anandamide, in brain and peripheral tissues of human and rat

1996 • 334 citations

Δ9-Tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis

1990 • 331 citations

Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB¹ receptors on peripheral sympathetic nerves

1996 • 329 citations

An Amino-terminal Variant of the Central Cannabinoid Receptor Resulting from Alternative Splicing

1995 • 321 citations

Partial Purification and Characterization of the Porcine Brain Enzyme Hydrolyzing and Synthesizing Anandamide

1995 • 305 citations

Anandamide, a Brain Endogenous Compound, Interacts Specifically with Cannabinoid Receptors and Inhibits Adenylate Cyclase

1993 • 297 citations

Activation of peripheral CB1 cannabinoid receptors in haemorrhagic shock

1997 • 288 citations

Signaling Pathway Associated with Stimulation of CB2 Peripheral Cannabinoid Receptor

1996 • 277 citations

Cannabinoid receptor agonists inhibit Ca current in NG108–15 neuroblastoma cells via a Pertussis toxin‐sensitive mechanism

1992 • 273 citations

Cannabinoid receptor binding and messenger RNA expression in human brain: An in vitro receptor autoradiography and in situ hybridization histochemistry study of normal aged and Alzheimer's brains

1994 • 269 citations

Hypnotic and Antiepileptic Effects of Cannabidiol

1981 • 267 citations

Cannabinoid agonists stimulate both receptor- and non-receptor-mediated signal transduction pathways in cells transfected with and expressing cannabinoid receptor clones.

1992 • 266 citations

SR141716A is an inverse agonist at the human cannabinoid CB1 receptor

1997 • 261 citations

A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques

1991 • 260 citations

Investigation of brain sites mediating cannabinoid-induced antinociception in rats: evidence supporting periaqueductal gray involvement.

1996 • 255 citations

Role of MAP kinase in neurons

1998 • 250 citations

Cellular effects of cannabinoids.

1986 • 248 citations

Cannabinoid inhibition of adenylate cyclase. Biochemistry of the response in neuroblastoma cell membranes.

1985 • 248 citations

Neurobiology of marijuana abuse

1992 • 246 citations

Animal models of intractable epilepsy

1997 • 245 citations

Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation.

1992 • 243 citations

Effects of delta-9-tetrahydrocannabinol on delayed match to sample performance in rats: alterations in short-term memory associated with changes in task specific firing of hippocampal cells.

1993 • 239 citations

Hippocampal neurotoxicity of Delta9-tetrahydrocannabinol.

1998 • 237 citations

Anandamide, an endogenous ligand of the cannabinoid receptor, induces hypomotility and hypothermia in vivo in rodents

1993 • 237 citations

Occurrence and postmortem generation of anandamide and other long‐chain N‐acylethanolamines in mammalian brain

1995 • 233 citations

Δ9-Tetrahydrocannabinol excites rat VTA dopamine neurons through activation of cannabinoid CB1 but not opioid receptors

1997 • 227 citations

Loss of cannabinoid receptors in the substantia nigra in huntington's disease

1993 • 227 citations

Cannabinoids decrease excitatory synaptic transmission and impair long‐term depression in rat cerebellar Purkinje cells

1998 • 227 citations

LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation.

1998 • 223 citations

Enzymatic synthesis of anandamide, an endogenous ligand for the cannabinoid receptor, by brain membranes.

1994 • 221 citations

Hippocampal Neurotoxicity of Δ⁹-Tetrahydrocannabinol

1998 • 217 citations

Differential impairments of selective attention due to frequency and duration of cannabis use

1995 • 214 citations

Spinal and supraspinal components of cannabinoid-induced antinociception.

1991 • 214 citations

Inhibition of GABAergic inhibitory postsynaptic currents by cannabinoids in rat corpus striatum

1998 • 213 citations

Δ9-Tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism

1996 • 213 citations

Transacylase‐Mediated and Phosphodiesterase‐Mediated Synthesis of N‐Arachidonoylethanolamine, an Endogenous Cannabinoid‐Receptor Ligand, in Rat Brain Microsomes

1996 • 209 citations

Cannabinoid Receptors and Modulation of Cyclic AMP Accumulation in the Rat Brain

1990 • 209 citations

Neurochemical Bases of Locomotion and Ethanol Stimulant Effects

1996 • 209 citations

Pharmacological profile of a series of bicyclic cannabinoid analogs: classification as cannabimimetic agents.

1992 • 207 citations

Inhibition of long-term potentiation in rat hippocampal slices by anandamide and WIN55212-2: reversal by SR141716 A, a selective antagonist of CB1 cannabinoid receptors

1995 • 205 citations

Nicotine and food induced dopamine release in the nucleus accumbens of the rat: Putative role of α7 nicotinic receptors in the ventral tegmental area

1998 • 203 citations

The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: connections with anandamide

1998 • 199 citations

Antinociceptive activity of intrathecally administered cannabinoids alone, and in combination with morphine, in mice.

1992 • 197 citations

Cannabinoid-induced hypotension and bradycardia in rats mediated by CB1-like cannabinoid receptors.

1997 • 196 citations

Marijuana, immunity and infection

1998 • 192 citations

Acute and residual effects of alcohol and marijuana, alone and in combination, on mood and performance

1994 • 188 citations

Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase

1995 • 186 citations

Nonpsychotropic cannabinoid acts as a functional N-methyl-D-aspartate receptor blocker.

1989 • 182 citations

Comparative Effects of Alcohol and Marijuana on Mood, Memory, and Performance

1997 • 181 citations

Effects of anandamide on cannabinoid receptors in rat brain membranes

1994 • 179 citations

Selective vulnerability in Huntington's disease: Preferential loss of cannabinoid receptors in lateral globus pallidus

1994 • 176 citations

Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB₁ and CB₂ receptors

1998 • 176 citations

Chronic cannabinoid administration alters cannabinoid receptor binding in rat brain: a quantitative autoradiographic study

1993 • 175 citations

Stimulation of Cannabinoid Receptor CB1 Induces krox-24 Expression in Human Astrocytoma Cells

1995 • 173 citations

Downregulation of rat brain cannabinoid binding sites after chronic Δ9-tetrahydrocannabinol treatment

1994 • 170 citations

Suppression of Noxious Stimulus-Evoked Activity in the Ventral Posterolateral Nucleus of the Thalamus by a Cannabinoid Agonist: Correlation between Electrophysiological and Antinociceptive Effects

1996 • 170 citations

Activation of inwardly rectifying potassium channels (GIRK1) by co-expressed rat brain cannabinoid receptors in Xenopus oocytes

1995 • 168 citations

Cannabinoids modulate potassium current in cultured hippocampal neurons.

1993 • 168 citations

On the Carcinogenicity of Marijuana Smoke

1975 • 163 citations

Localization of mRNA expression and activation of signal transduction mechanisms for cannabinoid receptor in rat brain during fetal development

1998 • 162 citations

Effect of Marihuana on Intraocular and Blood Pressure in Glaucoma

1980 • 160 citations

Role of cyclic AMP in the actions of cannabinoid receptors

1996 • 159 citations

Aminoalkylindole binding in rat cerebellum: selective displacement by natural and synthetic cannabinoids.

1993 • 157 citations

Medicinal Applications of Delta-9-Tetrahydrocannabinol and Marijuana

1997 • 157 citations

Characterization of Δ9-Tetrahydrocannabinol and Anandamide Antinociception in Nonarthritic and Arthritic Rats

1998 • 153 citations

Mechanism of the Hypotensive Action of Anandamide in Anesthetized Rats

1996 • 152 citations

Protein Kinase C Disrupts Cannabinoid Actions by Phosphorylation of the CB1 Cannabinoid Receptor

1998 • 150 citations

Effects of chronic exposure to Δ9-tetrahydrocannabinol on cannabinoid receptor binding and mRNA levels in several rat brain regions

1997 • 147 citations

Some cardiovascular effects of marihuana smoking in normal volunteers

1971 • 146 citations

Cannabinoid CB1 receptor-mediated inhibition of noradrenaline release in the human and guinea-pig hippocampus

1997 • 145 citations

Rat brain cannabinoid receptor modulates N-type Ca2+ channels in a neuronal expression system.

1996 • 143 citations

2‐Arachidonoylglycerol, an endogenous cannabinoid receptor agonist: identification as one of the major species of monoacylglycerols in various rat tissues, and evidence for its generation through Ca²⁺‐dependent and ‐independent mechanisms

1998 • 143 citations

The cannabinoid agonist Win55,212-2 inhibits calcium channels by receptor-mediated and direct pathways in cultured rat hippocampal neurons

1998 • 142 citations

The Enhancement of Morphine Antinociception in Mice by Δ9-Tetrahydrocannabinol

1998 • 139 citations

Cannabinoid receptor-mediated inhibition of the rat tail-flick reflex after microinjection into the rostral ventromedial medulla

1998 • 138 citations

Molecular Aspects of Cannabinoid Receptors

1997 • 137 citations

Acute and residual effects of marijuana: Profiles of plasma THC levels, physiological, subjective, and performance measures

1990 • 135 citations

Marihuana and driving

1985 • 132 citations

Activation of the cannabinoid receptor by Δ9-tetrahydrocannabinol reduces γ-aminobutyric acid uptake in the globus pallidus

1996 • 131 citations

Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs.

1993 • 131 citations

The Safety and Pharmacokinetics of Single-Agent and Combination Therapy with Megestrol Acetate and Dronabinol for the Treatment of HIV Wasting Syndrome

1997 • 128 citations

A comparison of D1 receptor binding and mRNA in rat brain using receptor autoradiographic and in situ hybridization techniques

1992 • 128 citations

Dopaminergic Regulation of Cannabinoid Receptor mRNA Levels in the Rat Caudate‐Plitamen: An In Situ Hybridization Study

1993 • 125 citations

Interactions between delta 9-tetrahydrocannabinol and kappa opioids in mice.

1994 • 125 citations

Aminoalkylindoles: actions on specific G-protein-linked receptors.

1991 • 124 citations

CB1 receptor antagonist precipitates withdrawal in mice exposed to Delta9-tetrahydrocannabinol.

1998 • 123 citations

The Cannabinoids as Potential Antiepileptics

1981 • 123 citations

Modulation of cannabinoid-induced antinociception after intracerebroventricular versus intrathecal administration to mice: possible mechanisms for interaction with morphine.

1995 • 120 citations

Carry-over effects of marijuana intoxication on aircraft pilot performance: a preliminary report

1985 • 118 citations

Characterization of two cloned human CB1 cannabinoid receptor isoforms.

1996 • 118 citations

The role of endogenous opioids in enhancing the antinociception produced by the combination of delta 9-tetrahydrocannabinol and morphine in the spinal cord.

1996 • 116 citations

The ATP- and CoA-independent synthesis of arachidonoylethanolamide. A novel mechanism underlying the synthesis of the endogenous ligand of the cannabinoid receptor.

1994 • 116 citations

STRUCTURAL REQUIREMENTS FOR CANNABINOID ACTIVITY*

1971 • 113 citations

Cannabinoid-induced antinociception is mediated by a spinalα2-noradrenergic mechanism

1991 • 113 citations

Neurotoxicology of cannabis and THC: A review of chronic exposure studies in animals

1991 • 111 citations

Delta9-tetrahydrocannabinol induces apoptosis in macrophages and lymphocytes: involvement of Bcl-2 and caspase-1.

1998 • 108 citations

Analgesic properties of the tetrahydrocannabinols, their metabolites, and analogs

1975 • 100 citations

HU-211, a Novel Noncompetitive N -Methyl- <scp>d-</scp> Aspartate Antagonist, Improves Neurological Deficit and Reduces Infarct Volume After Reversible Focal Cerebral Ischemia in the Rat

1995 • 97 citations

Identification of cannabinoid receptors in cultures of rat cerebellar granule cells

1993 • 96 citations

Effects of the cannabinoids on physical properties of brain membranes and phospholipid vesicles: fluorescence studies.

1985 • 96 citations

Genetic and physical mapping of the human cannabinoid receptor gene to chromosome 6q14-q15.

1991 • 96 citations

Analgesic, respiratory and heart rate effects of cannabinoid and opioid agonists in rhesus monkeys: antagonist effects of SR 141716A.

1998 • 95 citations

The evidence for the existence of cannabinoid receptors

1993 • 94 citations

Effects of intrastriatal cannabinoids on rotational behavior in rats: Interactions with the dopaminergic system

1998 • 94 citations

Opioid and Cannabinoid Receptor Inhibition of Adenylyl Cyclase in Braina

1992 • 94 citations

THE ACTIVATION OF CANNABINOID RECEPTORS IN STRIATONIGRAL GABAERGIC NEURONS INHIBITED GABA UPTAKE

1997 • 93 citations

Chronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain

1998 • 91 citations

Relative efficacies of cannabinoid CB1 receptor agonists in the mouse brain

1997 • 91 citations

Enhancement by chlordiazepoxide of catalepsy induced in rats by intravenous or intrapallidal injections of enantiomeric cannabinoids

1991 • 88 citations

Cannabinoid-precipitated withdrawal: a time-course study of the behavioral aspect and its correlation with cannabinoid receptors and G protein expression.

1998 • 85 citations

Tetrahydrocannabinol-Induced Suppression of Macrophage Spreading and Phagocytic Activity In Vitro

1986 • 83 citations

Marijuana effect and delta-9-tetrahydrocannabinol plasma level

1984 • 83 citations

Loss of cannabinoid receptor binding and messenger RNA levels and cannabinoid agonist-stimulated [35s]guanylyl-5′-O-(thio)-triphosphate binding in the basal ganglia of aged rats

1998 • 82 citations

Role of the Subthalamic Nucleus in Cannabinoid Actions in the Substantia Nigra of the Rat

1997 • 80 citations

Drugs which stimulate or facilitate central cholinergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice

1991 • 80 citations

Blockade of cannabinoid-induced antinociception by norbinaltorphimine, but not N,N-diallyl-tyrosine-Aib-phenylalanine-leucine, ICI 174,864 or naloxone in mice.

1993 • 80 citations

Examination of the effect of the cannabinoid receptor agonist, CP 55,940, on electrically evoked transmitter release from rat brain slices

1997 • 79 citations

Acute effects of marijuana on cognition: Relationships to chronic effects and smoking techniques

1992 • 77 citations

Cannabinoid effects in basal ganglia in a rat model of Parkinson's disease

1998 • 76 citations

Cannabinoid receptors and their endogenous agonist, anandamide.

1998 • 76 citations

influence of marijuana on driving

1994 • 76 citations

Effects of intranigral cannabinoids on rotational behavior in rats: interactions with the dopaminergic system

1996 • 75 citations

Electroencephalographic correlates of marihuana-induced euphoria

1995 • 75 citations

Role of cyclic amp dependent protein kinase in cannabinoid receptor modulation of potassium “A-current” in cultured rat hippocampal neurons

1995 • 70 citations

Intrastriatal injection of cannabinoid receptor agonists induced turning behavior in mice

1995 • 67 citations

Tetrahydrocannabinol potentiates reserpine-induced hypokinesia

1981 • 65 citations

Inhibition of the Cyclic AMP Signaling Cascade and Nuclear Factor Binding to CRE and κB Elements by Cannabinol, a Minimally CNS-Active Cannabinoid

1998 • 65 citations

Cannabinoid Receptor‐Regulated Cyclic AMP Accumulation in the Rat Striatum

1991 • 64 citations

Chronic treatment with a synthetic cannabinoid CP-55,940 alters G-protein expression in the rat central nervous system

1997 • 62 citations

Behavioral comparisons of the stereoisomers of tetrahydrocannabinols

1981 • 62 citations

Rat brain cannabinoid receptors are N-linked glycosylated proteins

1995 • 62 citations

Catalepsy induced by intrastriatal injections of Δ9-THC and 11-OH-Δ9-THC in the rat

1978 • 61 citations

Extrapyramidal effects of methanandamide, an analog of anandamide, the endogenous CB1, receptor ligand

1996 • 59 citations

Cannabinoid receptor genes

1996 • 59 citations

Expression of the CB1 cannabinoid receptor in macrophage-like cells from brain tissue: immunochemical characterization by fusion protein antibodies

1998 • 58 citations

Persistent Topographic Quantitative EEG Sequelae of Chronic Marihuana Use: A Replication Study and Initial Discriminant Function Analysis

1994 • 57 citations

Characterization of anandamide-induced tolerance: comparison to Δ9-THC-induced interactions with dynorphinergic systems

1997 • 56 citations

Drugs which stimulate or facilitate central GABAergic transmission interact synergistically with delta-9-tetrahydrocannabinol to produce marked catalepsy in mice

1988 • 55 citations

Effects of anandamide and arachidonic acid on specific binding of (+)-PN200-110, diltiazem and (−)-desmethoxyverapamil to L-type Ca2+ channel

1996 • 55 citations

Glucocorticoid regulation of cannabinoid receptor messenger RNA levels in the rat caudate-putamen. An in situ hybridization study

1993 • 48 citations

An Assessment of the Role of Opioid Receptors in the Response to Cannabimimetic Drugs

1986 • 45 citations

The cannabinoid receptor: Biochemical and cellular properties in neuroblastoma cells

1991 • 44 citations

The pharmacologic effects of daily marijuana smoking in humans

1991 • 43 citations

Suppression of Human Macrophage Function In Vitro by δ9-Tetrahydrocannabinol

1991 • 39 citations

Tolerance to and dependence on psychotropic cannabinoids

1992 • 39 citations

Delta-9-tetrahydrocannabinol-induced catalepsy in mice is enhanced by pretreatment with flurazepam or chlordiazepoxide

1988 • 37 citations

Induction of Interleukin-2 Receptor α Gene by Δ⁹-Tetrahydrocannabinol Is Mediated by Nuclear Factor κB and CB1 Cannabinoid Receptor

1997 • 36 citations

Cardiovascular Effects of Marihuana in Man

1974 • 35 citations

Evaluation of the Accuracy of On-Site Multi-Analyte Drug Testing Devices in the Determination of the Prevalence of Illicit Drugs in Drivers

1998 • 34 citations

Relative pharmacological potency in mice of optical isomers of Δ1-tetrahydrocannabinol

1974 • 34 citations

The cannabinoid receptor: Computer-aided molecular modeling and docking of ligand

1997 • 33 citations

Hashish. Importance of the phenolic hydroxyl group in tetrahydrocannabinols

1975 • 31 citations

Delta 9-tetrahydrocannabinol inhibits arachidonic acid acylation of phospholipids and triacylglycerols in guinea pig cerebral cortex slices.

1991 • 31 citations

Chronic cannabinoid, CP-55,940, administration alters biotransformation in the rat

1996 • 30 citations

Glutamatergic regulation of cannabinoid receptor gene expression in the caudate-putamen

1994 • 27 citations

HindIII identifies a two allele DNA polymorphism of the human cannabinoid receptor gene (CNR)

1991 • 26 citations

Cannabis and brain function

1998 • 21 citations

Chronic marijuana smoke alters alveolar macrophage morphology and protein expression

1991 • 21 citations

Biosynthesis of 2-Arachidonoyl-Glycerol, a Novel Cannabimimetic Eicosanoid, in Mouse Neuroblastoma Cells

1997 • 19 citations

Hashish: synthesis and central nervous system activity of some novel analogs of cannabidiol and oxepin derivatives of .DELTA.9-tetrahydrocannabinol

1985 • 18 citations

The Discovery of Nonclassical Cannabinoid Analgetics

2019 • 15 citations

The pyrolysis of cannabinoids

1987 • 14 citations