Unpaired cysteine-54 interferes with the ability of an engineered disulfide to stabilize T4 lysozyme

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

[2] New M13 vectors for cloning

1983 • 5,402 citations

The Anatomy and Taxonomy of Protein Structure

1981 • 3,376 citations

[32] Oligonucleotide-directed mutagenesis of DNA fragments cloned into M13 vectors

1983 • 1,093 citations

Disulphide bridges in globular proteins

1981 • 770 citations

たんぱく質‐色素結合の原理を用いるμg量のたんぱく質の定量のための迅速,高感度法

1976 • 752 citations

The gapped duplex DNA approach to oligonucleotide-directed mutation construction

1984 • 511 citations

The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit β-globin DNA

1981 • 473 citations

Formation of three-dimensional structure in proteins. I. Rapid nonenzymic reactivation of reduced lysozyme

1970 • 394 citations

Site-Specific Mutagenesis of the Human Interleukin-2 Gene: Structure-Function Analysis of the Cysteine Residues

1984 • 328 citations

Disulfide Bond Engineered into T4 Lysozyme: Stabilization of the Protein Toward Thermal Inactivation

1984 • 311 citations

Real-Time Color Graphics in Studies of Molecular Interactions

1981 • 229 citations

Side-chain Interactions Governing the Pairing of Half-cystine Residues in Ribonuclease

1962 • 227 citations

Purification of Bacteriophage T4 Lysozyme

1968 • 225 citations

Directed Mutagenesis of Dihydrofolate Reductase

1983 • 210 citations

Site-specific mutagenesis of the human fibroblast interferon gene.

1984 • 193 citations

Mutants of Escherichia coli permeable to actinomycin.

1967 • 170 citations

Thermodynamic stability and point mutations of bacteriophage T4 lysozyme

1984 • 149 citations

Structure of the lysozyme from bacteriophage T4: An electron density map at 2.4 Å resolution

1978 • 132 citations

Location of sulfhydryl and disulfide groups in bovine .beta.-lactoglobulins and effects of urea

1972 • 109 citations

Reversible sulfhydryl-catalyzed structural alteration of bovine mercaptalbumin

1971 • 98 citations

Microheterogeneity of plasma albumins. V. Permutations in disulfide pairings as a probable source of microheterogeneity in bovine albumin

1969 • 82 citations

Roles of the 29-138 disulfide bond of subtype A of human .alpha. interferon in its antiviral activity and conformational stability

1984 • 66 citations

Evidence for intermediates during unfolding and refolding of a two-domain protein: phage T4 lysozyme equilibrium and kinetic studies

1984 • 37 citations

Non-toxic expression in Escherichia coli of a plasmid-encoded gene for phage T4 lysozyme

1985 • 32 citations