TNF-α inhibits asbestos-induced cytotoxicity via a NF-κB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis
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References (49)
Cancer: Principles and Practice of Oncology.
1991 • 8,402 citations
Death Receptors: Signaling and Modulation
1998 • 5,873 citations
NF-κB: linking inflammation and immunity to cancer development and progression
2005 • 2,878 citations
Induction of TNF Receptor I-Mediated Apoptosis via Two Sequential Signaling Complexes
2003 • 2,545 citations
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 • 2,370 citations
IKKβ Links Inflammation and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer
2004 • 2,361 citations
A lentivirus-based system to functionally silence genes in primary mammalian cells, stem cells and transgenic mice by RNA interference
2003 • 1,515 citations
Cancer—Principles & Practice of Oncology
1983 • 1,403 citations
Novel Inhibitors of Cytokine-induced IκBα Phosphorylation and Endothelial Cell Adhesion Molecule Expression Show Anti-inflammatory Effects in Vivo
1997 • 1,045 citations
Mechanisms in the Pathogenesis of Asbestosis and Silicosis
1998 • 913 citations
Asbestos: Scientific Developments and Implications for Public Policy
1990 • 763 citations
Inflammation as a tumor promoter in cancer induction
2004 • 608 citations
Inhibition of NF-κB in cancer cells converts inflammation- induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression
2004 • 598 citations
NF-κB as a therapeutic target in cancer
2002 • 550 citations
Interaction of NF-κB and NFAT with the Interferon-γ Promoter
1997 • 427 citations
The pathogenesis of mesothelioma
2002 • 389 citations
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosis.
1995 • 364 citations
Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposure.
1993 • 329 citations
Essential role of tumor necrosis factor alpha (TNF-alpha) in tumor promotion as revealed by TNF-alpha-deficient mice.
1999 • 308 citations
Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity
2000 • 241 citations
Cytokines and particle-induced inflammatory cell recruitment.
1997 • 199 citations
A Phase II Study of Etanercept (Enbrel), a Tumor Necrosis Factor α Inhibitor in Patients with Metastatic Breast Cancer
2004 • 193 citations
Genetic Predisposition to Fiber Carcinogenesis Causes a Mesothelioma Epidemic in Turkey
2006 • 169 citations
Tumour necrosis factor-α mediates tumour promotion via a PKCα- and AP-1-dependent pathway
2002 • 164 citations
TNF-α Receptor Knockout Mice Are Protected from the Fibroproliferative Effects of Inhaled Asbestos Fibers
1998 • 146 citations
Cellular and molecular mechanisms of asbestos‐induced fibrosis
1999 • 111 citations
Chronic inflammation, apoptosis and (pre-)malignant lesions in the gastro-intestinal tract
2004 • 108 citations
Ribonucleases as a Novel Pro-Apoptotic Anticancer Strategy: Review of the Preclinical and Clinical Data for Ranpirnase
2005 • 101 citations
Asbestos causes translocation of p65 protein and increases NF-kappa B DNA binding activity in rat lung epithelial and pleural mesothelial cells.
1997 • 98 citations
Asbestos-Induced Pulmonary Toxicity: Role of DNA Damage and Apoptosis
2003 • 98 citations
TNF-α regulates epithelial expression of MMP-9 and integrin αvβ6 during tumour promotion. A role for TNF-α in keratinocyte migration?
2004 • 89 citations
Mechanisms of the genotoxicity of crocidolite asbestos in mammalian cells: implication from mutation patterns induced by reactive oxygen species.
2002 • 86 citations
Human Alveolar Macrophage Cytokine Release in Response to in Vitro and in Vivo Asbestos Exposure
1993 • 83 citations
Nuclear factor kappaB inhibitors induce adhesion-dependent colon cancer apoptosis: implications for metastasis.
2002 • 80 citations
Pleural macrophage recruitment and activation in asbestos-induced pleural injury.
1997 • 80 citations
Role of phagocytosis in Syrian hamster cell transformation and cytogenetic effects induced by asbestos and short and long glass fibers.
1986 • 77 citations
Discrete roles of cytokines, TNF-α, IL-1, IL-6 in tumor promotion and cell transformation
2002 • 67 citations
DISTINCTIVE PROFILE OF ALVEOLAR MACROPHAGEDERIVED CYTOKINE RELEASE INDUCED BY FIBROGENIC AND NONFIBROGENIC MINERAL DUSTS
1996 • 58 citations
Differential Regulation of Extracellular Signal-Regulated Kinase and Nuclear Factor-κB Signal Transduction Pathways by Hydrogen Peroxide and Tumor Necrosis Factor
1998 • 56 citations
An IkappaBalpha inhibitor causes leukemia cell death through a p38 MAP kinase-dependent, NF-kappaB-independent mechanism.
2001 • 49 citations
ASBESTOS EXPOSURE INDUCES MCP-1 SECRETION BY PLEURAL MESOTHELIAL CELLS
2000 • 36 citations
CYTOKINE AND FREE RADICAL RESPONSES OF ALVEOLAR MACROPHAGES IN VITRO TO ASBESTOS FIBRES
2000 • 29 citations
Asbestos fibre length-dependent detachment injury to alveolar epithelial cells in vitro: role of a fibronectin-binding receptor.
1993 • 28 citations
Tumor Necrosis Factor-α-induced Proliferation of Human Mo7e Leukemic Cells Occurs via Activation of Nuclear Factor κB Transcription Factor
1999 • 27 citations
Treatment of Jurkat acute T-lymphocytic leukemia cells by onconase (Ranpirnase) is accompanied by an altered nucleocytoplasmic distribution and reduced expression of transcription factor NF-κB
2004 • 25 citations
Asbestos induction of extended lifespan in normal human mesothelial cells: interindividual susceptibility and SV40 T antigen
1999 • 25 citations
Physical and chemical characteristics of UICC reference samples.
1980 • 19 citations
TNF-α increases tracheal epithelial asbestos and fiberglass binding via a NF-κB-dependent mechanism
2000 • 14 citations
The effects of erythromycin on the viability and the secretion of TNF‐α and TGF‐β1 and expression of connexin43 by human pleural mesothelial cells
2005 • 4 citations