Spatial and temporal patterning distinguishes the locomotor activating effects of dizocilpine and phencyclidine in rats

The current status of the dopamine hypothesis of schizophrenia

1988 • 962 citations

Study of a New Schizophrenomimetic Drug—Sernyl

1959 • 922 citations

The NMDA antagonist MK-801 causes marked locomotor stimulation in monoamine-depleted mice

1989 • 426 citations

Effects of phencyclidine and phencyclidine biologs on sensorimotor gating in the rat*1

1989 • 375 citations

MK-801, a proposed noncompetitive antagonist of excitatory amino acid neurotransmission, produces phencyclidine-like behavioral effects in pigeons, rats and rhesus monkeys.

1988 • 302 citations

Behavioral rating scales for assessing phencyclidine-induced locomotor activity, stereotypes behavior and ataxia in rats

1979 • 236 citations

Multivariate assessment of locomotor behavior: Pharmacological and behavioral analyses

1986 • 214 citations

The novel anticonvulsant MK-801: a potent and specific ligand of the brain phencyclidine/gd-receptor

1987 • 197 citations

Behavioral effects of MK-801 mimic deficits associated with hippocampal damage

1989 • 190 citations

Phencyclidine and psychotomimetic sigma opiates: recent insights into their biochemical and physiological sites of action

1988 • 189 citations

Evidence for a role of haloperidol‐sensitive σ‐'opiate' receptors in the motor effects of antipsychotic drugs

1988 • 183 citations

Dramatic synergism between MK-801 and clonidine with respect to locomotor stimulatory effect in monoamine-depleted mice

1989 • 174 citations

The Neuroprotective Action of Ketamine and MK-801 after Transient Cerebral Ischemia in Rats

1988 • 143 citations

Acute and chronic phencyclidine effects on locomotor activity, stereotypy and ataxia in rats

1981 • 141 citations

Interfering with glutamatergic neurotransmission by means of NMDA antagonist administration discloses the locomotor stimulatory potential of other transmitter systems

1990 • 123 citations

Involvement of extrapyramidal motor mechanisms in the suppression of locomotor activity by antipsychotic drugs: A comparison between the effects produced by pre- and post-synaptic inhibition of dopaminergic neurotransmission

1986 • 102 citations

Behavior during hippocampal microinfusions. I. Norepinephrine and diversive exploration

1982 • 96 citations

Phencyclidine-like discriminative stimulus properties of MK-801 in rats

1988 • 82 citations

The effect of MK-801 and other antagonists of NMDA-type glutamate receptors on brain-stimulation reward

1989 • 72 citations

A role for receptors of N-methyl-D-aspartic acid in the discriminative stimulus properties of phencyclidine

1987 • 71 citations

Effects of dopaminergic drugs on phencyclidine-induced behavior in the rat

1981 • 59 citations

Possible abuse potential of the NMDA antagonist MK-801

1989 • 59 citations

The topography of MK-801-induced locomotor patterns in rats

1989 • 53 citations

Phencyclidine: behavioral and biochemical evidence supporting a role for dopamine.

1983 • 50 citations

Increased startle responding in rats treated with phencyclidine.

1984 • 39 citations

Psychotogenic drugs as models for schizophrenia *1Comments on ?the current status of the dopamine hypothesis of schizophrenia?

1988 • 37 citations

Evidence for multiple opiate receptor involvement in different phencyclidine-induced unconditioned behaviors in rats

1986 • 30 citations

Pharmacological specificity of some psychotomimetic and antipsychotic agents for the sigma and PCP binding sites

1988 • 30 citations

Evaluation of antagonists of the discriminative stimulus and response rate effects of phencyclidine.

1988 • 24 citations

Functional evidence for PCP-like effects of the anti-stroke candidate MK-801

1988 • 22 citations

Effects of phencyclidine, haloperidol, and naloxone on fixed-interval performance in rats

1984 • 19 citations

In vivo characterization of phencyclidine/σ agonist-mediated inhibition of nociception

1989 • 16 citations