Mediation of the Immunomodulatory Effect of β-Estradiol on Inflammatory Responses by Inhibition of Recruitment and Activation of Inflammatory Cells and Their Gene Expression of TNF-α and IFN-γ

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

CELLULAR RESPONSES TO INTERFERON-γ

1997 • 2,885 citations

Endothelial Expression of a Mononuclear Leukocyte Adhesion Molecule During Atherogenesis

1991 • 1,703 citations

Atherosclerosis: Basic Mechanisms

1995 • 1,697 citations

Requirement for CD44 in Activated T Cell Extravasation into an Inflammatory Site

1997 • 560 citations

Regulatory CD4 T cells: expression of IL-2R alpha chain, resistance to clonal deletion and IL-2 dependency

1998 • 447 citations

Estrogen regulates the IFN-gamma promoter.

1991 • 409 citations

Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release.

1989 • 381 citations

Effect of estradiol on cytokine secretion by proteolipid protein-specific T cell clones isolated from multiple sclerosis patients and normal control subjects.

1997 • 311 citations

Sex steroid receptors in peripheral T cells: absence of androgen receptors and restriction of estrogen receptors to OKT8-positive cells.

1983 • 308 citations

Estradiol Down‐Regulates LPS‐Induced Cytokine Production and NFkB Activation in Murine Macrophages

1997 • 285 citations

Properties of monocyte chemotactic and activating factor (MCAF) purified from a human fibrosarcoma cell line.

1990 • 241 citations

The role of CD40/CD154 interactions in the priming, differentiation, and effector function of helper and cytotoxic T cells

1998 • 230 citations

Estrogen inhibits release of tumor necrosis factor from peripheral blood mononuclear cells in postmenopausal women

1990 • 229 citations

A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis

1997 • 188 citations

Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease.

1994 • 187 citations

Oestrogen Receptors in Macrophages

1990 • 183 citations

Estrogen modulation of JE/monocyte chemoattractant protein-1 mRNA expression in murine macrophages.

1995 • 180 citations

Regulation of the immune response by macrophage migration inhibitory factor: biological and structural features

1998 • 174 citations

Killing of Listeria monocytogenes by Inflammatory Neutrophils and Mononuclear Phagocytes From Immune and Nonimmune Mice

1984 • 162 citations

Estrogen accelerates immune complex glomerulonephritis but ameliorates T cell-mediated vasculitis and sialadenitis in autoimmune MRL lpr/lpr mice

1992 • 158 citations

Role of T lymphocytes in collagen II induced arthritis in rats.

1983 • 150 citations

Sex hormones and the immune system—part 2. Animal data

1990 • 146 citations

Secretion by human fibroblasts of monocyte chemoattractant protein-1, the product of gene JE.

1990 • 145 citations

Estradiol binding to cell surface raises cytosolic free calcium in T cells

1998 • 140 citations

Anti-inflammatory properties of estrogen

1992 • 140 citations

Vascular Smooth Muscle Cells as Target for Estrogen

1993 • 131 citations

Peripheral blood T cells and monocytes and B cell lines derived from patients with lupus express estrogen receptor transcripts similar to those of normal cells.

1998 • 124 citations

Presence of oestrogen receptors in human blood mononuclear cells and thymocytes

1986 • 116 citations

Female hormones reduce neutrophil responsiveness in vitro

1984 • 113 citations

Effects of Hormone Therapy on Inflammatory Cell Adhesion Molecules in Postmenopausal Healthy Women

1997 • 96 citations

The effects of gender and sex hormones on outcome in rheumatoid arthritis

1992 • 91 citations

Oestrogen induced suppression of collagen arthritis: I. Long term oestradiol treatment of DBA/1 mice reduces severity and incidence of arthritis and decreases the anti type II collagen immune response.

1987 • 90 citations

Physiological concentration of estradiol inhibits polymorphonuclear leukocyte chemotaxis via a receptor mediated system

1995 • 88 citations

Inhibition of leukocyte adhesion: an alternative mechanism of action for anti-inflammatory drugs

1998 • 79 citations

Effect of castration and sex hormones on experimental autoimmune thyroiditis

1981 • 75 citations

Does differential neuroendocrine control of cytokine production govern the expression of autoimmune diseases in pregnancy and the postpartum period?

1997 • 70 citations

Estrogens and Rheumatoid Arthritis

1992 • 58 citations

Modulation of Rat Peritoneal Mast Cell and Human Basophil Histamine Release by Estrogens

1990 • 54 citations

Estrogen suppression of connective tissue deposition in a murine model of peritoneal adhesion formation.

1996 • 52 citations

The Influence of Beta-Estradiol and Progesterone on Interferon Gamma Production in Vitro

1990 • 46 citations

Hormonal modulation of responses to thymus-independent and thymus-dependent antigens in autoimmune NZB/W mice.

1985 • 45 citations

Role of interleukin 1 and interleukin 2 in rat and mouse arthritis models.

1986 • 44 citations

Beta-estradiol-induced decrease in IL-12 and TNF-α expression suppresses macrophage functions in the course of Listeria monocytogenes infection in mice

1999 • 43 citations

Estrogen regulation of JE/MCP-1 mRNA expression in fibroblasts

1996 • 34 citations

Additive effects of suboptimal doses of estrogen and cortisone on the suppression of T lymphocyte dependent inflammatory responses in mice

1996 • 33 citations

Oestradiol suppression of delayed-type hypersensitivity in autoimmune (NZB/NZW)F1 mice is a trait inherited from the healthy NZW parental strain.

1989 • 31 citations

The influence of ovarian hormones on the granulomatous inflammatory process in the rat lung

1995 • 30 citations

Sex Hormones as Immunomodulators of Disease

1993 • 28 citations

Analysis of the genetic encoding of oestradiol suppression of delayed-type hypersensitivity in (NZB x NZW) F1 mice.

1991 • 27 citations

ESTRADIOL INHIBITS ALLOGRAFT-INDUCIBLE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS II ANTIGEN EXPRESSION AND TRANSPLANT ARTERIOSCLEROSIS IN THE ABSENCE OF IMMUNOSUPPRESSION1

1998 • 22 citations

Effect of Estradiol and Progesterone on the Low‐Dose Endotoxin‐Induced Glomerular Inflammatory Response of the Female Rat

1999 • 21 citations

Suppression of Delayed-Type Hypersensitivity in Mice Pretreated With Diethylstilbesterol: Involvement of Sex Hormones in Immunomodulation

1988 • 20 citations

Control of the expression of interleukin-2 activity

1982 • 16 citations

Suppression of Reproductive Function in Autoimmune NZB/W Mice: Effective Doses of Four Contraceptive Steroids

1987 • 8 citations

Effect of oestradiol on the secretory immune system in the rat: an increase in biliary IgM antibodies against a T-cell independent antigen.

1991 • 8 citations