The effects of recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) on human osteoblast-like cells

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Human granulocyte-macrophage colony-stimulating factor is a neutrophil activator

1985 • 566 citations

Osteoblasts synthesize and respond to transforming growth factor-type beta (TGF-beta) in vitro.

1987 • 561 citations

Tumor necrosis factors alpha and beta induce osteoblastic cells to stimulate osteoclastic bone resorption.

1987 • 539 citations

Purified Human Granulocyte-Macrophage Colony-Stimulating Factor: Direct Action on Neutrophils

1984 • 506 citations

Production of osteocalcin by human bone cells in vitro. Effects of 1,25(OH)2D3, 24,25(OH)2D3, parathyroid hormone, and glucocorticoids

1984 • 500 citations

Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts.

1986 • 392 citations

Human Recombinant Granulocyte-Macrophage Colony-Stimulating Factor: A Multilineage Hematopoietin

1985 • 374 citations

1,25-Dihydroxyvitamin D₃and Human Bone-Derived Cells in Vitro: Effects on Alkaline Phosphatase, Type I Collagen and Proliferation*

1986 • 280 citations

Stimulation of macrophage plasminogen activator activity by colony‐stimulating factors

1980 • 223 citations

Effects of human recombinant CSF-GM and highly purified CSF-1 on the formation of multinucleated cells with osteoclast characteristics in long-term bone marrow cultures

1986 • 215 citations

Type-β transforming growth factor inhibits proliferation and expression of alkaline phosphatase in murine osteoblast-like cells

1986 • 167 citations

Parathyroid Hormone Stimulates the Proliferation of Cells Derived from Human Bone*

1986 • 161 citations

Secretion of plasminogen activator by bone marrow-derived mononuclear phagocytes and its enhancement by colony-stimulating factor

1978 • 161 citations

Purification of fetal hematopoietic progenitors and demonstration of recombinant multipotential colony-stimulating activity.

1985 • 156 citations

Regulation of Plasminogen Activator Production by Bone-Resorbing Hormones in Normal and Malignant Osteoblasts*

1985 • 151 citations

Demonstration of burst-promoting activity of recombinant human GM-CSF on circulating erythroid progenitors using an assay involving the delayed addition of erythropoietin

1985 • 112 citations

Actions of recombinant human γ‐interferon and tumor necrosis factor α on the proliferation and osteoblastic characteristics of human trabecular bone cells in vitro

1988 • 112 citations

Murine osteoblastlike cells and the osteogenic cell MC3T3-E1 release a macrophage colony-stimulating activity in culture

1987 • 99 citations

Stimulation of plasminogen activator in osteoblast-like cells by bone-resorbing hormones

1984 • 95 citations

Induction of proliferation of purified human myeloid progenitor cells: a rapid assay for granulocyte colony-stimulating factors

1984 • 93 citations

Local Production of Colony-stimulating Factor Within the Bone Marrow: Role of Nonhematopoietic Cells

1972 • 87 citations

Osteocalcin and bone morphometric parameters in adults without bone disease

1988 • 86 citations

Recombinant human interleukin 1 alpha and beta stimulate mouse osteoblast-like cells (MC3T3-E1) to produce macrophage-colony stimulating activity and prostaglandin E2

1986 • 84 citations

Tumor necrosis factor type α (cachectin) stimulates mouse osteoblast-like cells (MC3T3-E1) to produce macrophage-colony stimulating activity and prostaglandin E2

1987 • 78 citations

Production of hemopoietic growth factors by bone tissue and bone cells in culture

1988 • 67 citations

Association of hypercalcemia with tumors producing colony-stimulating factor(s).

1983 • 66 citations

Synthesis of colony-stimulating factor (CSF) and differentiation-inducing factor (D-factor) by osteoblastic cells, clone MC3T3-E1

1986 • 63 citations

Interleukin-1 induces human bone marrow-derived fibroblasts to produce multilineage hematopoietic growth factors.

1987 • 61 citations

Transforming growth factor-β reduces the phenotypic expression of osteoblastic MP3T3-E1 cells in monolayer culture

1987 • 60 citations

Granulocyte‐macrophage colony formation in serum‐free culture: Effects of purified colony‐stimulating factors and modulation by hydrocortisone

1986 • 53 citations

Modulation of connective tissue metabolism by partially purified human interleukin 1

1985 • 49 citations

Retinoids and synovial factor(s) stimulate the production of plasminogen activator by cultured human chondrocytes. A possible role for plasminogen activator in the resorption of cartilage in vitro

1985 • 31 citations

Monokines and Other Non-Lymphocytic Cytokines

1989 • 25 citations

Production of granulocyte-stimulating and bone cell-modulating activities from a neutrophilia hypercalcemia-inducing murine mammary cancer cell line.

1987 • 18 citations