Retinoids and synovial factor(s) stimulate the production of plasminogen activator by cultured human chondrocytes. A possible role for plasminogen activator in the resorption of cartilage in vitro

Microdetermination of Phosphorus

1956 • 7,242 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 779 citations

SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES

1974 • 719 citations

The effect of hypervitaminosis A on embryonic limb‐bones cultivated in vitro

1952 • 316 citations

Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro

1984 • 281 citations

Studies on the mode of action of excess of vitamin A. 2. A possible role of intracellular proteases in the degradation of cartilage matrix

1961 • 199 citations

Phorbol ester-induced morphological changes in transformed chick fibroblasts: Evidence for direct catalytic involvement of plasminogen activator

1979 • 168 citations

Association of a protease (plasminogen activator) with a specific membrane fraction isolated from transformed cells.

1976 • 163 citations

The preparation of human fibrinogen free of plasminogen

1962 • 149 citations

Human synovium releases a factor which stimulates chondrocyte production of PGE and plasminogen activator

1980 • 134 citations

Plasminogen activator in chick fibroblasts: Induction of synthesis by retinoic acid; synergism with viral transformation and phorbol ester

1978 • 132 citations

In vitro activation of human chondrocytes and synoviocytes by a human interleukin‐1‐like factor

1984 • 125 citations

Inflammation and Collagenase Production in Rats with Adjuvant Arthritis Reduced with 13- cis -Retinoic Acid

1983 • 121 citations

An inhibitor of plasminogen activator in rabbit endothelial cells.

1981 • 108 citations

Degradation of connective tissue matrices by macrophages. II. Influence of matrix composition on proteolysis of glycoproteins, elastin, and collagen by macrophages in culture.

1980 • 102 citations

Stimulation of human synovial fibroblast plasminogen activator production by mononuclear cell supernatants.

1981 • 101 citations

An improved assay for proteases and polysaccharidases employing a cartilage proteoglycan substrate entrapped in polyacrylamide particles

1980 • 83 citations

Purification to homogeneity of pig leucocyte catabolin, a protein that causes cartilage resorption in vitro

1983 • 81 citations

Regulation of extracellular plasminogen activator by human fibroblasts. The role of protease nexin.

1983 • 65 citations

Macrophage Factor that Induces Neutral Protease Secretion by Normal Rabbit Chondrocytes

1980 • 63 citations

Characterization of proteins from human synovium and mononuclear leucocytes that induce resorption of cartilage proteoglycan in vitro

1983 • 60 citations

The site of cartilage matrix degradation

1980 • 45 citations

Effects of retinoic acid on plasminogen activator and mitogenic responses of cultured mouse cells.

1980 • 44 citations

Differential release of plasminogen activator and latent collagenase from mononuclear cell‐stimulated synovial cells

1983 • 36 citations

Effects of retinol and dexamethasone on cytokine-mediated control of metalloproteinases and their inhibitors by human articular chondrocytes and synovial cells in culture

1983 • 36 citations

Evidence that extracellular cathepsin D is not responsible for the resorption of cartilage matrix in culture

1982 • 33 citations

Stimulation of the plasminogen activator activity of human synovial fibroblasts by retinoids

1982 • 31 citations

Chapter 22 Proteases and Cell Invasion

1979 • 25 citations

Plasminogen activation by normal B lymphocytes, a function associated with the cell membrane.

1981 • 21 citations

Expression of the catalytic activity of plasminogen activator under physiologic conditions

1981 • 20 citations

Characterization of a plasma membrane-associated plasminogen activator on thymocytes

1981 • 18 citations