Modulation of connective tissue metabolism by partially purified human interleukin 1

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

An interleukin 1 like factor stimulates bone resorption in vitro

1983 • 1,017 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 921 citations

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

Endogenous Activation of Latent Collagenase by Rheumatoid Synovial Cells

1977 • 686 citations

The functional relationship of the interleukins.

1980 • 660 citations

Isolation of an interleukin‐1‐like factor from human joint effusions

1983 • 450 citations

Interleukin 1 stimulation of collagenase production by cultured fibroblasts.

1983 • 373 citations

Purification of rabbit bone inhibitor of collagenase

1981 • 352 citations

Interleukin 1 activity in the synovial fluid of patients with rheumatoid arthritis

1982 • 304 citations

Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro

1984 • 281 citations

Collagenase Production by Rheumatoid Synovial Cells: Stimulation by a Human Lymphocyte Factor

1977 • 275 citations

Specificities of Prostaglandins B1, F1α, and F2α Antigen-Antibody Reactions

1971 • 260 citations

Endogenous pyrogens made by rabbit peritoneal exudate cells are identical with lymphocyte-activating factors made by rabbit alveolar macrophages.

1980 • 260 citations

A cartilage catabolic factor from synovium

1979 • 246 citations

The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen

1981 • 224 citations

Prostaglandin production by rheumatoid synovial cells: stimulation by a factor from human mononuclear Cells.

1977 • 188 citations

Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation.

1981 • 138 citations

Human synovium releases a factor which stimulates chondrocyte production of PGE and plasminogen activator

1980 • 134 citations

Synthesis of collagenase and neutral proteases by articular chondrocytes: Stimulation by a macrophage-derived factor

1978 • 132 citations

Partial Purification of Human Lymphocyte-Activating Factor (LAF) by Ultrafiltration and Electrophoretic Techniques

1977 • 124 citations

Interactions among rheumatoid synovial cells and monocyte-macrophages: production of collagenase-stimulating factor by human monocytes exposed to concanavalin A or immunoglobulin Fc fragments.

1980 • 122 citations

A tissue-culture model of cartilage breakdown in rheumatoid arthritis. Quantitative aspects of proteoglycan release

1979 • 108 citations

Studies on the purification and structure-function relationships of murine lymphocyte activating factor (interleukin 1)

1980 • 103 citations

Action of Plasmin on Cartilage

1958 • 91 citations

Induction of the synthesis of latent collagenase and latent neutral protease in chondrocytes by a factor synthesized by activated macrophages

1980 • 90 citations

Characterization of Lymphocyte-Activating Factor (LAF) Produced by Human Mononuclear Cells: Biochemical Relationship of High and Low Molecular Weight Forms of LAF

1979 • 88 citations

Stimulation of bone resorption in vitro by a non-prostanoid factor released by human monocytes in culture

1983 • 86 citations

Mechanism of action of human B cell-activating factor. I. Comparison of the plaque-stimulating activity with thymocyte-stimulating activity.

1979 • 63 citations

Effects of products from macrophages, blood mononuclear cells and of retinol on collagenase secretion and collagen synthesis in chondrocyte culture

1982 • 54 citations

Mechanism of Action of Human B Cell-Activating Factor

1979 • 48 citations

Studies on the active site of human leukocytic pyrogen

1982 • 38 citations

Effects of retinol and dexamethasone on cytokine-mediated control of metalloproteinases and their inhibitors by human articular chondrocytes and synovial cells in culture

1983 • 36 citations

Enhanced production of prostaglandins and plasminogen activator during activation of human articular chondrocytes by products of mononuclear cells

1984 • 15 citations

Intercellular Messengers in Joint Tissues in Rheumatoid Arthritis

1981 • 15 citations