A nitric oxide-releasing nonsteroidal anti-inflammatory drug accelerates gastric ulcer healing in rats

Selective inhibition of inducible cyclooxygenase 2 in vivo is antiinflammatory and nonulcerogenic.

1994 • 1,322 citations

Differential inhibition of prostaglandin endoperoxide synthase (cyclooxygenase) isozymes by aspirin and other non-steroidal anti-inflammatory drugs.

1993 • 1,270 citations

Non-steroidal anti-inflammatory drugs and life threatening complications of peptic ulceration.

1987 • 643 citations

PREVENTION OF NSAID-INDUCED GASTRIC ULCER WITH MISOPROSTOL: MULTICENTRE, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

1988 • 615 citations

HIV TESTING ON ALL PREGNANT WOMEN

1987 • 367 citations

Mitogen‐inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs

1992 • 313 citations

Novel nonsterodial anti-inflammatory drug derivatives with markedly reduced ulcerogenic properties in the rat

1994 • 293 citations

Role of epidermal growth factor in healing of chronic gastroduodenal ulcers in rats

1988 • 274 citations

The vasodilator role of endogenous nitric oxide in the rat gastric microcirculation

1989 • 254 citations

Nitric oxide generators and cGMP stimulate mucus secretion by rat gastric mucosal cells

1993 • 194 citations

Increased expression of epidermal growth factor receptor during gastric ulcer healing in rats

1992 • 188 citations

Inhibition of nitric oxide synthase delays healing of chronic gastric ulcers

1993 • 188 citations

Inhibitory effect of non-steroidal anti-inflammatory drugs on mucosal cell proliferation associated with gastric ulcer healing

1990 • 182 citations

The selective beneficial effects of nitric oxide inhibition in experimental colitis

1995 • 169 citations

A diclofenac derivative without ulcerogenic properties

1994 • 167 citations

Delayed Healing of Acetic Acid-Induced Gastric Ulcers in Rats by Indomethacin

1989 • 166 citations

Accelerated healing of duodenal ulcers by oral administration of a mutein of basic fibroblast growth factor in rats

1994 • 151 citations

Misoprostol Heals Gastroduodenal Injury in Patients With Rheumatoid Arthritis Receiving Aspirin

1989 • 134 citations

Influence of acid and angiogenesis on kinetics of gastric ulcer healing in rats: interaction with indomethacin

1995 • 107 citations

The development of gastrointestinal-sparing nonsteroidal anti-inflammatory drugs

1994 • 90 citations

Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: Anti-inflammatory without gastropathy?

1993 • 74 citations

Markedly reduced intestinal toxicity of a diclofenac derivative

1994 • 70 citations

Hepatic and gastric cytoprotective effects of long-term prostaglandin E1 administration in cirrhotic rats

1993 • 46 citations

Diclofenac delays healing of gastroduodenal mucosal lesions

1991 • 46 citations

Effects of misoprostol on delayed ulcer healing induced by aspirin

1994 • 30 citations

The TCA cycle as an oxidative and synthetic pathway is suppressed with aging in jejunal epithelial cells

1994 • 30 citations

Healing of chronic gastroduodenal ulcerations by antacids

1990 • 27 citations

Misoprostol heals gastroduodenal injury in patients with rheumatoid arthritis receiving aspirin

1989 • 19 citations

Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat

1994 • 17 citations

The effect of 15(R)-15-methyl prostaglandin E2 (Arbacet) on the healing of aspirin or nonsteroidal antiinflammatory drug-induced gastric mucosal lesions: an endoscopic study.

1987 • 3 citations