Tissue-selective inhibition of prostaglandin synthesis in rat by tepoxalin: Anti-inflammatory without gastropathy?

Inhibition of Prostaglandin Synthesis as a Mechanism of Action for Aspirin-like Drugs

1971 • 8,596 citations

Expression of a mitogen-responsive gene encoding prostaglandin synthase is regulated by mRNA splicing.

1991 • 1,734 citations

Cytoprotection by prostaglandins

1979 • 1,076 citations

Inhibition of Prostaglandin Synthetase in Brain explains the Anti-pyretic Activity of Paracetamol (4-Acetamidophenol)

1972 • 773 citations

PREVENTION OF NSAID-INDUCED GASTRIC ULCER WITH MISOPROSTOL: MULTICENTRE, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL

1988 • 615 citations

Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process

1990 • 563 citations

Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease

1989 • 433 citations

Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa

1980 • 401 citations

HIV TESTING ON ALL PREGNANT WOMEN

1987 • 367 citations

Mitogen‐inducible prostaglandin G/H synthase: A new target for nonsteroidal antiinflammatory drugs

1992 • 313 citations

A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit

1991 • 284 citations

Indomethacin-induced leukocyte adhesion in mesenteric venules: role of lipoxygenase products

1992 • 206 citations

Modulation of leukocyte adhesion in rat mesenteric venules by aspirin and salicylate

1992 • 163 citations

The effects of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal antiinflammatory drugs in mice

1987 • 159 citations

Pathogenesis of NSAID gastropathy: are neutrophils the culprits?

1992 • 134 citations

Vascular injury in acute gastric mucosal damage

1988 • 91 citations

Pharmacological investigation of the role of leukotrienes in the pathogenesis of experimental NSAID gastropathy

1992 • 79 citations

Role of prostanoids in the protective actions of BW755C on the gastric mucosa

1985 • 77 citations

The Relationship Between Nonsteroidal Anti-inflammatory Drug Use and Peptic Ulcer Disease

1990 • 64 citations

Role of leukotriene C4 in mucosal damage caused by necrotizing agents and indomethacin in the rat stomach

1991 • 62 citations

Mechanisms underlying the protective effects of interleukin 1 in experimental nonsteroidal anti-inflammatory drug gastropathy

1992 • 47 citations

Characterization of a simple animal model for nonsteroidal anti-inflammatory drug induced antral ulcer

1993 • 28 citations

Nonessential role of leukotrienes as mediators of acute gastric mucosal injury induced by aspirin in rats

1992 • 25 citations

Effects of sodium salicylate and acetylsalicylic acid on intramural pH and ulceration of rabbit antral mucosa.

1982 • 21 citations

Comparison of the ulcerogenic properties of tepoxalin with those of non-steroidal anti-inflammatory drugs (NSAIDs)

1991 • 20 citations

Mechanisms underlying the protective effects of interleukin 1 in experimental nonsteroidal anti-inflammatory drug gastropathy

1992 • 17 citations

Mechanisms underlying the protective effects of interleukin-1 in experimental NSAID-gastropathy.

1992 • 11 citations

The pathogenesis of NSAID-gastropathy-are neutrophils the culprits?

1992 • 10 citations