Gastrointestinal irritancy, antiinflammatory activity, and prostanoid inhibition in the rat

Aspirin Selectively Inhibits Prostaglandin Production in Human Platelets

1971 • 1,535 citations

Cytoprotection by prostaglandins

1979 • 1,076 citations

Inhibition of the inflammatory action of interleukin-1 and tumor necrosis factor (alpha) on neutrophil function by pentoxifylline

1988 • 384 citations

Increased superoxide anion release from human endothelial cells in response to cytokines.

1986 • 365 citations

PATHWAY TO CARRAGEENANINDUCED INFLAMMATION OF THE HIND LIMB OF THE RAT

1987 • 281 citations

The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammation

1980 • 244 citations

Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

1978 • 206 citations

Nabumetone (BRL 14777, 4-[6-methoxy-2-naphthyl]-butan-2-one): a new anti-inflammatory agent

1982 • 65 citations

Histamine‐stimulated hydrogen ion secretion by in vitro piglet gastric mucosa.

1975 • 64 citations

The role of copper in preventing gastrointestinal damage by acidic anti-inflammatory drugs

1976 • 63 citations

The Metabolic Disposition of Etodolac in Rats, Dogs, and Man

1981 • 60 citations

Effect of Naproxen and of Aspirin on Bleeding Time and Platelet Aggregation

1974 • 47 citations

Correlation between gastric irritancy and anti-inflammatory activity of non-steroidal anti-inflammatory drugs

1984 • 41 citations

Comparison in rats of the anti-inflammatory and gastric irritant effects of etodolac1 with several clinically effective anti-inflammatory drugs

1982 • 39 citations

Endoscopic studies of nabumetone in patients with rheumatoid arthritis

1987 • 31 citations

Effect of nabumetone (BRL 14777), a new anti-inflammatory drug, on human platelet reactivity ex vivo: comparison with naproxen

1982 • 31 citations

An overview of the efficacy of etodolac in arthritic disorders.

1990 • 27 citations

The enterohepatic circulation of some anti-inflammatory drugs may cause intestinal ulcerations

1987 • 19 citations

Comparative Gastrointestinal Blood Loss Associated with Placebo, Aspirin, and Nabumetone as Assessed by Radiochromium (⁵¹Cr)

1989 • 19 citations

Nonsteroidal Anti‐inflammatory Drugs

1987 • 16 citations

Comparison of the effects of nabumetone with indomethacin on rat gastric mucosal 6-keto-PGF1α production and on bile salt-induced changes in gastric mucosal function

1987 • 16 citations

New Understandings of NSAID Gastropathy

1989 • 15 citations

Etodolac: Effect on prostaglandin concentrations in gastric mucosa of rats

1985 • 14 citations

Observations on the delay in onset of the acute phase protein response.

1988 • 14 citations

Interaction between Nabumetone – a New Non-Steroidal Anti-Inflammatory Drug – and the Haemostatic System ex vivo

1990 • 13 citations

A rat gastric mucosal preparation for studying agents which affect the production of prostanoids

1986 • 11 citations

Anti-Inflammatory Efficacy and Gastrointestinal Irritancy: Comparative 1 Month Repeat Oral Dose Studies in the Rat with Nabumetone, Ibuprofen and Diclofenac

1991 • 9 citations

[Treatment of rheumatic diseases with nabumetone. Results of a study using the drug in 18,046 patients].

1988 • 9 citations

A method for occult blood in faeces using non-carcinogenic reagents.

1971 • 8 citations

[Absent enterohepatic circulation of the active metabolite of nabumetone].

1988 • 8 citations

Interleukin-1 in the Acute Phase Response

1989 • 6 citations

Effect of the antiinflammatory prodrug, nabumetone and its principal active metabolite on rat gastric mucosal, aortic and platelet eicosanoid synthesis, in vitro and ex vivo

1990 • 5 citations

Inhibition of platelet cyclooxygenase by aspirin-like drugs: methods for in vitro and ex vivo assessment.

1979 • 5 citations

Correlation between the rise in acute phase proteins and histological evidence of ulceration in the rat following indomethacin treatment [proceedings].

1979 • 4 citations

Deleted Work

1955 • 0 citations