Optimization of retroviral vector-mediated gene transfer into endothelial cells in vitro.

Culture of Human Endothelial Cells Derived from Umbilical Veins. IDENTIFICATION BY MORPHOLOGIC AND IMMUNOLOGIC CRITERIA

1973 • 6,904 citations

The Pathogenesis of Atherosclerosis — An Update

1986 • 4,951 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.

1990 • 1,465 citations

Identification and isolation of endothelial cells based on their increased uptake of acetylated-low density lipoprotein.

1984 • 1,249 citations

Use of a recombinant retrovirus to study post-implantation cell lineage in mouse embryos.

1986 • 1,118 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

1986 • 828 citations

Site-Specific Gene Expression in Vivo by Direct Gene Transfer into the Arterial Wall

1990 • 573 citations

Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes.

1991 • 489 citations

Rapid Cell Culture Assay Technique for Murine Leukaemia Viruses

1971 • 360 citations

Enhancement and inhibition of avian sarcoma viruses by polycations and polyanions

1969 • 351 citations

Implantation of Vascular Grafts Lined with Genetically Modified Endothelial Cells

1989 • 342 citations

MEASUREMENT OF ACTIVITY OF SINGLE MOLECULES OF β-D-GALACTOSIDASE

1961 • 339 citations

Gene Transfer by Retrovirus Vectors Occurs Only in Cells That Are Actively Replicating at the Time of Infection

1990 • 273 citations

Type 1 plasminogen activator inhibitor gene: functional analysis and glucocorticoid regulation of its promoter.

1988 • 222 citations

Retroviral vectors containing putative internal ribosome entry sites: development of a polycistronic gene transfer system and applications to human gene therapy

1992 • 211 citations

A Membrane Effect of Basic Polymers dependent on Molecular Size

1967 • 207 citations

Development of a high-titer retrovirus producer cell line capable of gene transfer into rhesus monkey hematopoietic stem cells.

1990 • 186 citations

Low level in vivo gene transfer into the arterial wall through a perforated balloon catheter.

1992 • 159 citations

Protamine sulfate as an effective alternative to polybrene in retroviral-mediated gene-transfer: implications for human gene therapy

1989 • 149 citations

Genome structure of incomplete particles of adenovirus

1976 • 145 citations

High-Level Recombinant Gene Expression in Rabbit Endothelial Cells Transduced by Retroviral Vectors

1989 • 139 citations

Long-term expression of human adenosine deaminase in vascular smooth muscle cells of rats: a model for gene therapy.

1992 • 134 citations

Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent

1989 • 129 citations

Autologous transplantation of canine long-term marrow culture cells genetically marked by retroviral vectors

1992 • 125 citations

Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia B.

1991 • 116 citations

Hepatic gene transfer in animals using retroviruses containing the promoter from the gene for phosphoenolpyruvate carboxykinase.

1990 • 106 citations

Differential muscarinic receptor mRNA expression by freshly isolated and cultured bovine aortic endothelial cells.

1992 • 102 citations

Induction of Morphologic Differentiation of Endothelial Cells in Culture

1989 • 98 citations

Genetically engineered endothelial cells remain adherent and viable after stent deployment and exposure to flow in vitro.

1992 • 97 citations

Production of high-titer helper virus-free retroviral vectors by cocultivation of packaging cells with different host ranges

1991 • 78 citations

Enhancing effect of diethylaminoethyl-dextran on the focus-forming titer of a murine sarcoma virus (Harvey strain)

1968 • 78 citations

Rapid colorimetric quantification of PCR-amplified DNA.

1991 • 70 citations

Induction of Morphologic Differentiation of Endothelial Cells in Culture.

1989 • 63 citations

Correction of CD18-Deficient Lymphocytes by Retrovirus-Mediated Gene Transfer

1990 • 60 citations

Retroviral-mediated transfer and amplification of a functional human factor VIII gene

1990 • 56 citations

Improved retroviral transfer of genes into canine hematopoietic progenitor cells kept in long-term marrow culture

1989 • 55 citations

Seeding of intravascular stents with genetically engineered endothelial cells

1990 • 53 citations

Effect of Polycations on Sensitivity of BALB/3T3 Cells to Murine Leukemia and Sarcoma Virus Infectivity

1971 • 47 citations

Expression of a Prokaiyotic Gene in Cultured Lung Endothelial Cells after Lipofection with a Plasmid Vector

1989 • 44 citations

Gene transfer method for transient gene expression, stable transformation, and cotransformation of suspension cell cultures.

1985 • 41 citations

Expression of an anchored urokinase in the apical endothelial cell membrane. Preservation of enzymatic activity and enhancement of cell surface plasminogen activation.

1992 • 36 citations

Endothelium in Health and Disease

1989 • 32 citations

Calcium Phosphate Mediated Gene Transfer into Established Cell Lines

2003 • 30 citations

Effect of Polycations on Sensitivity of BALB/3T3 Cells to Murine Leukemia and Sarcoma Virus Infectivity

1971 • 27 citations

Efficient gene transfer by sequential treatment of mammalian cells with DEAE-dextran and deoxyribonucleic acid

1989 • 26 citations

Retroviral vector-mediated gene transfer into endothelial cells.

1991 • 17 citations

Transfer of Genes into Human Somatic Cells Using Retrovirus Vectors

1986 • 17 citations

239 The type 1 plasminogen activator inhibitor gene: Functional analysis and glucocorticoid regulation of its promoter

1988 • 14 citations

Respiratory tract gene transfer. Transplantation of genetically modified T-lymphocytes directly to the respiratory epithelial surface.

1991 • 14 citations

Autologous transplantation of canine long-term marrow culture cells genetically marked by retroviral vectors

1992 • 12 citations

Improved retroviral transfer of genes into canine hematopoietic progenitor cells kept in long-term marrow culture

1989 • 8 citations

Gene Transfer Method for Transient Gene Expression, Stable Transformation, and Cotransformation of Suspension Cell Cultures

1985 • 8 citations

Gene Transfer into Hematopoietic Stem Cells

1992 • 8 citations

Retroviral-mediated transfer and amplification of a functional human factor VIII gene

1990 • 1 citations