Biological Effects of C-type Natriuretic Peptide in Human Myofibroblastic Hepatic Stellate Cells

Inositol trisphosphate and calcium signalling

1993 • 6,546 citations

Natriuretic Peptides

1998 • 1,849 citations

The Cellular Basis of Hepatic Fibrosis -- Mechanisms and Treatment Strategies

1993 • 1,444 citations

Cyclin D1 Expression Is Regulated Positively by the p42/p44 and Negatively by the p38/HOG Pathway

1996 • 1,203 citations

Selective Activation of the B Natriuretic Peptide Receptor by C-Type Natriuretic Peptide (CNP)

1991 • 722 citations

Differential activation by atrial and brain natriuretic peptides of two different receptor guanylate cyclases

1989 • 579 citations

Ca2+ current is regulated by cyclic GMP-dependent protein kinase in mammalian cardiac myocytes.

1991 • 475 citations

The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances

1993 • 391 citations

Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.

1989 • 370 citations

Guanylyl cyclase receptors and their endocrine, paracrine, and autocrine ligands

1992 • 346 citations

Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients.

1992 • 338 citations

Book Review Ethical Problems in Dialysis and Transplantation (Developments in Nephrology. Vol. 33.) Edited by Carl M. Kjellstrand and John B. Dossetor. 235 pp., illustrated. Boston, Kluwer Academic, 1992. $108.50. 0-7923-1625-8

1993 • 329 citations

Ring-deleted analogs of atrial natriuretic factor inhibit adenylate cyclase/cAMP system. Possible coupling of clearance atrial natriuretic factor receptors to adenylate cyclase/cAMP signal transduction system.

1990 • 284 citations

Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca ²⁺ entry channel

1999 • 278 citations

Natriuretic peptides inhibit angiotensin II-induced proliferation of rat cardiac fibroblasts by blocking endothelin-1 gene expression.

1995 • 267 citations

Activation-dependent contractility of rat hepatic lipocytes in culture and in vivo.

1993 • 264 citations

Tissue distribution, quantitation and proliferation kinetics of fat-storing cells in carbon tetrachloride–injured rat liver

1991 • 200 citations

Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility.

1995 • 172 citations

Atrial Natriuretic Peptide Inhibits Mitogen-activated Protein Kinase through the Clearance Receptor

1996 • 161 citations

Role of NF-κB in the Antiproliferative Effect of Endothelin-1 and Tumor Necrosis Factor-α in Human Hepatic Stellate Cells

1998 • 158 citations

The agonist-sensitive calcium pool in the pancreatic acinar cell. Activation of plasma membrane Ca2+ influx mechanism.

1987 • 142 citations

Mitogenic effect of transforming growth factor-beta 1 on human Ito cells in culture: evidence for mediation by endogenous platelet-derived growth factor.

1993 • 127 citations

Ito cell contraction in response to endothelin-1 and substance P

1993 • 122 citations

cGMP produced in response to ANP and CNP regulates proliferation and differentiation of osteoblastic cells

1996 • 122 citations

Isolation and functional expression of the human atrial natriuretic peptide clearance receptor cDNA

1990 • 113 citations

Autocrine regulation of rat chondrocyte proliferation by natriuretic peptide C and its receptor, natriuretic peptide receptor-B.

1994 • 113 citations

Endothelin action in rat liver. Receptors, free Ca2+ oscillations, and activation of glycogenolysis.

1991 • 110 citations

Growth inhibitory properties of endothelin-1 in human hepatic myofibroblastic Ito cells. An endothelin B receptor-mediated pathway.

1995 • 110 citations

Cyclic-GMP-Dependent Protein Kinase Inhibits the Ras/Mitogen-Activated Protein Kinase Pathway

1998 • 109 citations

Cyclic GMP‐mediated inhibition of L‐type Ca²⁺ channel activity by human natriuretic peptide in rabbit heart cells

1995 • 104 citations

Growth inhibitory properties of endothelin-1 in activated human hepatic stellate cells: a cyclic adenosine monophosphate-mediated pathway. Inhibition of both extracellular signal-regulated kinase and c-Jun kinase and upregulation of endothelin B receptors.

1996 • 103 citations

Platelet-derived Growth Factor-BB and Thrombin Generate Positive and Negative Signals for Human Hepatic Stellate Cell Proliferation

1998 • 103 citations

A role for phosphorylation and degradation in the control of NF-κB activity

1995 • 99 citations

Reciprocal Antagonism Coordinates C-type Natriuretic Peptide and Mitogen-signaling Pathways in Fibroblasts

1999 • 98 citations

Mitogenic effect of transforming growth factor-β1 on human ito cells in culture: Evidence for mediation by endogenous platelet-derived growth factor

1993 • 94 citations

Arginine vasopressin induces contraction and stimulates growth of cultured human hepatic stellate cells

1997 • 85 citations

Atrial Natriuretic Peptide Induces the Expression of MKP-1, a Mitogen-activated Protein Kinase Phosphatase, in Glomerular Mesangial Cells

1996 • 79 citations

1α,25-Dihydroxy-vitamin-D3-induced Store-operated Ca2+ Influx in Skeletal Muscle Cells

1998 • 69 citations

The mitogenic effect of platelet-derived growth factor in human hepatic stellate cells requires calcium influx

1995 • 66 citations

C-type natriuretic peptide inhibits mesangial cell proliferation and matrix accumulation in vivo

1998 • 55 citations

Quantitative analysis of proliferating sinusoidal cells in dimethylnitrosamine-induced cirrhosis

1992 • 45 citations

Inhibition by glucagon of the cGMP-inhibited low-Km cAMP phosphodiesterase in heart is mediated by a pertussis toxin-sensitive G-protein.

1992 • 44 citations

Astrocyte Progression from G1 to S Phase of the Cell Cycle Depends upon Multiple Protein Interaction

1998 • 43 citations

Effect of adrenomedullin on hepatic pericytes (stellate cells) of the rat

1994 • 42 citations

Atrial natriuretic peptide inhibits endothelin-1-induced activation of JNK in glomerular mesangial cells

1998 • 42 citations

Differential gene expression of the three natriuretic peptides and natriuretic peptide receptor subtypes in human liver.

1997 • 38 citations

Atrial natriuretic peptide inhibits growth of hepatoblastoma (HEP G2) cells by means of activation of clearance receptors

1993 • 35 citations

Biological Receptors Mediate Anti-proliferative Action of Atrial Natriuretic Peptide in Cultured Mesangial Cells

1993 • 30 citations

Blunted natriuresis and abnormal systemic hemodynamic responses to C-type and brain natriuretic peptides in rats with cirrhosis

1995 • 26 citations

Arachidonic Acid Drives Mini-glucagon Action in Cardiac Cells

1997 • 23 citations

Hepatic Stellate Cells and Intrahepatic Modulation of Portal Pressure

1998 • 20 citations

Alcohol Stimulates the Expression of L-Type Voltage-Operated Ca2+Channels in Hepatic Stellate Cells

1998 • 17 citations

Prolonged antagonism of α1-Adrenergic vasoconstriction in the rat liver by atrial natriuretic peptide

1995 • 17 citations

Relaxing effect of interleukin-1 on rat cultured Ito cells

1997 • 15 citations

Increase in the number of atrial natriuretic hormone receptors in regenerating rat liver.

1991 • 15 citations

Stimulation of cyclic guanosine monophosphate production by natriuretic peptide in human biliary cells

1998 • 14 citations

Inhibition of the sarcolemmal Ca2+ pump in embryonic chick heart cells by mini-glucagon

1995 • 12 citations

Inhibition of platelet-derived growth factor receptor tyrosine kinase by atrial natriuretic peptide

1997 • 9 citations