Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

[21] Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction

1987 • 5,745 citations

The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains

1988 • 5,115 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Patterns of Amino Acids near Signal‐Sequence Cleavage Sites

1983 • 2,290 citations

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

1985 • 2,257 citations

The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA

1978 • 1,055 citations

A membrane form of guanylate cyclase is an atrial natriuretic peptide receptor

1989 • 996 citations

Mechanisms for the incorporation of proteins in membranes and organelles.

1982 • 875 citations

Cyclic GMP synthesis and function.

1987 • 871 citations

The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins

1985 • 845 citations

[71] Use of eukaryotic expression technology in the functional analysis of cloned genes

1987 • 834 citations

Roles of G protein subunits in transmembrane signalling

1988 • 794 citations

ADENYL CYCLASE AS AN ADRENERGIC RECEPTOR*

1967 • 682 citations

Atrial natriuretic factor selectively activates particulate guanylate cyclase and elevates cyclic GMP in rat tissues.

1984 • 676 citations

Purification and Sequence Analysis of Bioactive Atrial Peptides (Atriopeptins)

1984 • 525 citations

Atrial natriuretic factor elicits an endothelium-independent relaxation and activates particulate guanylate cyclase in vascular smooth muscle.

1984 • 495 citations

Atrial natriuretic peptide clearance receptor. Complete sequence and functional expression of cDNA clones.

1988 • 479 citations

Genes-in-Pieces Revisited

1985 • 362 citations

Effect of native and synthetic atrial natriuretic factor on cyclic GMP

1984 • 359 citations

Co-purification of an atrial natriuretic factor receptor and particulate guanylate cyclase from rat lung.

1986 • 338 citations

Identification of Human Uromodulin as the Tamm-Horsfall Urinary Glycoprotein

1987 • 273 citations

Membrane guanylate cyclase is a cell-surface receptor with homology to protein kinases

1988 • 258 citations

Molecular analysis of signal transduction by growth factors

1988 • 224 citations

Identification of multiple binding sites for atrial natriuretic factor by affinity cross-linking in cultured endothelial cells.

1986 • 224 citations

Coexistence of Guanylate Cyclase and Atrial Natriuretic Factor Receptor in a 180-kD Protein

1987 • 218 citations

Two distinct forms of receptors for atrial natriuretic factor in bovine adrenocortical cells. Purification, ligand binding, and peptide mapping.

1987 • 199 citations

Cassette of Eight Exons Shared by Genes for LDL Receptor and EGF Precursor

1985 • 185 citations

The primary structure of the 70 kDa subunit of bovine soluble guanylate cyclase

1988 • 141 citations

Atrial natriuretic factor R1 receptor from bovine adrenal zona glomerulosa: purification, characterization, and modulation by amiloride

1988 • 132 citations

Covalent coupling of a resact analogue to guanylate cyclase.

1986 • 109 citations

The structure of the human c-fes/fps proto-oncogene.

1985 • 106 citations

Identification and characterization of three distinct atrial natriuretic factor receptors. Evidence for tissue-specific heterogeneity of receptor subtypes in vascular smooth muscle, kidney tubular epithelium, and Leydig tumor cells by ligand binding, photoaffinity labeling, and tryptic proteolysis.

1988 • 100 citations

Identification of a receptor for atrial natriuretic factor in rabbit aorta membranes by affinity cross-linking.

1985 • 93 citations

Identification of the receptor for atrial natriuretic factor on cultured vascular cells.

1985 • 90 citations

The biochemistry and molecular biology of atrial natriuretic factor

1985 • 83 citations

Photoaffinity labeling of atrial natriuretic factor receptor in bovine and rat adrenal cortical membranes

1985 • 77 citations

Channel families in the brain

1987 • 58 citations

A linear analog of atrial natriuretic peptide (ANP) discriminates guanylate cyclase-coupled ANP receptors from non-coupled receptors.

1988 • 55 citations

ANF stimulation of detergent‐dispersed particulate guanylate cyclase from bovine adrenal cortex

1986 • 46 citations

Functional heterogeneity of atrial natriuretic factor receptor in bovine adrenal zona glomerulosa is explained by an amiloride-sensitive high affinity molecular complex.

1987 • 43 citations

Sea urchin sperm guanylate cyclase antibody. Cross-reactivity various rat tissue guanylate cyclases.

1978 • 35 citations

Molecular characteristics of receptors for atrial natriuretic factor.

1986 • 11 citations

Sea urchin sperm guanylate cyclase antibody. Cross-reactivity various rat tissue guanylate cyclases.

1978 • 5 citations