Sites of Action of Protein Kinase C and Phosphatidylinositol 3-Kinase Are Distinct in Oxidized Low Density Lipoprotein-induced Macrophage Proliferation

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Beyond Cholesterol

1989 • 6,533 citations

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

1994 • 3,249 citations

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Book ReviewAmbulatory Pediatric Care

1989 • 2,075 citations

Requirement for Phosphatidylinositol-3 Kinase in the Prevention of Apoptosis by Nerve Growth Factor

1995 • 1,400 citations

Protein kinase C isoenzymes: divergence in signal transduction?

1993 • 1,237 citations

Comparison of three actin-coding sequences in the mouse; Evolutionary relationships between the actin genes of warm-blooded vertebrates

1986 • 678 citations

Molecular physiology of granulocyte-macrophage colony-stimulating factor

1991 • 598 citations

Cell proliferation in human coronary arteries.

1990 • 532 citations

Molecular physiology of granulocyte-macrophage colony-stimulating factor

1991 • 505 citations

Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase.

1994 • 443 citations

Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5

1993 • 404 citations

Macrophage and smooth muscle cell proliferation in atherosclerotic lesions of WHHL and comparably hypercholesterolemic fat-fed rabbits.

1990 • 333 citations

Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5

1993 • 318 citations

Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes.

1985 • 257 citations

Lysophosphatidylcholine plays an essential role in the mitogenic effect of oxidized low density lipoprotein on murine macrophages.

1994 • 196 citations

Phosphatidylinositol kinase activity associates with viral p60src protein.

1989 • 194 citations

T-Cell Activation Signals and Human T-Cell Leukemia Virus Type I-Encoded p40^x Protein Activate the Mouse Granulocyte-Macrophage Colony-Stimulating Factor Gene Through a Common DNA Element

1988 • 171 citations

Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-α and GM-CSF

1998 • 160 citations

Granulocyte-macrophage colony-stimulating factor (GM-CSF) and granulocyte colony-stimulating factor (G-CSF): Receptor biology, signal transduction, and neutrophil activation

1992 • 138 citations

Oxidized LDL Can Induce Macrophage Survival, DNA Synthesis, and Enhanced Proliferative Response to CSF-1 and GM-CSF

1999 • 136 citations

Activation of the Granulocyte-Macrophage Colony-Stimulating Factor Promoter in T Cells Requires Cooperative Binding of Elf-1 and AP-1 Transcription Factors

1994 • 135 citations

The granulocyte-macrophage colony-stimulating factor promoter cis-acting element CLE0 mediates induction signals in T cells and is recognized by factors related to AP1 and NFAT.

1993 • 131 citations

Bacterial lipopolysaccharide induces the association and coordinate activation of p53/56lyn and phosphatidylinositol 3-kinase in human monocytes.

1996 • 130 citations

Induction of murine macrophage growth by modified LDLs.

1993 • 121 citations

Two Intracellular Signaling Pathways for Activation of Protein Kinase C Are Involved in Oxidized Low-Density Lipoprotein–Induced Macrophage Growth

1997 • 103 citations

The Scavenger Receptor Serves as a Route for Internalization of Lysophosphatidylcholine in Oxidized Low Density Lipoprotein-induced Macrophage Proliferation

1996 • 100 citations

Cytokine-Induced Protein Kinase B Activation and Bad Phosphorylation Do Not Correlate with Cell Survival of Hemopoietic Cells

1999 • 91 citations

Granulocyte-Macrophage Colony-stimulating Factor-activated Signaling Pathways in Human Neutrophils

1999 • 87 citations

Phosphatidylinositol 3-Kinase Is Involved in the Induction of Macrophage Growth by Oxidized Low Density Lipoprotein

1998 • 84 citations

Oxidized Low Density Lipoprotein Suppresses Activation of NFκB in Macrophages via a Pertussis Toxin-sensitive Signaling Mechanism

1995 • 78 citations

Lysophosphatidylcholine Potentiates the Mitogenic Activity of Modified LDL for Human Monocyte–Derived Macrophages

1996 • 75 citations

Phosphatidylinositol 3-kinase activation in normal human B lymphocytes.

1996 • 72 citations

Induction of Murine Macrophage Growth by Oxidized Low Density Lipoprotein Is Mediated by Granulocyte Macrophage Colony-stimulating Factor

1998 • 72 citations

Acetylated low density lipoprotein reduces its ligand activity for the scavenger receptor after interaction with reconstituted high density lipoprotein.

1994 • 67 citations

Foam cells of the rabbit atherosclerotic plaque arrested in metaphase by colchicine show a macrophage phenotype

1991 • 65 citations

Involvement of JAK2, but not PI 3-kinase/Akt and MAP kinase pathways, in anti-apoptotic signals of GM-CSF in human eosinophils

1999 • 62 citations

Transcriptional regulation of cytokine genes in nontransformed T cells. Apparent constitutive signals in run-on assays can be caused by repeat sequences.

1991 • 56 citations

Species difference in cholesteryl ester cycle and HDL-induced cholesterol efflux from macrophage foam cells.

1994 • 56 citations

Cross‐linking of apolipoproteins is involved in a loss of the ligand activity of high density lipoprotein upon Cu²⁺‐mediated oxidation

1992 • 55 citations

A Modification of Apolipoprotein B Accounts for Most of the Induction of Macrophage Growth by Oxidized Low Density Lipoprotein

1999 • 50 citations

Chemical cross-linking alters high-density lipoprotein to be recognized by a scavenger receptor in rat peritoneal macrophages

1991 • 44 citations

In Vitro–Differentiated Embryonic Stem Cell Macrophages

1998 • 38 citations

Induction of Macrophage DNA Synthesis by phorbol esters

1981 • 36 citations

Granulocyte-macrophage colony-stimulating factor and IL-5 activate mitogen-activated protein kinase through Jak2 kinase and phosphatidylinositol 3-kinase inhuman eosinophils

1997 • 32 citations

Interaction of GM-CSF and IL-3 with the common β-chain of their receptors

1995 • 32 citations

Glucocorticoid Inhibits Oxidized LDL-Induced Macrophage Growth by Suppressing the Expression of Granulocyte/Macrophage Colony-Stimulating Factor

1999 • 31 citations

Inducible and non-inducible factors co-operatively activate the GM-CSF promoter by interacting with adjacent DNA motifs

1990 • 31 citations

Cis-acting DNA Elements of Mouse Granulocyte/Macrophage Colony-stimulating Factor Gene Responsive to Oxidized Low Density Lipoprotein

1999 • 25 citations

Lipoprotein(a) induces cell growth in rat peritoneal macrophages through inhibition of transforming growth factor-β activation

1996 • 24 citations

Recombinant granulocyte-macrophage colony-stimulating factor increases adenylate cyclase activity in murine peritoneal macrophages.

1989 • 21 citations

Endocytosed Lysophosphatidylcholine, Through the Scavenger Receptor, Plays an Essential Role in Oxidized Low-Density Lipoprotein-Induced Macrophage Proliferation

1998 • 17 citations