Varying cecal bacterial loads influences colitis and gastritis in HLA-B27 transgenic rats

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice

1990 • 2,321 citations

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1993 • 1,762 citations

Wadsworth anaerobic bacteriology manual

1980 • 1,490 citations

Resident Enteric Bacteria Are Necessary for Development of Spontaneous Colitis and Immune System Activation in Interleukin-10-Deficient Mice

1998 • 1,451 citations

Antibodies to interleukin 12 abrogate established experimental colitis in mice.

1995 • 1,338 citations

The germfree state prevents development of gut and joint inflammatory disease in HLA-B27 transgenic rats.

1994 • 1,128 citations

Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human β2m: An animal model of HLA-B27-associated human disorders

1990 • 1,001 citations

Normal luminal bacteria, especially Bacteroides species, mediate chronic colitis, gastritis, and arthritis in HLA-B27/human beta2 microglobulin transgenic rats.

1996 • 795 citations

Effect of faecal stream diversion on recurrence of Crohn's disease in the neoterminal ileum

1991 • 755 citations

Double blind, placebo controlled trial of metronidazole in Crohn's disease.

1991 • 543 citations

Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria.

1996 • 437 citations

CD4+ T Cells Reactive to Enteric Bacterial Antigens in Spontaneously Colitic C3H/HeJBir Mice: Increased T Helper Cell Type 1 Response and Ability to Transfer Disease

1998 • 393 citations

T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment.

1997 • 334 citations

Analysis of intestinal lymphocytes in mouse colitis mediated by transfer of CD4+, CD45RBhigh T cells to SCID recipients.

1997 • 320 citations

Mucins and inflammatory bowel disease

2000 • 316 citations

Mechanisms of acute and chronic intestinal inflammation induced by indomethacin

1993 • 315 citations

Role of appendix in the development of inflammatory bowel disease in TCR-alpha mutant mice.

1996 • 265 citations

Susceptibility to inflammatory disease in HLA-B27 transgenic rat lines correlates with the level of B27 expression.

1993 • 239 citations

Hepatic Steatosis After Intestinal Bypass—Prevention and Reversal by Metronidazole, Irrespective of Protein-Calorie Malnutrition

1982 • 233 citations

Long-term treatment of ulcerative colitis with ciprofloxacin: A prospective, double-blind, placebo-controlled study

1998 • 232 citations

Significance of systemic endotoxaemia in inflammatory bowel disease.

1995 • 228 citations

Hepatic inflammation in rats with experimental small intestinal bacterial overgrowth

1990 • 211 citations

Role of the faecal stream in the maintenance of Crohn's colitis.

1985 • 203 citations

Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline

1991 • 171 citations

The influence of normal microbial flora on the development of chronic mucosal inflammation

1997 • 168 citations

Spontaneously colitic C3H/HeJBir mice demonstrate selective antibody reactivity to antigens of the enteric bacterial flora.

1997 • 158 citations

Split ileostomy and ileocolostomy for Crohn's disease of the colon and ulcerative colitis: a 20 year survey.

1983 • 140 citations

Production of experimental ulcerative colitis in gnotobiotic guinea pigs with simplified microflora

1981 • 128 citations

Hepatic effects of jejunoileal bypass for morbid obesity

1974 • 120 citations

Bacteriological studies of experimental ulcerative colitis

1979 • 108 citations

The Obligate Anaerobic Faecal Flora of Patients with Crohn's Disease and Their First-Degree Relatives

1988 • 105 citations

Incrimination of anaerobic bacteria in the induction of experimental colitis

1997 • 104 citations

Bacteroides fragilis enterotoxin modulates epithelial permeability and bacterial internalization by HT-29 enterocytes

1996 • 101 citations

Microbial factors in chronic intestinal inflammation

1996 • 77 citations

Selected Bacterial Antibodies in Crohn's Disease and Ulcerative Colitis

1983 • 72 citations

NUTRITIONAL ISSUES IN INFLAMMATORY BOWEL DISEASE

1998 • 69 citations

Evidence for peptidoglycan absorption in rats with experimental small bowel bacterial overgrowth

1991 • 68 citations

Colitis and colonic mucosal barrier dysfunction.

1995 • 58 citations

Relation between concentrations of metronidazole and Bacteroides spp in faeces of patients with Crohn's disease and healthy individuals.

1981 • 54 citations

Alteration of a polyclonal to an oligoclonal immune response to cecal aerobic bacterial antigens in TCRα mutant mice with inflammatory bowel disease

1996 • 50 citations

Reactivation of arthritis induced by small bowel bacterial overgrowth in rats: role of cytokines, bacteria, and bacterial polymers

1995 • 49 citations

Fecal diversion in the management of Crohn's disease of the colon

1993 • 49 citations

Endotoxaemia and cytokine production in experimental colitis

1995 • 38 citations

A Rat Model of Ileal Pouch-Rectal Anastomosis

1998 • 28 citations

Antibodies detectable by counterimmunoelectrophoresis against Bacteroides antigens in serum of patients with inflammatory bowel disease

1979 • 20 citations

Experimental colitis in rats induces low-grade endotoxinemia without hepatobiliary abnormalities

1994 • 17 citations

Selective vs. broad spectrum antibiotics in the prevention and treatment of experimental colitis in two rodent models

1998 • 16 citations

Lymphocytotoxic and microbial antibodies in Crohn's disease and matched controls

1981 • 11 citations

Normal bacteria stimulate colonic, gastric and systemic inflammation in HLA-B27/β2-m transgenic rats

1995 • 9 citations

A rat model of ileal pouch-rectal anastomosis

2007 • 8 citations