T cell receptor-alpha beta-deficient mice fail to develop colitis in the absence of a microbial environment.

Interleukin-10-deficient mice develop chronic enterocolitis

1993 • 4,225 citations

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

1992 • 2,969 citations

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

1993 • 1,762 citations

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

1994 • 1,129 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

Phenotypically distinct subsets of CD4⁺ T cells induce or protect from chronic intestinal inflammation in C. B-17 scid mice

1993 • 1,064 citations

Tolerance exists towards resident intestinal flora but is broken in active inflammatory bowel disease (IBD)

1995 • 965 citations

Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice

1993 • 732 citations

Lymphoid Development in Mice Congenitally Lacking T Cell Receptor αβ-Expressing Cells

1992 • 371 citations

Cytokine imbalance and autoantibody production in T cell receptor-alpha mutant mice with inflammatory bowel disease.

1996 • 224 citations

Chronic intestinal inflammation: An unexpected outcome in cytokine or T cell receptor mutant mice

1993 • 193 citations

Severe colitis in mice with aberrant thymic selection

1995 • 186 citations

Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells

1994 • 167 citations

T cells, but not B cells, are required for bowel inflammation in interleukin 2-deficient mice.

1995 • 149 citations

Evidence that CD4⁺, but not CD8⁺ T cells are responsible for murine interleukin‐2‐deficient colitis

1995 • 144 citations

Germinal center formation, immunoglobulin class switching, and autoantibody production driven by "non alpha/beta" T cells.

1996 • 123 citations

Does dietary fibre stimulate intestinal epithelial cell proliferation in germ free rats?

1989 • 108 citations

γδ T cell help of B cells is induced by repeated parasitic infection, in the absence of other T cells

1996 • 75 citations

Products of enteropathogenic Escherichia coli inhibit lymphocyte activation and lymphokine production

1995 • 71 citations

Germinal center formation in mice lacking αβ T cells

1996 • 48 citations

Gut‐homing CD4⁺ T cell receptor αβ⁺ T cells in the pathogenesis of murine inflammatory bowel disease

1994 • 44 citations

A gut‐homing, oligoclonal CD4⁺ T cell population in severe‐combined immunodeficient mice expressing a rearranged, transgenic class I‐restricted αβ T cell receptor

1995 • 18 citations

Unidirectional air flow surgical isolator for hysterectomy of mice

1973 • 10 citations