Monoclonal Antibody-Mediated CD200 Receptor Signaling Suppresses Macrophage Activation and Tissue Damage in Experimental Autoimmune Uveoretinitis

Alternative activation of macrophages

2003 • 5,952 citations

Pattern Recognition Receptors

2002 • 1,139 citations

Down-Regulation of the Macrophage Lineage Through Interaction with OX2 (CD200)

2000 • 983 citations

A Phase II Randomized Double-Masked Trial of Pegaptanib, an Anti–Vascular Endothelial Growth Factor Aptamer, for Diabetic Macular Edema

2005 • 594 citations

Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells

1999 • 558 citations

A new model of autoimmune disease. Experimental autoimmune uveoretinitis induced in mice with two different retinal antigens.

1988 • 451 citations

CD200 and membrane protein interactions in the control of myeloid cells

2002 • 406 citations

Lymphoid/Neuronal Cell Surface OX2 Glycoprotein Recognizes a Novel Receptor on Macrophages Implicated in the Control of Their Function

2000 • 386 citations

Molecular Mechanisms of CD200 Inhibition of Mast Cell Activation

2004 • 227 citations

Constitutive Retinal CD200 Expression Regulates Resident Microglia and Activation State of Inflammatory Cells during Experimental Autoimmune Uveoretinitis

2002 • 214 citations

Regulation of Myeloid Cell Function through the CD200 Receptor

2006 • 214 citations

Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype.

2000 • 117 citations

CD200 Immunoadhesin Suppresses Collagen-Induced Arthritis in Mice

2001 • 104 citations

Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism.

1997 • 98 citations

Retinal microenvironment controls resident and infiltrating macrophage function during uveoretinitis.

2002 • 95 citations

Control of myeloid activity during retinal inflammation

2003 • 93 citations

Dok-1 and Dok-2 are negative regulators of lipopolysaccharide-induced signaling

2005 • 88 citations

Putting the brakes on innate immunity: a regulatory role for CD200?

2001 • 78 citations

Distribution of OX2 antigen and OX2 receptor within retina.

2001 • 75 citations

Immunomodulation of experimental autoimmune uveoretinitis: A model of tolerance induction with retinal antigens

1994 • 73 citations

The leukocyte/neuron cell surface antigen OX2 binds to a ligand on macrophages

1997 • 72 citations

Transplant tolerance modifying antibody to CD200 receptor, but not CD200, alters cytokine production profile from stimulated macrophages

2001 • 48 citations

A Selective Role for the TNF p55 Receptor in Autocrine Signaling following IFN-γ Stimulation in Experimental Autoimmune Uveoretinitis

2005 • 48 citations

Blocking CD200-CD200 receptor axis augments NOS-2 expression and aggravates experimental autoimmune uveoretinitis in Lewis rats

2004 • 47 citations

Transplant tolerance modifying antibody to CD200 receptor, but not CD200, alters cytokine production profile from stimulated macrophages

2001 • 44 citations

Enhanced Tolerance to Autoimmune Uveitis in CD200-Deficient Mice Correlates with a Pronounced Th2 Switch in Response to Antigen Challenge

2005 • 33 citations

Interphotoreceptor Retinoid Binding Protein Peptide-induced Uveitis in B10.RIII Mice: Characterization of Disease Parameters and Immunomodulation

2001 • 27 citations