Cytoplasmically Anchored Plakoglobin Induces a WNT-like Phenotype inXenopus

Normal Table of Xenopus Laevis (Daudin)

1958 • 4,561 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

XTcf-3 Transcription Factor Mediates β-Catenin-Induced Axis Formation in Xenopus Embryos

1996 • 1,827 citations

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

1982 • 1,635 citations

A new member of the frizzled family from Drosophila functions as a Wingless receptor

1996 • 1,489 citations

Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly

1996 • 1,382 citations

Association of the APC Gene Product with β-Catenin

1993 • 1,215 citations

Association of the APC Tumor Suppressor Protein with Catenins

1993 • 1,202 citations

The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3.

1996 • 1,156 citations

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

1995 • 1,025 citations

Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice.

1994 • 969 citations

Nuclear localization of β-catenin by interaction with transcription factor LEF-1

1996 • 864 citations

Wnt genes

1992 • 799 citations

Molecular cloning of cDNA for rat liver gap junction protein.

1986 • 715 citations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

1992 • 684 citations

Signal transduction through beta-catenin and specification of cell fate during embryogenesis.

1996 • 663 citations

Xenopus embryos regulate the nuclear localization of XMyoD.

1994 • 648 citations

Overexpression of cadherins and underexpression of ?-catenin inhibit dorsal mesoderm induction in early Xenopus embryos

1994 • 647 citations

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.

1994 • 647 citations

Structural basis for DNA bending by the architectural transcription factor LEF-1

1995 • 574 citations

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling.

1995 • 545 citations

Expression cloning of Siamois, a xenopus homeobox gene expressed in dorsal-vegetal cells of blastulae and able to induce a complete secondary axis

1995 • 521 citations

β-catenin translocation into nuclei demarcates the dorsalizing centers in frog and fish embryos

1996 • 516 citations

Plakoglobin: A protein common to different kinds of intercellular adhering junctions

1986 • 508 citations

Glycogen synthase kinase-3 and dorsoventral patterning in Xenopus embryos

1995 • 492 citations

The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin

1990 • 474 citations

A whole-mount immunocytochemical analysis of the expression of the intermediate filament protein vimentin in Xenopus

1989 • 441 citations

wingless signaling acts through zeste-white 3, the drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

1992 • 425 citations

wingless signal and Zeste-white 3 kinase trigger opposing changes in the intracellular distribution of Armadillo

1994 • 423 citations

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

1994 • 405 citations

The roles of catenins in the cadherin-mediated cell adhesion: functional analysis of E-cadherin-alpha catenin fusion molecules.

1994 • 398 citations

The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties.

1992 • 385 citations

Spatial expression of the Drosophila segment polarity gene armadillo is posttranscriptionally regulated by wingless

1990 • 374 citations

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart.

1996 • 335 citations

A nodal-related gene defines a physical and functional domain within the Spemann organizer

1995 • 332 citations

Embryonic Heart and Skin Defects in Mice Lacking Plakoglobin

1996 • 323 citations

The APC Protein and E-cadherin Form Similar but Independent Complexes with α-Catenin, β-Catenin, and Plakoglobin

1995 • 315 citations

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling.

1996 • 292 citations

A truncated beta-catenin disrupts the interaction between E-cadherin and alpha-catenin: a cause of loss of intercellular adhesiveness in human cancer cell lines.

1994 • 284 citations

Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion.

1993 • 249 citations

Regulation of Spemann organizer formation by the intracellular kinase Xgsk-3

1995 • 233 citations

Cytoskeleton—membrane interactions

1996 • 231 citations

Molecular cloning and amino acid sequence of human plakoglobin, the common junctional plaque protein.

1989 • 223 citations

The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm

1996 • 211 citations

Induction of a secondary body axis in Xenopus by antibodies to beta-catenin.

1993 • 205 citations

Biological activity of soluble wingless protein in cultured Drosophila imaginal disc cells

1994 • 194 citations

Deletion of an Amino-Terminal Sequence Stabilizes β-Catenin In Vivo and Promotes Hyperphosphorylation of the Adenomatous Polyposis Coli Tumor Suppressor Protein

1996 • 186 citations

Dorsalizing and neuralizing properties of Xdsh, a maternally expressed Xenopus homolog of dishevelled

1995 • 185 citations

Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage

1993 • 178 citations

Selective disruption of E-cadherin function in early Xenopus embryos by a dominant negative mutant

1994 • 176 citations

Wnt genes and vertebrate development

1994 • 173 citations

Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin.

1995 • 166 citations

Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin

1995 • 144 citations

Desmosomal Cadherin Binding Domains of Plakoglobin

1996 • 122 citations

A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates β-catenin but its zygotic expression is not essential for the regulation of Armadillo

1997 • 119 citations

The body language of cells: The intimate connection between cell adhesion and behavior

1995 • 112 citations

The binding of plakoglobin to desmosomal cadherins: patterns of binding sites and topogenic potential.

1996 • 96 citations

Vimentin’s tail interacts with actin-containing structures in vivo

1994 • 72 citations

Cytoplasmic retention of Xenopus nuclear factor 7 before the mid blastula transition uses a unique anchoring mechanism involving a retention domain and several phosphorylation sites

1994 • 64 citations

腺腫性結腸ポリープ癌抑制遺伝子のショウジョウバエ相同体はβ‐カテニンをダウンレギュレートするが,その接合体発現はアルマジロ蛋白質の調節に必須ではない

1997 • 62 citations

Tissue specific nuclear antigens in the germinal vesicle ofXenopus laevis oocytes

1981 • 59 citations

Functional Conservation of the Wnt Signaling Pathway Revealed by Ectopic Expression of Drosophila dishevelled in Xenopus

1995 • 58 citations

Identification of a Hydra homologue of the β-catenin/plakoglobin/armadillo gene family

1996 • 50 citations

Localizing the adhesive and signaling functions of plakoglobin

1997 • 50 citations

Clonal analysis of the late flowering fca mutant of Arabidopsis thaliana: cell fate and cell autonomy

1996 • 47 citations

Differential accumulation of oocyte nuclear proteins by embryonic nuclei ofXenopus

1987 • 45 citations

Wnt signalling goes nuclear

1997 • 42 citations

Disruption of intermediate filament organization leads to structural defects at the intersomite junction in Xenopus myotomal muscle

1995 • 36 citations

Automatic Microinjector for Amphibian Oocytes, Eggs, and Embryonic Blastomeres

1993 • 2 citations