Glucagon‐like peptide‐1(7–36) amide is a new incretin/enterogastrone candidate

A new method for predicting signal sequence cleavage sites

1986 • 4,629 citations

GLUCAGON-LIKE PEPTIDE-1 7-36: A PHYSIOLOGICAL INCRETIN IN MAN

1987 • 1,845 citations

Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line.

1987 • 830 citations

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

1987 • 814 citations

The incretin concept today

1979 • 730 citations

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing.

1986 • 686 citations

Post-Translational Proteolysis in Polypeptide Hormone Biosynthesis

1982 • 590 citations

Truncated glucagon‐like peptide I, an insulin‐releasing hormone from the distal gut

1987 • 566 citations

Exon duplication and divergence in the human preproglucagon gene

1983 • 558 citations

Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

1986 • 475 citations

Effect of Truncated Glucagon-Like Peptide-1 [Proglucagon-(78–107) amide] on Endocrine Secretion from Pig Pancreas, Antrum, and Nonantral Stomach

1988 • 391 citations

Entero-Insular Axis

1969 • 366 citations

Distribution of glucagonlike peptide I (GLP‐I), glucagon, and glicentin in the rat brain: An immunocytochemical study

1988 • 325 citations

Glucagon-like peptide-1 but not glucagon-like peptide-2 stimulates insulin release from isolated rat pancreatic islets

1985 • 303 citations

Glucagonlike Peptide I (7–37) Actions on Endocrine Pancreas

1989 • 254 citations

Glucagonostatic and Insulinotropic Action of Glucagonlike Peptide I-(7–36)-Amide

1989 • 222 citations

The primary structure of porcine glicentin (proglucagon)

1981 • 206 citations

Complete Sequences of Glucagon-like Peptide-1 from Human and Pig Small Intestine

1989 • 201 citations

GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans

1989 • 176 citations

Identification and Localization of Glucagon-Like Peptide-1 and Its Receptor in Rat Brain*

1987 • 166 citations

Cellular localization of proglucagon/glucagon‐like peptide I messenger RNAs in rat brain

1986 • 165 citations

Isolation of glucagon‐37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno‐ileum

1982 • 157 citations

Receptors for glucagon-like peptide-1(7–36) amide on rat insulinoma-derived cells

1988 • 153 citations

Localization of glucagon-like peptide (GLP) immunoreactants in human gut and pancreas using light and electron microscopic immunocytochemistry.

1985 • 127 citations

Identical mRNA for preproglucagon in pancreas and gut

1987 • 121 citations

Conversion of proglucagon in pancreatic alpha cells: the major endproducts are glucagon and a single peptide, the major proglucagon fragment, that contains two glucagon-like sequences.

1984 • 117 citations

Structure of the human ghicagon gene

1986 • 113 citations

Human glucagon‐like peptides 1 and 2 activate rat brain adenylate cyclase

1984 • 111 citations

Identification and characterization of glucagon‐like peptide‐1 7–36 amide‐binding sites in the rat brain and lung

1988 • 110 citations

Comparison of the Effects of Various C-Terminal and NTerminal Fragment Peptides of Glucagon-Like Peptide-1 on Insulin and Glucagon Release from the Isolated Perfused Rat Pancreas*

1989 • 109 citations

Glucagon-Like Peptide-I Analogs: Effects on Insulin Secretion and Adenosine 3′,5′-Monophosphate Formation*

1990 • 106 citations

Characterization of glucagon-like peptide-1-(7–36)amide in the hypothalamus

1989 • 104 citations

Cell-specific post-translational processing of preproglucagon expressed from a metallothionein-glucagon fusion gene.

1986 • 100 citations

Comparison of the Effects of Glucagon-Like Peptide-1-( 1-3 7) and -(7-37) and Glucagon on Islet Hormone Release from Isolated Perfused Canine and Rat Pancreases*

1989 • 85 citations

Effect of glucagon-like peptide-1 on insulin secretion

1988 • 70 citations

Colchicine-induced redistribution of an apical membrane glycoprotein (gp330) in proximal tubules

1989 • 69 citations

Characterization of high‐affinity receptors for truncated glucagon‐like peptide‐1 in rat gastric glands

1990 • 67 citations

Glucagon‐like peptides activate hepatic gluconeogenesis

1987 • 67 citations

Mutations in the guinea pig preproglucagon gene are restricted to a specific portion of the prohormone sequence

1986 • 65 citations

Effects of Glucagonlike Peptide l-(7–36) on Release of Insulin, Glucagon, and Somatostatin by Rat Pancreatic Islet Cell Monolayer Cultures

1989 • 65 citations

Molecular forms of glucagon‐like peptides in man

1985 • 64 citations

Immunohistochemical localization of glucagon-like peptide 1

1987 • 59 citations

Response of plasma and tissue levels of enteroglucagon immunoreactivity to intestinal resection, lactation and hyperphagia

1981 • 59 citations

Synergistic stimulatory effect of glucagon‐like peptide‐1 (7–36) amide and glucose‐dependent insulin‐releasing polypeptide on the endocrine rat pancreas

1989 • 58 citations

Purification and chemical characterization of a glicentin-related pancreatic peptide (proglucagon fragment) from porcine pancreas

1982 • 56 citations

Peptides as Regulators of Gastric Acid Secretion

1988 • 56 citations

Pancreatic Somatostatin is a Mediator of Glucagon Inhibition by Hyperglycemia

1987 • 56 citations

Signal transmission after GLP-1(7-36)amide binding in RINm5F cells

1989 • 56 citations

Effect of Glucagon-Like Peptide-1 on Gastric Somatostatin and Gastrin Secretion in the Rat

1990 • 55 citations

Isolation and characterisation of GLP‐1 7–36 amide from rat intestine Elevated levels in diabetic rats

1988 • 52 citations

Characterization of the receptor for glucagon-like peptide-1(7–36)amide on plasma membranes from rat insulinoma-derived cells by covalent cross-linking

1989 • 52 citations

Molecular Forms of Glucagon-Like Peptide-1 in Human Pancreas and Glucagonomas

1985 • 51 citations

Metabolic actions of glucagon-family hormones in liver

1989 • 45 citations

Glucagon and the Glucagon-like Peptides

1990 • 45 citations

On insulin secretion

1981 • 44 citations

Effect of truncated glucagon‐like peptide 1 on cAMP in rat gastric glands and HGT‐1 human gastric cancer cells

1988 • 43 citations

Characterization of receptors for glucagon‐like peptide‐1(7–36) amide on rat lung membranes

1990 • 43 citations

How glucagon-like is glucagon-like peptide-1?

1984 • 41 citations

Priming effect of glucagon-like peptide-1 (7–36) amide, glucose-dependent insulinotropic polypeptide and cholecystokinin-8 at the isolated perfused rat pancreas

1991 • 40 citations

Glucagon-like peptide-1 does not have a role in hepatic carbohydrate metabolism

1985 • 39 citations

Proglucagon-derived peptides: nomenclature, biosynthetic relationships and physiological roles

1988 • 39 citations

Tissue-Specific Differences in the Levels of Proglucagon-Derived Peptides in Streptozotocin-Induced Diabetes*

1989 • 34 citations

Interaction of gastric inhibitory polypeptide (GIP) and cholecystokinin (CCK-8) with basal and stimulated insulin secretion in mice

1983 • 33 citations

Interaction of Glucagon-Like Peptide- 1 (7–36)amide and Somatostatin-14 in RINm5F Cells and in the Perfused Rat Pancreas

1989 • 32 citations

Interaction of Glucagon-like Peptide- 1 (7-36)amide and Cholecystokinin-8 in the Endocrine and Exocrine Rat Pancreas

1990 • 31 citations

Synergistic impact of cholecystokinin and gastric inhibitory polypeptide on the regulation of insulin secretion

1988 • 30 citations

Somatostatin analogs: Correlation of receptor affinity with inhibition of cyclic AMP formation in pancreatic acinar cells

1985 • 26 citations

Biosynthesis of regulatory peptides — evolutionary aspects

1989 • 25 citations

Effects of glucagonlike peptide I-(7-36) on release of insulin, glucagon, and somatostatin by rat pancreatic islet cell monolayer cultures

1989 • 23 citations

Release of glucagon-like peptide 1 immunoreactivity from the perfused rat pancreas

1987 • 20 citations

Identification of Glucagon-Like Peptide-1(7–36) Amide in Rat Brain

1989 • 20 citations

<b>EFFECT OF GLUCAGON-LIKE PEPTIDE-1 AND -2 ON GLYCOGENOLYSIS IN CULTURED RAT </b><b>HEPATOCYTES </b>

1986 • 18 citations

A large molecular form of glucagon-like peptide-1(GLP-1) immunoreactivity is co-released with glucagon from pancreas by arginine in normal subjects

1987 • 18 citations

[Effect of glucagon].

1961 • 16 citations

Action of glucagon and glucagon-like peptide on glycogen metabolism of trout isolated hepatocytes

1990 • 16 citations

Dexamethasone pretreatment of rat insulinoma cells decreases binding of glucagon-like peptide-1(7–36)amide

1990 • 15 citations

Isolation and chemical characterization of glicentin C‐terminal hexapeptide in porcine pancreas

1985 • 15 citations

Internalization of glucagon-like peptide-1(7–36)amide in rat insulinoma cells

1989 • 11 citations

Pancreatic peptides

1989 • 10 citations

Glucagon and related peptides (an overview).

1990 • 9 citations

<b>GLUCAGON-LIKE PEPTIDE-1 IN THE RAT </b><b>PANCREAS </b>

1987 • 8 citations

[The entero-insular axis: the new incretin candidate glucagon-like peptide-1(7-36)amide (GLP-1(7-36))amide].

1988 • 8 citations

Glucagon-like peptide-1 and the entero-insular axis in obese hyperglycaemic (ob/ob)mice

1987 • 8 citations

Effect of proglucagon-derived peptides on amylase release from rat pancreatic acini

1990 • 8 citations

Staircase potentiation in isolated frog skeletal muscle: Power spectral analysis of the evoked compound muscle action potential

1990 • 6 citations

<b>Effect of glucagon-like peptide 1 (GLP-1) antibodies on glucose-induced insulin secretion in </b><b>rats </b>

1989 • 2 citations