Role of growth factors in inflammation and repair

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

1986 • 2,499 citations

The biology of platelet-derived growth factor

1986 • 2,036 citations

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

1985 • 1,687 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Interleukin-1

1984 • 1,625 citations

Production of transforming growth factor beta by human T lymphocytes and its potential role in the regulation of T cell growth.

1986 • 1,617 citations

Transforming growth factor-beta in human platelets. Identification of a major storage site, purification, and characterization.

1983 • 1,613 citations

Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro

1985 • 1,596 citations

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

1985 • 1,594 citations

The role of the macrophage in wound repair. A study with hydrocortisone and antimacrophage serum.

1975 • 1,445 citations

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

1987 • 1,287 citations

Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.

1985 • 1,240 citations

Macrophage-induced angiogenesis is mediated by tumour necrosis factor-α

1987 • 1,210 citations

Wound Macrophages Express TGF-α and Other Growth Factors in Vivo: Analysis by mRNA Phenotyping

1988 • 1,107 citations

Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.

1984 • 1,042 citations

Expression and secretion of type beta transforming growth factor by activated human macrophages.

1987 • 981 citations

Interleukin 1, a potential regulator of fibroblast proliferation.

1982 • 835 citations

Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta.

1987 • 791 citations

POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS

1972 • 742 citations

Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-beta.

1987 • 736 citations

A significant part of macrophage-derived growth factor consists of at least two forms of PDGF

1985 • 719 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

Transforming growth factor α

1988 • 707 citations

Stimulation of tyrosine-specific phosphorylation by platelet-derived growth factor

1982 • 675 citations

Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors.

1986 • 674 citations

Distribution and modulation of the cellular receptor for transforming growth factor-beta.

1987 • 556 citations

Chemotaxis of monocytes and neutrophils to platelet-derived growth factor.

1982 • 553 citations

Gamma interferon enhances macrophage transcription of the tumor necrosis factor/cachectin, interleukin 1, and urokinase genes, which are controlled by short-lived repressors.

1986 • 532 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

Purification of the fibroblast growth factor activity from bovine brain.

1978 • 498 citations

Epidermal growth factor-like transforming growth factor. II. Interaction with epidermal growth factor receptors in human placenta membranes and A431 cells.

1983 • 484 citations

Transforming growth factor beta regulates the expression and structure of extracellular matrix chondroitin/dermatan sulfate proteoglycans.

1988 • 418 citations

Transforming growth factor-beta is a potent immunosuppressive agent that inhibits IL-1-dependent lymphocyte proliferation.

1988 • 392 citations

Activated human monocytes express the c-sis proto-oncogene and release a mediator showing PDGF-like activity

1986 • 380 citations

The c-sis gene encodes a precursor of the B chain of platelet-derived growth factor.

1984 • 376 citations

Interleukin 1 stimulation of collagenase production by cultured fibroblasts.

1983 • 373 citations

Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor

1985 • 372 citations

Platelet-derived growth factor. II. Specific binding to cultured cells.

1982 • 366 citations

Induction of transforming growth factor-α in activated human alveolar macrophages

1988 • 359 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Fibroblast growth factor: Structural and biological properties

1987 • 334 citations

Lymphokine stimulation of collagen accumulation.

1976 • 322 citations

Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.

1980 • 282 citations

Inflammation: Basic Principles and Clinical Correlates

1988 • 275 citations

The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin.

1987 • 274 citations

Human leukocytic pyrogen: purification and development of a radioimmunoassay.

1977 • 269 citations

Stimulation of in vitro human skin collagenase expression by platelet-derived growth factor.

1985 • 236 citations

Platelet-derived growth factor. Structure, function, and roles in normal and transformed cells.

1984 • 178 citations

Nucleotide sequence analysis identifies the human c-sis proto-oncogene as a structural gene for platelet-derived growth factor

1984 • 170 citations

Mononuclear Cell-Conditioned Medium Containing Mononuclear Cell Factor (MCF), Homologous With Interleukin 1, Stimulates Collagen and Fibronectin Synthesis by Adherent Rheumatoid Synovial Cells: Effects of Prostaglandin E2 and Indomethacin

1985 • 165 citations

Platelet-derived growth factor. Specific binding to target cells.

1982 • 163 citations

Reprogramming cell differentiation in the absence of DNA synthesis

1984 • 149 citations

Biosynthesis and regulation of type V collagen in diploid human fibroblasts.

1983 • 142 citations

Influences of gamma interferon on synovial fibroblast-like cells. Ia induction and inhibition of collagen synthesis.

1985 • 134 citations

Bacterial cell wall-induced hepatic granulomas. An in vivo model of T cell-dependent fibrosis.

1986 • 82 citations

Platelet-derived growth factor stimulates mouse 3T3 cell mitogenesis and leukocyte chemotaxis through different structural determinants.

1983 • 81 citations

Increased proliferation of human synovial fibroblasts treated with recombinant immune interferon.

1985 • 79 citations

Macrophage-Derived Growth Factor for Fibroblasts and Interleukin-1 Are Distinct Entities

1984 • 71 citations

Spontaneous production of fibroblast-activating factor(s) by synovial inflammatory cells. A potential mechanism for enhanced tissue destruction.

1985 • 55 citations

Synthesis of biologically active fibroblast-activating factor (FAF) by Xenopus oocytes injected with T lymphocyte mRNA

1987 • 7 citations