CD3+CD16+NK1.1+B220+ large granular lymphocytes arise from both alpha-beta TCR+CD4-CD8- and gamma-delta TCR+CD4-CD8- cells.

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Fc Receptors

1991 • 1,220 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

The T Cell Receptor/CD3 Complex: A Dynamic Protein Ensemble

1988 • 786 citations

The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways

1991 • 782 citations

Characterization of a monoclonal antibody which detects all murine alpha beta T cell receptors.

1989 • 778 citations

Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain.

1993 • 714 citations

Characterization of a murine monoclonal antibody specific for an allotypic determinant on T cell antigen receptor.

1985 • 676 citations

Alterations in Signal Transduction Molecules in T Lymphocytes from Tumor-Bearing Mice

1992 • 650 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

Two gut intraepithelial CD8+ lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation.

1991 • 599 citations

Monoclonal xenogeneic antibodies to murine cell surface antigens: identification of novel leukocyte differentiation antigens

1978 • 589 citations

B220: a B cell-specific member of the T200 glycoprotein family

1981 • 525 citations

Surface Antigen Expression and Immunoglobulin Gene Rearrangement During Mouse pre‐B Cell Development

1983 • 490 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Molecular and Cellular Events of T Cell Development

1989 • 466 citations

The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules

1992 • 438 citations

Activation of T Cells by a Tyrosine Kinase Activation Domain in the Cytoplasmic Tail of CD3 ε

1992 • 430 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritis.

1989 • 402 citations

A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family

1987 • 397 citations

The T Cell Antigen Receptor: Insights into Organelle Biology

1990 • 361 citations

Structural Heterogeneity and Functional Domains of Murine Immunoglobulin G Fc Receptors

1986 • 343 citations

Sequence requirements for induction of cytolysis by the T cell antigenFc receptor ζ chain

1992 • 333 citations

T-cell and basophil activation through the cytoplasmic tail of T-cell-receptor zeta family proteins.

1991 • 307 citations

Molecular Cloning of the Zeta Chain of the T Cell Antigen Receptor

1988 • 275 citations

Genetic and Mutational Analysis of the T-Cell Antigen Receptor

1990 • 275 citations

A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells

1992 • 264 citations

Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs.

1989 • 257 citations

Family of disulphide-linked dimers containing the ζ and η chains of the T-cell receptor and the γ chain of Fc receptors

1990 • 249 citations

Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes

1987 • 248 citations

T cell development in mice lacking the CD3-zeta/eta gene.

1993 • 235 citations

The Human T-Cell Receptor

1984 • 232 citations

Complete structure of the mouse mast cell receptor for IgE (Fc ϵ RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells

1989 • 231 citations

The Antigen-Specific, Major Histocompatibility Complex-Restricted Receptor on T Cells

1986 • 225 citations

Phenotypic, functional, and molecular genetic comparisons of the abnormal lymphoid cells of C3H-lpr/lpr and C3H-gld/gld mice.

1986 • 224 citations

The development of autoimmunity in C57BL/6 lpr mice correlates with the disappearance of natural killer type 1-positive cells: evidence for their suppressive action on bone marrow stem cell proliferation, B cell immunoglobulin secretion, and autoimmune symptoms.

1993 • 219 citations

The γδT Cell Receptor

1988 • 214 citations

High and low affinity IL 2 receptors: analysis by IL 2 dissociation rate and reactivity with monoclonal anti-receptor antibody PC61.

1985 • 203 citations

Unusual T cell populations in adult murine bone marrow. Prevalence of CD3+CD4-CD8- and alpha beta TCR+NK1.1+ cells.

1990 • 196 citations

Abnormal T cell development in CD3-zeta-/- mutant mice and identification of a novel T cell population in the intestine.

1993 • 186 citations

Functional properties of a unique subset of cytotoxic CD3+ T lymphocytes that express Fc receptors for IgG (CD16/Leu-11 antigen).

1985 • 171 citations

Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.

1990 • 169 citations

The extrathymic T-cell development pathway

1992 • 169 citations

The NK-1.1(-) mouse: a model to study differentiation of murine NK cells.

1986 • 165 citations

Mechanisms for Regulating Expression of Membrane Isoforms of FcγRIII (CD16)

1989 • 162 citations

A novel monoclonal antibody against murine IL-2 receptor beta-chain. Characterization of receptor expression in normal lymphoid cells and EL-4 cells.

1991 • 158 citations

NK1.1+ thymocytes. Adult murine CD4-, CD8- thymocytes contain an NK1.1+, CD3+, CD5hi, CD44hi, TCR-V beta 8+ subset.

1990 • 141 citations

A subunit common to an IgG Fc receptor and the T-cell receptor mediates assembly through different interactions.

1991 • 141 citations

Age-dependent increase of extrathymic T cells in the liver and their appearance in the periphery of older mice.

1992 • 130 citations

The fate of CD4-8- T cell receptor-alpha beta+ thymocytes.

1991 • 129 citations

Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.

1989 • 118 citations

Extrathymic differentiation of intraepithelial lymphocytes: generation of a separate and unequal T-cell repertoire?

1991 • 114 citations

Reconstitution of functional interleukin 2 receptor complexes on fibroblastoid cells: involvement of the cytoplasmic domain of the gamma chain in two distinct signaling pathways.

1993 • 114 citations

Phenotype, ontogeny, and repertoire of CD4-CD8- T cell receptor alpha beta + thymocytes. Variable influence of self-antigens on T cell receptor V beta usage.

1991 • 107 citations

cAMP antagonizes interleukin 2-promoted T-cell cycle progression at a discrete point in early G1.

1988 • 97 citations

Molecular cloning of the CD3 eta subunit identifies a CD3 zeta-related product in thymus-derived cells.

1990 • 92 citations

Isolation and characterization of a cDNA clone encoding the murine homologue of the human 20K T3/T-cell receptor glycoprotein

1985 • 86 citations

Role of associated gamma-chain in tyrosine kinase activation via murine Fc gamma RIII.

1992 • 83 citations

Studies of CD4- CD8- alpha beta bone marrow T cells with suppressor activity.

1992 • 82 citations

Biochemical Characterization of the η Chain of the T-cell Receptor

1989 • 80 citations

Structural similarity between Fc receptors and T cell receptors. Expression of the gamma-subunit of Fc epsilon RI in human T cells, natural killer cells and thymocytes.

1991 • 76 citations

The Isolation and Characterization of the Murine T Cell Antigen Receptor ζ Chain Gene

1989 • 76 citations

T cell receptor complexes containing Fc epsilon RI gamma homodimers in lieu of CD3 zeta and CD3 eta components: a novel isoform expressed on large granular lymphocytes.

1992 • 72 citations

Developmental potential of CD4-8- thymocytes. Peripheral progeny include mature CD4-8- T cells bearing alpha beta T cell receptor.

1989 • 71 citations

Activation of peripheral blood T cells via the p75 interleukin 2 receptor.

1989 • 70 citations

T‐Cell Lineages, Repertoire Selection and Tolerance Induction

1988 • 67 citations

T cell lineages in the thymus of lpr/lpr mice. Evidence for parallel pathways of normal and abnormal T cell development.

1987 • 66 citations

Evidence for extrathymic development of TNK cells. NK1+ CD3+ cells responsible for acute marrow graft rejection are present in thymus-deficient mice.

1992 • 64 citations

Gene mapping of the three subunits of the high affinity FcR for IgE to mouse chromosomes 1 and 19.

1989 • 63 citations

Exon/intron organization of the genes coding for the delta chains of the human and murine T-cell receptor/T3 complex.

1986 • 56 citations

T cell antigen receptor expression by subsets of Ly-2-L3T4- (CD8-CD4-) thymocytes.

1988 • 51 citations

Signal transduction by the cytoplasmic domains of Fc epsilon RI-gamma and TCR-zeta in rat basophilic leukemia cells.

1992 • 50 citations

The high affinity Fc epsilon receptor gamma subunit (Fc epsilon RI gamma) facilitates T cell receptor expression and antigen/major histocompatibility complex-driven signaling in the absence of CD3 zeta and CD3 eta

1991 • 50 citations

Intrathymic differentiation of V gamma 3 T cells.

1993 • 48 citations

Definition of a population of CD4-8- T cells that express the alpha beta T-cell receptor and respond to interleukins 2, 3, and 4.

1989 • 47 citations

Distinctive selection mechanisms govern the T cell receptor repertoire of peripheral CD4-CD8- alpha/beta T cells.

1992 • 43 citations

The Expression of CD4 and CD8 Accessory Molecules on Mature T Cells is not Random but Correlates with the Specificity of the αβ Receptor for Antigen

1989 • 42 citations

CD3 zeta subunit can substitute for the gamma subunit of Fc epsilon receptor type I in assembly and functional expression of the high-affinity IgE receptor: evidence for interreceptor complementation.

1990 • 42 citations

Tolerance of T cell receptor gamma/delta cells in the intestine.

1993 • 36 citations

CD3+4-8- alpha beta T cell population with biased T cell receptor V gene usage. Presence in bone marrow and possible involvement of IL-3 for their extrathymic development.

1992 • 34 citations

Molecular and Functional Properties of Novel T Cell Subsets in C3H‐gld/gld and Nude Mice. Implications for Thymic and Extrathymic Maturation

1988 • 33 citations

CD4-CD8- T cell receptor alpha beta T cells: generation of an in vitro major histocompatibility complex class I specific cytotoxic T lymphocyte response and allogeneic tumor rejection.

1991 • 33 citations

Developmental Biology Of T Cells In T Cell-Receptor Transgenic Mice

1990 • 28 citations

Murine epidermal γ/δ T cells express Fcγ receptor II encoded by the FcγRα α gene

1991 • 22 citations

Role of T-cell antigens in the cytolytic activities of large granular lymphocytes (LGLs) in patients with LGL lymphocytosis

1988 • 21 citations

Expression and role of interleukin‐2 receptor β chain on CD4⁻CD8⁺ T cell receptor αβ⁺ cells

1992 • 16 citations

Generation of natural killer cells from both Fc gamma RII/III+ and Fc gamma RII/III- murine fetal liver progenitors

1993 • 15 citations

Genetic And Mutational Analysis Of The T-Cell Antigen Receptor

1990 • 13 citations

The expression of IL-2R alpha-chain is enhanced by activation of adenylate cyclase in large granular lymphocytes and natural killer cells.

1991 • 11 citations

The role of the interleukin‐2 (IL‐2)/IL‐2 receptor pathway in MRL/lpr lymphadenopathy: The expanded CD4⁻8⁻ T cell subset completely lacks functional IL‐2 receptors

1993 • 11 citations

Overexpression of CD3 eta during thymic development does not alter the negative selection process.

1993 • 8 citations

High-molecular-weight Ly-5 isoforms expressed on T cells: activation-dependent expression

1991 • 7 citations

T-cell-receptor isoforms.

1992 • 4 citations

Role of T-cell antigens in the cytolytic activities of large granular lymphocytes (LGLs) in patients with LGL lymphocytosis

1988 • 3 citations