Carbachol Stimulates Transactivation of Epidermal Growth Factor Receptor and Mitogen-activated Protein Kinase in T84Cells

PD 098059 Is a Specific Inhibitor of the Activation of Mitogen-activated Protein Kinase Kinase in Vitro and in Vivo

1995 • 3,456 citations

The MAPK signaling cascade

1995 • 3,300 citations

A synthetic inhibitor of the mitogen-activated protein kinase cascade.

1995 • 2,723 citations

Tyrosine Kinase Inhibition: An Approach to Drug Development

1995 • 1,655 citations

Protein tyrosine kinase PYK2 involved in Ca2+-induced regulation of ion channel and MAP kinase functions

1995 • 1,367 citations

A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

1996 • 971 citations

Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors

1997 • 454 citations

Mitogenic Signaling via G Protein-Coupled Receptors

1996 • 425 citations

Hepatobiliary complications of total parenteral nutrition

1993 • 354 citations

Regulation of the ERK Subgroup of MAP Kinase Cascades Through G Protein-Coupled Receptors

1997 • 323 citations

Mechanism of chloride secretion induced by carbachol in a colonic epithelial cell line.

1986 • 321 citations

Ba2+ inhibition of VIP- and A23187-stimulated Cl- secretion by T84 cell monolayers

1986 • 246 citations

Protein Kinase C-ζ Mediates Angiotensin II Activation of ERK1/2 in Vascular Smooth Muscle Cells

1997 • 220 citations

The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity

1997 • 213 citations

Protein Kinase C, but Not Tyrosine Kinases or Ras, Plays a Critical Role in Angiotensin II-induced Activation of Raf-1 Kinase and Extracellular Signal-regulated Protein Kinases in Cardiac Myocytes

1996 • 211 citations

cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor genistein

1995 • 207 citations

Stimulation of growth factor receptor signal transduction by activation of voltage-sensitive calcium channels.

1996 • 174 citations

Modulation of CFTR chloride channels by calyculin A and genistein

1997 • 149 citations

Alternate stimulation of apical CFTR by genistein in epithelia

1996 • 146 citations

Chloride secretory mechanism induced by prostaglandin E1 in a colonic epithelial cell line.

1985 • 146 citations

Angiotensin II Controls p21 Activity via pp60

1996 • 138 citations

Epidermal growth factor inhibits Ca(2+)-dependent Cl- transport in T84 human colonic epithelial cells

1996 • 127 citations

Characterization of a cyclic AMP-activated Cl-transport pathway in the apical membrane of a human colonic epithelial cell line.

1986 • 126 citations

Phosphatidylinositol 3-Kinase Mediates the Inhibitory Effect of Epidermal Growth Factor on Calcium-dependent Chloride Secretion

1996 • 118 citations

Secondary Dimerization between Members of the Epidermal Growth Factor Receptor Family

1997 • 101 citations

Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells

1997 • 84 citations

CFTR chloride channel activation by genistein: the role of serine/threonine protein phosphatases

1996 • 69 citations

Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.

1995 • 62 citations

Cholinergic activation of Cl− secretion in rat colonic epithelia

1995 • 60 citations

Bowditch lecture. Integrated regulation of intestinal epithelial transport: intercellular and intracellular pathways

1997 • 56 citations

Activation of T84 cell chloride channels by carbachol involves a phosphoinositide-coupled muscarinic M3 receptor

1992 • 55 citations

Stimulated Mitogen-activated Protein Kinase Is Necessary but Not Sufficient for the Mitogenic Response to Angiotensin II

1996 • 51 citations

Stimulation of tyrosine phosphorylation and mitogen-activated-protein (MAP) kinase activity in human SH-SY5Y neuroblastoma cells by carbachol

1993 • 42 citations

Role for tyrosine kinases in carbachol-regulated Ca entry into colonic epithelial cells

1995 • 30 citations

Regulation of Mitogen-Activated Protein Kinase Pathways by Catecholamine Receptors

1997 • 5 citations