Acute Ketamine Administration Alters the Brain Responses to Executive Demands in a Verbal Working Memory Task: an fMRI Study

Statistical parametric maps in functional imaging: A general linear approach

1994 • 9,606 citations

Thresholding of Statistical Maps in Functional Neuroimaging Using the False Discovery Rate

2002 • 4,885 citations

Subanesthetic Effects of the Noncompetitive NMDA Antagonist, Ketamine, in Humans

1994 • 3,182 citations

Recent advances in the phencyclidine model of schizophrenia

1991 • 2,886 citations

Temporal dynamics of brain activation during a working memory task

1997 • 1,879 citations

Nonlinear spatial normalization using basis functions

1999 • 1,860 citations

Activation of Glutamatergic Neurotransmission by Ketamine: A Novel Step in the Pathway from NMDA Receptor Blockade to Dopaminergic and Cognitive Disruptions Associated with the Prefrontal Cortex

1997 • 1,743 citations

Glutamate Receptor Dysfunction and Schizophrenia

1995 • 1,682 citations

A Parametric Study of Prefrontal Cortex Involvement in Human Working Memory

1997 • 1,643 citations

Frontal lobes and human memory: Insights from functional neuroimaging

2001 • 1,344 citations

The Neuropsychopharmacology of Phencyclidine From NMDA Receptor Hypofunction to the Dopamine Hypothesis of Schizophrenia

1999 • 1,300 citations

The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive

1996 • 1,053 citations

Dissociating Verbal and Spatial Working Memory Using PET

1996 • 961 citations

Schizophrenics Show Spatial Working Memory Deficits

1992 • 953 citations

Subanesthetic Doses of Ketamine Stimulate Psychosis in Schizophrenia

1995 • 891 citations

Maintenance versus Manipulation of Information Held in Working Memory: An Event-Related fMRI Study

1999 • 782 citations

Physiological Characteristics of Capacity Constraints in Working Memory as Revealed by Functional MRI

1999 • 770 citations

Verbal Working Memory Load Affects Regional Brain Activation as Measured by PET

1997 • 696 citations

Developments in the concept of working memory.

1994 • 660 citations

Glutamatergic Mechanisms in Schizophrenia

2002 • 579 citations

Methodology Of Frontal And Executive Function

2004 • 534 citations

Schizophrenic subjects show aberrant fMRI activation of dorsolateral prefrontal cortex and basal ganglia during working memory performance

2000 • 498 citations

Frontal-striatal cognitive deficits in patients with chronic schizophrenia

1997 • 434 citations

Effects of ketamine on sensory perception: evidence for a role of N-methyl-D-aspartate receptors.

1992 • 412 citations

Functional Hypofrontality and Working Memory Dysfunction in Schizophrenia

1998 • 403 citations

Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers

1997 • 393 citations

Schizophrenic subjects activate dorsolateral prefrontal cortex during a working memory task, as measured by fMRI

1999 • 390 citations

Differential psychopathology and patterns of cerebral glucose utilisation produced by (S)- and (R)-ketamine in healthy volunteers using positron emission tomography (PET)

1997 • 388 citations

Schizophrenia and Glutamatergic Transmission

1998 • 385 citations

Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia

2000 • 374 citations

Cognitive Deficits in Schizophrenia

1993 • 371 citations

Theory and Methodology in Executive Function Research

2004 • 349 citations

Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG)

1997 • 349 citations

Neurobiology of Mental Illness.

2000 • 344 citations

Functional neuroanatomical double dissociation of mnemonic and executive control processes contributing to working memory performance

1999 • 344 citations

Functional Magnetic Resonance Imaging Brain Mapping in Psychiatry: Methodological Issues Illustrated in a Study of Working Memory in Schizophrenia

1998 • 325 citations

Coactivation of prefrontal cortex and inferior parietal cortex in working memory tasks revealed by 2DG functional mapping in the rhesus monkey

1994 • 313 citations

Effects of Ketamine on Thought Disorder, Working Memory, and Semantic Memory in Healthy Volunteers

1998 • 305 citations

Verbal Working Memory Impairment in Schizophrenia Patients and Their First-Degree Relatives: Evidence From the Digit Span Task

2000 • 279 citations

Attenuated Frontal Activation During a Verbal Fluency Task in Patients With Schizophrenia

1998 • 250 citations

Visual Perceptual and Working Memory Impairments in Schizophrenia

2002 • 208 citations

Glutamate Modulation of Dopamine Measured in Vivo with Positron Emission Tomography (PET) and 11C-Raclopride in Normal Human Subjects

1998 • 199 citations

Frontal/Executive Impairments in Schizophrenia

1996 • 197 citations

Ketamine

1985 • 193 citations

Functional Neuroanatomy of Auditory Working Memory in Schizophrenia: Relation to Positive and Negative Symptoms

2001 • 161 citations

A glutamatergic deficiency model of schizophrenia

1999 • 155 citations

Sequential Regional Cerebral Blood Flow Brain Scans Using PET with H215O Demonstrate Ketamine Actions in CNS Dynamically

2001 • 152 citations

Plasma levels of ketamine and two of its metabolites in surgical patients using a gas chromatographic mass fragmentographic assay.

1982 • 150 citations

Executive-frontal lobe cognitive dysfunction in schizophrenia: A symptom subtype analysis

1998 • 145 citations

Plasma Levels of Ketamine and Two of Its Metabolites in Surgical Patients Using a Gas Chromatographic Mass Fragmentographic Assay

1982 • 139 citations

Metabolism of Ketamine Stereoisomers by Human Liver Microsomes

1992 • 131 citations

Glutamatergic aspects of schizophrenia

1999 • 116 citations

A Pivotal Role for Glutamate in the Pathogenesis of Schizophrenia, and Its Cognitive Dysfunction

1997 • 105 citations

Pharmacokinetic concepts for TCI anaesthesia

1998 • 90 citations

Subdissociative Dose Ketamine Produces a Deficit in Manipulation but not Maintenance of the Contents of Working Memory

2003 • 74 citations

Spatial working memory performance in patients with schizoaffective psychosis versus schizophrenia: a tale of two disorders?

2002 • 69 citations

Prefrontal Cortex Involvement in Selective Letter Generation: A Functional Magnetic Resonance Imaging Study

1998 • 42 citations

Neurochemical alterations in schizophrenia affecting the putative receptor targets of atypical antipsychotics

1999 • 37 citations

Deficit of central executive component of working memory in schizophrenia

1996 • 19 citations