Phosphorylation Specificities of Protein Kinase C Isozymes for Bovine Cardiac Troponin I and Troponin T and Sites within These Proteins and Regulation of Myofilament Properties

Protein kinase C and lipid signaling for sustained cellular responses

1995 • 2,527 citations

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976

1993 • 1,589 citations

[18] Purification of muscle actin

1982 • 1,186 citations

Protein kinase C - a question of specificity

1994 • 958 citations

Structural Changes in the Actin- and Myosin-eontaining Filaments during Contraction

1973 • 544 citations

Structural Aspects of Troponin-Tropomyosin Regulation of Skeletal Muscle Contraction

1987 • 529 citations

Structural role of tropomyosin in muscle regulation: Analysis of the X-ray diffraction patterns from relaxed and contracting muscles

1973 • 491 citations

X-Ray Evidence for a Conformational Change in the Actin-containing Filaments of Vertebrate Striated Muscle

1973 • 391 citations

Inhibition of actomyosin ATPase activity by troponin-tropomyosin without blocking the binding of myosin to actin.

1982 • 349 citations

Localization of Protein Kinase C Isozymes in Cardiac Myocytes

1994 • 342 citations

Differential regulation of protein kinase C isoforms in isolated neonatal and adult rat cardiomyocytes

1994 • 280 citations

[21] Preparation and identification of α- and β-tropomyosins

1982 • 259 citations

Characterization of protein kinase C isotype expression in adult rat heart. Protein kinase C-epsilon is a major isotype present, and it is activated by phorbol esters, epinephrine, and endothelin.

1993 • 252 citations

Protein kinase C isoform expression and regulation in the developing rat heart.

1994 • 245 citations

Cyclic nucleotide-dependent protein kinases. V. Preparation and properties of adenosine 3′,5′-monophosphate-dependent protein kinase from various bovine tissues

1970 • 189 citations

Phosphorylation of the inhibitory subunit of troponin and its effect on the calcium dependence of cardiac myofibril adenosine triphosphatase

1976 • 188 citations

Kinetics of the interaction between actin, ADP, and cardiac myosin-S1.

1984 • 187 citations

Protein kinase C-mediated phosphorylation of troponin I and C-protein in isolated myocardial cells is associated with inhibition of myofibrillar actomyosin MgATPase.

1993 • 178 citations

Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha.

1993 • 166 citations

Cardiac Troponin I Mutants

1995 • 164 citations

Phosphorylation of Both Serine Residues in Cardiac Troponin I Is Required to Decrease the Ca2+ Affinity of Cardiac Troponin C

1995 • 149 citations

Phosphorylation of cardiac troponin by cyclic adenosine 3':5'-monophosphate-dependent protein kinase.

1977 • 148 citations

Phosphorylation of cardiac troponin inhibitory subunit (troponin I) and tropomyosin-binding subunit (troponin T) by cardiac phospholipid-sensitive Ca2+-dependent protein kinase

1983 • 139 citations

Calcium-Induced Movement of Troponin-I Relative to Actin in Skeletal Muscle Thin Filaments

1990 • 131 citations

Identification of sites phosphorylated in bovine cardiac troponin I and troponin T by protein kinase C and comparative substrate activity of synthetic peptides containing the phosphorylation sites

1989 • 126 citations

The biological importance of each amino acid residue of the troponin I inhibitory sequence 104-115 in the interaction with troponin C and tropomyosin-actin.

1988 • 113 citations

Protein kinase C phosphorylation of cardiac troponin I or troponin T inhibits Ca2(+)-stimulated actomyosin MgATPase activity.

1991 • 106 citations

The Unique Amino-terminal Peptide of Cardiac Troponin I Regulates Myofibrillar Activity Only When it is Phosphorylated

1995 • 102 citations

Role of protein kinase C in the phosphorylation of cardiac myosin light chain 2

1993 • 94 citations

Calcium binding to the low affinity sites in troponin C induces conformational changes in the high affinity domain. A possible route of information transfer in activation of muscle contraction.

1986 • 80 citations

Protein Kinase C Phosphorylation of Cardiac Troponin I and Troponin T Inhibits Ca2+-Stimulated MgATPase Activity in Reconstituted Actomyosin and Isolated Myofibrils, and Decreases Actin-Myosin Interactions

1993 • 78 citations

Protein phosphorylation in heart muscle

1986 • 69 citations

Sites phosphorylated in bovine cardiac troponin T and I

1990 • 60 citations

Protein kinase C phosphorylation of cardiac troponin T decreases Ca2+-dependent actomyosin MgATPase activity and troponin T binding to tropomyosin-F-actin complex

1992 • 54 citations

NH2-terminal Truncation of Skeletal Muscle Troponin T Does Not Alter the Ca2+ Sensitivity of Thin Filament Assembly

1995 • 47 citations

The effect of troponin-tropomyosin on the binding of heavy meromyosin to actin in the presence of ATP.

1986 • 46 citations

[55] Expression of protein kinase c isotypes using baculovirus vectors

1991 • 43 citations

Equilibrium linkage analysis of cardiac thin filament assembly. Implications for the regulation of muscle contraction.

1994 • 41 citations

Calcium-insensitive binding of heavy meromyosin to regulated actin at physiological ionic strength.

1985 • 35 citations

Phorbol Ester Regulation of Opioid Peptide Gene Expression in Myocardial Cells

1995 • 32 citations