Alcohol‐responsive genes in the frontal cortex and nucleus accumbens of human alcoholics

Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.

1988 • 4,617 citations

Synaptic Vesicle Phosphoproteins and Regulation of Synaptic Function

1993 • 1,302 citations

Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia

2001 • 1,194 citations

Analysis of gene expression in single live neurons.

1992 • 944 citations

Alterations in the morphology of dendrites and dendritic spines in the nucleus accumbens and prefrontal cortex following repeated treatment with amphetamine or cocaine

1999 • 722 citations

A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2

2003 • 643 citations

Distinct Roles of Thioredoxin in the Cytoplasm and in the Nucleus

1999 • 597 citations

Cytoarchitectonic Definition of Prefrontal Areas in the Normal Human Cortex: II. Variability in Locations of Areas 9 and 46 and Relationship to the Talairach Coordinate System

1995 • 568 citations

Alcohol promotes dopamine release in the human nucleus accumbens

2003 • 563 citations

Regulation of the NF-ηB/rel transcription factor and IηB inhibitor system

1993 • 541 citations

The cerebral cortex is damaged in chronic alcoholics

1997 • 527 citations

Oxidoreductive regulation of nuclear factor kappa B. Involvement of a cellular reducing catalyst thioredoxin

1993 • 490 citations

Cloning and Expression of a Developmentally Regulated Protein That Induces Mitogenic and Neurite Outgrowth Activity

1990 • 468 citations

Alcoholism and smoking.

1990 • 419 citations

Cocaine self-administration alters the morphology of dendrites and dendritic spines in the nucleus accumbens and neocortex

2001 • 401 citations

Gene Expression in Human Alcoholism: Microarray Analysis of Frontal Cortex

2000 • 382 citations

Patterns of gene expression are altered in the frontal and motor cortices of human alcoholics

2002 • 318 citations

Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

1993 • 282 citations

Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons.

1996 • 276 citations

Relationship between alcohol and tobacco dependencies among alcoholics who smoke

2003 • 264 citations

Changes in brain gene expression shared by scrapie and Alzheimer disease.

1989 • 253 citations

Reorganization of Frontal Systems Used by Alcoholics for Spatial Working Memory: An fMRI Study

2001 • 242 citations

Brain shrinkage in chronic alcoholics: a pathological study.

1985 • 213 citations

Gene expression profile of the nucleus accumbens of human cocaine abusers: evidence for dysregulation of myelin

2004 • 185 citations

Midkine Inhibits Caspase‐Dependent Apoptosis via the Activation of Mitogen‐Activated Protein Kinase and Phosphatidylinositol 3‐Kinase in Cultured Neurons

1999 • 184 citations

Tobacco smoking: A comparison between alcohol and drug abuse inpatients

1988 • 180 citations

Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays.

2000 • 172 citations

Ethanol elevates accumbal dopamine levels via indirect activation of ventral tegmental nicotinic acetylcholine receptors

2003 • 171 citations

The Roles of Thioredoxin in Protection against Oxidative Stress-induced Apoptosis in SH-SY5Y Cells

2002 • 165 citations

Chronic alcoholism and the frontal lobe: which executive functions are imparied?

2002 • 162 citations

The DRD4 VNTR polymorphism moderates craving after alcohol consumption.

2002 • 162 citations

Alcohol‐responsive genes in the frontal cortex and nucleus accumbens of human alcoholics

2005 • 148 citations

Neuronal counts from four cortical regions of alcoholic brains

1989 • 146 citations

Ethanol Consumption and Liver Mitochondria Function

2001 • 120 citations

Complex Formation by the Human Rad51B and Rad51C DNA Repair Proteins and Their Activities in Vitro

2003 • 118 citations

Transcription profiling reveals mitochondrial, ubiquitin and signaling systems abnormalities in postmortem brains from subjects with a history of alcohol abuse or dependence

2003 • 108 citations

α6β1 integrin directs migration of neuronal precursors in adult mouse forebrain

2003 • 103 citations

Ethanol Drinking and Deprivation Alter Dopaminergic and Serotonergic Function in the Nucleus Accumbens of Alcohol-Preferring Rats

2004 • 102 citations

Effects of Raclopride in the Nucleus Accumbens on Ethanol Seeking and Consumption

2001 • 101 citations

ADIP, a Novel Afadin- and α-Actinin-Binding Protein Localized at Cell-Cell Adherens Junctions

2003 • 100 citations

Midkine that promotes survival of fetal human neurons is produced by fetal human astrocytes in culture

1993 • 96 citations

Midkine is present in the early stage of cerebral infarct

1995 • 95 citations

Mammalian Homologue of the Caenorhabditis elegans UNC-76 Protein Involved in Axonal Outgrowth Is a Protein Kinase C ζ–interacting Protein

1999 • 90 citations

Tissue inhibitor of metalloproteinases‐3 and matrix metalloproteinase‐3 regulate neuronal sensitivity to doxorubicin‐induced apoptosis

2003 • 88 citations

Deposition of apolipoproteins E and J in senile plaques is topographically determined in both Alzheimer's disease and Down's syndrome brain

1995 • 75 citations

Differential adaptive properties of accumbens shell dopamine responses to ethanol as a drug and as a motivational stimulus

2003 • 62 citations

A mechanism for ethanol-induced damage to liver mitochondrial structure and function

1980 • 61 citations

Allelic association between D2 but not D1 dopamine receptor gene and alcoholism in Finland

1997 • 58 citations

Merlin Links to the cAMP Neuronal Signaling Pathway by Anchoring the RIβ Subunit of Protein Kinase A

2003 • 50 citations

Coregulation of Ethanol Discrimination by the Nucleus Accumbens and Amygdala

2003 • 50 citations

Structure of the human brain: A photographic atlas, 3rd ed.

1989 • 47 citations

Apoptosis and gene expression: Perspectives on alcohol-induced brain damage

1994 • 45 citations

Genotype effects on neurodegeneration and neuroadaptation in monoaminergic neurotransmitter systems

2000 • 41 citations

Testican-1 inhibits attachment of Neuro-2a cells

2003 • 38 citations

Evidence for the importance of the human dopamine transporter gene for withdrawal symptomatology of alcoholics in a German population

2002 • 37 citations

A Novel cAMP-Dependent Pathway Activates Neuronal Integrin Function in Retinal Neurons

2004 • 35 citations

Ethanol Can Modify the Effects of Certain Free Radical‐Generating Systems on Astrocytes

2004 • 35 citations

Comparative Effects of Chronic Ethanol Consumption on the Properties of Mitochondria from Rat Brain and Liver

1992 • 32 citations

Differential modulation of apoptosis-associated proteins by ethanol in rat cerebral cortex and cerebellum

2003 • 31 citations

Differential Regulation of Astrocytic mRNAs in the Rat Striatum after Lesions of the Cortex or Substantia Nigra

1998 • 28 citations

Defense mechanism to oxidative DNA damage in glial cells

2004 • 23 citations

Alteration of midkine expression in the ischemic brain of humans

2002 • 23 citations

Mitochondrial changes in rat Purkinje cells after prolonged alcohol consumption. A morphologic assessment.

1983 • 20 citations

Morphological alterations due to long term alcohol intake in rats

1987 • 13 citations