The Roles of Thioredoxin in Protection against Oxidative Stress-induced Apoptosis in SH-SY5Y Cells

The Bcl-2 Protein Family: Arbiters of Cell Survival

1998 • 5,359 citations

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

1997 • 4,921 citations

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

1993 • 3,465 citations

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

2000 • 3,415 citations

Physiological functions of thioredoxin and thioredoxin reductase

2000 • 2,440 citations

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

1998 • 2,360 citations

Induction of Apoptosis by ASK1, a Mammalian MAPKKK That Activates SAPK/JNK and p38 Signaling Pathways

1997 • 2,284 citations

THIOREDOXIN

1985 • 1,885 citations

Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro

1990 • 1,592 citations

Chemistry and Biochemistry of Flavoenzymes

2018 • 1,241 citations

REDOX REGULATION OF CELLULAR ACTIVATION

1997 • 1,121 citations

More than one way to die: apoptosis, necrosis and reactive oxygen damage

1999 • 850 citations

Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism

1984 • 772 citations

Reactive oxygen species and programmed cell death

1996 • 745 citations

Evidence that 4-Hydroxynonenal Mediates Oxidative Stress-Induced Neuronal Apoptosis

1997 • 727 citations

Mammalian Peroxiredoxin Isoforms Can Reduce Hydrogen Peroxide Generated in Response to Growth Factors and Tumor Necrosis Factor-α

1998 • 672 citations

Reactive Oxygen-Mediated Protein Oxidation in Aging and Disease

1997 • 605 citations

Lipid peroxidation, antioxidant protection and aging

1997 • 402 citations

Thioredoxin Peroxidase Is a Novel Inhibitor of Apoptosis with a Mechanism Distinct from That of Bcl-2

1997 • 372 citations

Apoptosis in Neural Development and Disease

2000 • 332 citations

Distinct effects of glutathione disulphide on the nuclear transcription factors κB and the activator protein‐1

1994 • 274 citations

Cytochrome c release and caspase activation in hydrogen peroxide‐ and tributyltin‐induced apoptosis

1998 • 254 citations

Intracranial microdialysis of salicylic acid to detect hydroxyl radical generation through dopamine autooxidation in the caudate nucleus: Effects of MPP+

1992 • 234 citations

The effect of H2O2 upon thioredoxin-enriched lens epithelial cells.

1988 • 214 citations

1-Chloro-2,4-dinitrobenzene Is an Irreversible Inhibitor of Human Thioredoxin Reductase

1995 • 185 citations

Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism.

1993 • 177 citations

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells.

1996 • 161 citations

Elevation of Manganese Superoxide Dismutase Gene Expression by Thioredoxin

1997 • 143 citations

Inhibition of Capillary Morphogenesis and Associated Apoptosis by Dominant Negative Mutant Transforming Growth Factor-β Receptors

1995 • 142 citations

Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells

1996 • 102 citations

Purification of human thioredoxin reductase: Properties and characterization by absorption and circular dichroism spectroscopy

1993 • 96 citations

Transcriptional Activation of the Human Manganese Superoxide Dismutase Gene Mediated by Tetradecanoylphorbol Acetate

1999 • 91 citations

MPP+ induced apoptotic cell death in SH-SY5Y neuroblastoma cells: An electron microscope study

1997 • 82 citations

Preconditioning regulation of bcl‐2 and p66^shc by human NOS1 enhances tolerance to oxidative stress

2000 • 81 citations

Thioredoxin increases the proliferation of human B-cell lines through a protein kinase C-dependent mechanism.

1994 • 77 citations

4‐Hydroxynonenal Induces Oxidative Stress and Death of Cultured Spinal Cord Neurons

2000 • 65 citations

Methionine sulfoxide reductase in antioxidant defense

1999 • 58 citations

Redox Modulation of AP-2 DNA Binding Activityin Vitro

1998 • 58 citations

Effects of Atypical Antioxidative Agents, S‐nitrosoglutathione and Manganese, on Brain Lipid Peroxidation Induced by Iron Leaking from Tissue Disruption

2000 • 33 citations

A Redox-Inactive Thioredoxin Reduces Growth and Enhances Apoptosis in WEHI7.2 Cells

2000 • 32 citations

Cell death by 1-chloro-2,4-dinitrobenzene, an inhibitor of thioredoxin reductase and its dual regulation by nitric oxide in rats

1999 • 25 citations