Mechanisms of the cytopathic action of actin‐ADP‐ribosylating toxins

Atomic structure of the actin: DNase I complex

1990 • 1,897 citations

Atomic model of the actin filament

1990 • 1,657 citations

ACTIN AND ACTIN-BINDING PROTEINS. A CRITICAL EVALUATION OF MECHANISMS AND FUNCTIONS

1986 • 1,493 citations

Actin polymerization and its regulation by proteins from nonmuscle cells.

1982 • 739 citations

Modulation of gelsolin function by phosphatidylinositol 4,5-bisphosphate

1987 • 624 citations

The Complete Amino Acid Sequence of Actins from Bovine Aorta, Bovine Heart, Bovine Fast Skeletal Muscle, and Rabbit, Slow Skeletal Muscle

1979 • 534 citations

Botulinum C2 toxin ADP-ribosylates actin

1986 • 503 citations

Actin-specific ADP-ribosyltransferase produced by a Clostridium difficile strain

1988 • 324 citations

Purification and characterization of two components of botulinum C2 toxin

1980 • 210 citations

Interactions of gelsolin and gelsolin-actin complexes with actin. Effects of calcium on actin nucleation, filament severing, and end blocking

1985 • 208 citations

Expression of human plasma gelsolin in Escherichia coli and dissection of actin binding sites by segmental deletion mutagenesis.

1989 • 195 citations

ADP-ribosylated actin caps the barbed ends of actin filaments.

1988 • 174 citations

Botulinum C2 toxin ADP-ribosylates cytoplasmic beta/gamma-actin in arginine 177.

1988 • 161 citations

Clostridium spiroforme toxin is a binary toxin which ADP-ribosylates cellular actin

1988 • 153 citations

ADP-ribosylation of actin by clostridial toxins.

1989 • 133 citations

ADP‐ribosylation of skeletal muscle and non‐muscle actin by Clostridium perfringens iota toxin

1988 • 125 citations

Botulinum C2 toxin ADP-ribosylates actin and disorganizes the microfilament network in intact cells.

1987 • 109 citations

Molecular basis for the pathological actions of Clostridium perfringens iota toxin

1987 • 101 citations

Response of mouse intestinal loop to botulinum C2 toxin: enterotoxic activity induced by cooperation of nonlinked protein components

1983 • 90 citations

Cellular and molecular actions of binary toxins possessing ADP-ribosyltransferase activity

1991 • 78 citations

Plasma gelsolin caps and severs actin filaments

1984 • 73 citations

ADP‐ribosylation of actin isoforms by Clostridium botulinum C2 toxin and Clostridium perfringens iota toxin

1990 • 72 citations

Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro.

1991 • 70 citations

Rate of treadmilling of actin filaments in vitro

1986 • 68 citations

Production by Clostridium spiroforme of an iotalike toxin that possesses mono(ADP-ribosyl)transferase activity: identification of a novel class of ADP-ribosyltransferases

1989 • 67 citations

The binary toxin produced by Clostridium botulinum enters cells by receptor-mediated endocytosis to exert its pharmacologic effects.

1989 • 63 citations

A comparison of the pharmacological properties of Clostridium botulinum type C1 and C2 toxins.

1982 • 62 citations

Lethal and vascular permeability activities of botulinum C2 toxin induced by separate injections of the two toxin components

1983 • 61 citations

ADP‐ribosylation of actin causes increase in the rate of ATP exchange and inhibition of ATP hydrolysis

1989 • 56 citations

Mono‐ADP‐Ribosylation in Brain: Purification and Characterization of ADP‐Ribosyltransferases Affecting Actin from Rat Brain

1991 • 50 citations

ADP-ribosylation of gelsolin-actin complexes by clostridial toxins.

1992 • 42 citations

Botulinum C2 toxin treatment increases the G-actin pool in intact chicken cells: A model for the cytopathic action of actin-ADP-ribosylating toxins

1989 • 24 citations