Insertion/Deletion Polymorphism of the Angiotensin I-Converting Enzyme Gene Is Associated With Coronary Artery Plaque Calcification As Assessed by Intravascular Ultrasound

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

1990 • 3,809 citations

Coronary Plaque Disruption

1995 • 3,542 citations

Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

1992 • 1,956 citations

Coronary Artery Calcification: Pathophysiology, Epidemiology, Imaging Methods, and Clinical Implications

1996 • 1,066 citations

A Prospective Evaluation of an Angiotensin-Converting–Enzyme Gene Polymorphism and the Risk of Ischemic Heart Disease

1995 • 920 citations

Angiotensin-Converting Enzyme in the Human Heart

1995 • 767 citations

Angiotensin II induces smooth muscle cell proliferation in the normal and injured rat arterial wall.

1991 • 751 citations

Osteopontin is elevated during neointima formation in rat arteries and is a novel component of human atherosclerotic plaques.

1993 • 642 citations

Patterns of Calcification in Coronary Artery Disease

1995 • 601 citations

Mistyping ACE heterozygotes.

1993 • 522 citations

Prognostic value of coronary calcification and angiographic stenoses in patients undergoing coronary angiography

1996 • 443 citations

Sudden Coronary Death

1995 • 407 citations

Intracoronary ultrasound imaging: Correlation of plaque morphology with angiography, clinical syndrome and procedural results in patients undergoing coronary angioplasty

1993 • 366 citations

Diffuse calcification in human coronary arteries. Association of osteopontin with atherosclerosis.

1994 • 357 citations

Noninvasive definition of anatomic coronary artery disease by ultrafast computed tomographic scanning: A quantitative pathologic comparison study

1992 • 313 citations

Deletion polymorphism of the angiotensin I-converting enzyme gene is associated with serum ACE concentration and increased risk for CAD in the Japanese.

1994 • 276 citations

Expression of osteopontin messenger RNA by macrophages in atherosclerotic plaques. A possible association with calcification.

1993 • 259 citations

Pathology of atheromatous lesions in inbred and genetically engineered mice. Genetic determination of arterial calcification.

1994 • 244 citations

Insertion/deletion polymorphism of the angiotensin-converting enzyme gene is strongly associated with coronary heart disease in non-insulin-dependent diabetes mellitus.

1994 • 236 citations

Angiotensin-Converting Enzyme Gene Polymorphism Is Associated With Myocardial Infarction but Not With Development of Coronary Stenosis

1995 • 180 citations

Limitations of Angiography in the Assessment of Plaque Distribution in Coronary Artery Disease

1996 • 179 citations

A DNA Variant at the Angiotensin-Converting Enzyme Gene Locus Associates With Coronary Artery Disease in the Caerphilly Heart Study

1995 • 179 citations

Detection of intralesional calcium by intracoronary ultrasound depends on the histologic pattern

1994 • 144 citations

Angiotensin-Converting Enzyme Gene Polymorphism Is Associated With Carotid Arterial Wall Thickness in Non–Insulin-Dependent Diabetic Patients

1996 • 99 citations

Risk factor correlates of coronary calcium as evaluated by ultrafast computed tomography

1992 • 89 citations

Angiotensin-Converting Enzyme Gene Polymorphism

1996 • 81 citations

Value and limitations of intravascular ultrasound imaging in characterizing coronary atherosclerotic plaque

1995 • 80 citations

A deletion polymorphism in the angiotensin converting enzyme gene is not associated with coronary heart disease in an Austrian population

1995 • 74 citations

Genotype Distribution of Angiotensin-Converting Enzyme Polymorphism in Australian Healthy and Coronary Populations and Relevance to Myocardial Infarction and Coronary Artery Disease

1996 • 47 citations

Intracoronary Ultrasound Imaging

1997 • 29 citations

Aortic atherosclerosis in diabetes mellitus is associated with an insertion/deletion polymorphism in the angiotensin I-converting enzyme gene

1996 • 15 citations

Analysis of the deletion/insertion polymorphism of the angiotensin I-converting enzyme gene by capillary electrophoresis

1996 • 10 citations