Genome-wide scans of three independent sets of 90 Irish multiplex schizophrenia families and follow-up of selected regions in all families provides evidence for multiple susceptibility genes

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1995 • 5,291 citations

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Schizophrenia: The epigenetic puzzle

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Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

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1990 • 730 citations

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1988 • 624 citations

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Location of a Major Susceptibility Locus for Familial Schizophrenia on Chromosome 1q21-q22

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1993 • 493 citations

A potential vulnerability locus for schizophrenia on chromosome 6p24–22: evidence for genetic heterogeneity

1995 • 465 citations

Sequential strategy to identify a susceptibility gene for schizophrenia: Report of potential linkage on chromosome 22q12‐q13.1: Part 1

1994 • 387 citations

An international two–stage genome–wide search for schizophrenia susceptibility genes

1995 • 385 citations

Chromosome 1 loci in Finnish schizophrenia families

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H215O PET validation of steady-state arterial spin tagging cerebral blood flow measurements in humans

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The Structured Interview for Schizotypy (SIS): A Preliminary Report

1989 • 291 citations

A Genomewide Screen for Schizophrenia Genes in an Isolated Finnish Subpopulation, Suggesting Multiple Susceptibility Loci

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1995 • 279 citations

Genome scan of European-American schizophrenia pedigrees: Results of the NIMH genetics initiative and millennium consortium

1998 • 278 citations

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1998 • 269 citations

Genetic mapping using haplotype, association and linkage methods suggests a locus for severe bipolar disorder (BPI) at 18q22-q23

1996 • 260 citations

Schizophrenia: A genome scan targets chromosomes 3p and 8p as potential sites of susceptibility genes

1995 • 258 citations

A genome-wide search for schizophrenia susceptibility genes

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Suggestive Evidence for a Schizophrenia Susceptibility Locus on Chromosome 6q and a Confirmation in an Independent Series of Pedigrees

1997 • 234 citations

A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12

1996 • 232 citations

Linkage of Familial Schizophrenia to Chromosome 13q32

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Genome-wide scan for schizophrenia in the Finnish population: evidence for a locus on chromosome 7q22

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Evidence for a schizophrenia vulnerability locus on chromosome 8p in the Irish Study of High-Density Schizophrenia Families

1996 • 204 citations

Multicenter Linkage Study of Schizophrenia Candidate Regions on Chromosomes 5q, 6q, 10p, and 13q: Schizophrenia Linkage Collaborative Group III

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Genomic structure and localisation within a linkage hotspot of Disrupted In Schizophrenia 1, a gene disrupted by a translocation segregating with schizophrenia

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Support for a possible schizophrenia vulnerability locus in region 5q22–31 in Irish families

1997 • 192 citations

The Power to Detect Linkage in Complex Disease by Means of Simple LOD-Score Analyses

1998 • 191 citations

Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the ?7-nicotinic acetylcholine receptor subunit gene (CHRNA7)

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Seminars in Psychiatric Genetics

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Genomic scan for genes predisposing to schizophrenia

1994 • 170 citations

The Roscommon Family Study

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Significance Levels in Complex Inheritance

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Susceptibility genes for nicotine dependence: a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study

1999 • 159 citations

Neurobiology of schizophrenia

1997 • 157 citations

Evidence suggestive of a locus on chromosome 5q31 contributing to susceptibility for schizophrenia in German and Israeli families by multipoint affected sib-pair linkage analysis

1997 • 157 citations

Genomewide Scan for Familial Combined Hyperlipidemia Genes in Finnish Families, Suggesting Multiple Susceptibility Loci Influencing Triglyceride, Cholesterol, and Apolipoprotein B Levels

1999 • 156 citations

Genotypic association between the dopamine D3 receptor and tardive dyskinesia in chronic schizophrenia

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A Microsatellite Genetic Linkage Map of Human Chromosome 18

1993 • 153 citations

Linkage and associated studies of schizophrenia

2000 • 151 citations

The Roscommon Family Study

1993 • 150 citations

No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity

1996 • 149 citations

A schizophrenia locus may be located in region 10p15-p11

1998 • 148 citations

Support for a Chromosome 18p Locus Conferring Susceptibility to Functional Psychoses in Families with Schizophrenia, by Association and Linkage Analysis

1998 • 145 citations

Genetic Approaches to Mental Disorders

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Direct Power Comparisons between Simple LOD Scores and NPL Scores for Linkage Analysis in Complex Diseases

1999 • 132 citations

Refutation of the general single-locus model for the etiology of schizophrenia.

1982 • 131 citations

Further investigation of a chromosome 15 locus in schizophrenia: Analysis of affected sibpairs from the NIMH genetics initiative

1998 • 129 citations

Analysis of chromosome 22 markers in nine schizophrenia pedigrees

1994 • 128 citations

Magnitude of type I error when single-locus linkage analysis is maximized over models: a simulation study.

1997 • 127 citations

Further evidence for a susceptibility locus on chromosome 10p14-p11 in 72 families with schizophrenia by nonparametric linkage analysis.

1998 • 112 citations

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13q14.1-q32

1995 • 107 citations

Exclusion of a schizophrenia susceptibility gene from the chromosome 5q11-q13 region: new data and a reanalysis of previous reports.

1990 • 105 citations

Turning point in the design of linkage studies of schizophrenia

1994 • 104 citations

Irish study of high-density schizophrenia families: Field methods and power to detect linkage

1996 • 104 citations

Further evidence for a susceptibility locus on chromosome 10p14-p11 in 72 families with schizophrenia by nonparametric linkage analysis

1998 • 98 citations

Suggestive evidence for linkage of schizophrenia to markers on chromosome 13 in Caucasian but not Oriental populations

1997 • 92 citations

Linkage studies on chromosome 22 in familial schizophrenia

1995 • 87 citations

Bayesian Linkage Analysis, or: How I Learned to Stop Worrying and Love the Posterior Probability of Linkage

1998 • 87 citations

Second stage of a genome scan of schizophrenia: Study of five positive regions in an expanded sample

2000 • 80 citations

CAT scans, PET scans, and genomic scans

1998 • 79 citations

Genetic Dissection of Complex Traits

2002 • 78 citations

Search for linkage to schizophrenia on the X and Y chromosomes

1994 • 76 citations

Evidence for a chromosome 2p13–14 schizophrenia susceptibility locus in families from Palau, Micronesia

1998 • 76 citations

Multi-Locus Nonparametric Linkage Analysis of Complex Trait Loci with Neural Networks

1998 • 75 citations

A linkage study of schizophrenia to markers within Xp11 near the MAOB gene

1997 • 73 citations

6p24-22 region and major psychoses in the Eastern Quebec population. Le Groupe IREP.

1997 • 70 citations

6p24–22 Region and Major Psychoses in the Eastern Quebec Population

1997 • 63 citations

Methods of Linkage Analysis—and the Assumptions Underlying Them

1998 • 63 citations

Searching for schizophrenia genes

2001 • 63 citations

Genetically Mediated Vulnerability to Schizophrenia

1993 • 62 citations

Evidence of a locus for schizophrenia and related disorders on the short arm of chromosome 5 in a large pedigree

1996 • 56 citations

An epidemiologic, clinical, and family study of simple schizophrenia in County Roscommon, Ireland

1994 • 53 citations

Linkage analysis of a large swedish kindred provides further support for a susceptibility locus for schizophrenia on chromosome 6p23

1999 • 51 citations

Dissecting the genetic complexity of schizophrenia

1997 • 50 citations

Problems in the Definition, Interpretation, and Evaluation of Genetic Heterogeneity

2001 • 45 citations

Effect of genetic architecture on the power of human linkage studies to resolve the contribution of quantitative trait loci

1994 • 43 citations

1996 William Allan Award Address. Algorithms and inferences: the challenge of multifactorial diseases.

1997 • 41 citations

A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12

1998 • 41 citations

Optimal Ascertainment Strategies to Detect Linkage to Common Disease Alleles

1998 • 40 citations

23 On the resolution and feasibility of genome scanning approaches

2001 • 39 citations

Power of the linkage test for a heterogeneous disorder due to two independent inherited causes: A simulation study

1990 • 34 citations

Linkage studies of schizophrenia: A simulation study of statistical power

1992 • 31 citations

Functional correlates of nicotine administration: similarity with drugs of abuse

1998 • 25 citations

The putative schizophrenia locus on chromosome 6p: a brief overview of the linkage studies.

1996 • 21 citations

Power to detect linkage with heterogeneity in samples of small nuclear families

1993 • 14 citations

Analysis of epistasis in linked regions in the Irish study of high‐density schizophrenia families

2001 • 9 citations

X-Chromosome workshop

1998 • 8 citations

Genome scan of schizophrenia: Results of genotyping of positive regions.

1999 • 2 citations

Genome wide linkage anlaysis supports the presence of two separate susceptibility loci on chromosome 1q32 for biopolar disorder and 1q21-22.3 for schizophrenia

2000 • 1 citations

Deleted Work

1955 • 0 citations