Essential Role of Dopamine D₂Receptor in the Maintenance of Wakefulness, But Not in Homeostatic Regulation of Sleep, in Mice

The Mouse Brain in Stereotaxic Coordinates

2001 • 12,804 citations

Dopamine Receptors: From Structure to Function

1998 • 3,489 citations

Hypothalamic regulation of sleep and circadian rhythms

2005 • 2,613 citations

Dopaminergic Modulation of Neuronal Excitability in the Striatum and Nucleus Accumbens

2000 • 916 citations

Recent Advances in the Molecular Biology of Dopamine Receptors

1993 • 768 citations

Dopaminergic Role in Stimulant-Induced Wakefulness

2001 • 763 citations

Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine

2005 • 606 citations

Arousal effect of orexin A depends on activation of the histaminergic system

2001 • 540 citations

Parkinson’s disease and sleepiness

2002 • 507 citations

Anatomical, Physiological, and Pharmacological Characteristics of Histidine Decarboxylase Knock-Out Mice: Evidence for the Role of Brain Histamine in Behavioral and Sleep–Wake Control

2002 • 472 citations

Locomotor Activity in D2 Dopamine Receptor-Deficient Mice Is Determined by Gene Dosage, Genetic Background, and Developmental Adaptations

1998 • 448 citations

Identification of Wake-Active Dopaminergic Neurons in the Ventral Periaqueductal Gray Matter

2006 • 435 citations

Behavioral State Instability in Orexin Knock-Out Mice

2004 • 387 citations

Adenosine A2A receptors and basal ganglia physiology

2007 • 362 citations

Variations in extracellular levels of dopamine, noradrenaline, glutamate, and aspartate across the sleep–wake cycle in the medial prefrontal cortex and nucleus accumbens of freely moving rats

2005 • 309 citations

The roles of dopamine and serotonin, and of their receptors, in regulating sleep and waking

2008 • 267 citations

Activity of mesencephalic dopamine and non-dopamine neurons across stages of sleep and waking in the rat

1983 • 265 citations

An adenosine A2a agonist increases sleep and induces Fos in ventrolateral preoptic neurons

2001 • 263 citations

Dopaminergic D₁and D₂Receptors Are Essential for the Arousal Effect of Modafinil

2008 • 219 citations

Dominant localization of prostaglandin D receptors on arachnoid trabecular cells in mouse basal forebrain and their involvement in the regulation of non-rapid eye movement sleep

2001 • 190 citations

Increased dopaminergic transmission mediates the wake-promoting effects of CNS stimulants.

1998 • 184 citations

Altered sleep–wake characteristics and lack of arousal response to H ₃ receptor antagonist in histamine H ₁ receptor knockout mice

2006 • 179 citations

Biphasic effects of dopamine D-2 receptor agonists on sleep and wakefulness in the rat

1988 • 169 citations

Promotion of sleep mediated by the A2a-adenosine receptor and possible involvement of this receptor in the sleep induced by prostaglandin D2 in rats.

1996 • 162 citations

Variations in extracellular monoamines in the prefrontal cortex and medial hypothalamus after modafinil administration: a microdialysis study in rats

2001 • 148 citations

Sleep and its homeostatic regulation in mice lacking the adenosine A₁ receptor

2003 • 145 citations

Lipocalin-type prostaglandin D synthase produces prostaglandin D ₂ involved in regulation of physiological sleep

2006 • 144 citations

Wake-Promoting Actions of Dopamine D1 and D2 Receptor Stimulation

2003 • 119 citations

An adenosine A_2A receptor agonist induces sleep by increasing GABA release in the tuberomammillary nucleus to inhibit histaminergic systems in rats

2005 • 118 citations

Norepinephrine-Deficient Mice Exhibit Normal Sleep-Wake States but have Shorter Sleep Latency after Mild Stress and Low Doses of Amphetamine

2003 • 95 citations

Modafinil enhances extracellular levels of dopamine in the nucleus accumbens and increases wakefulness in rats

2006 • 93 citations

Algorithm for sleep scoring in experimental animals based on fast Fourier transform power spectrum analysis of the electroencephalogram

2008 • 91 citations

Differential effects of dopamine D-1 and D-2 receptor antagonist antipsychotics on sleep-wake patterns in the rat.

1993 • 86 citations

Sleep–wake behavior and responses of interleukin-6-deficient mice to sleep deprivation

2004 • 83 citations

Changes in EEG spectral power in the prefrontal cortex of conscious rats elicited by drugs interacting with dopaminergic and noradrenergic transmission

1999 • 83 citations

Opposite changes in adenosine A1 and A2A receptor mRNA in the rat following sleep deprivation

2001 • 80 citations

Impaired light masking in dopamine D2 receptor–null mice

2006 • 72 citations

Effects of ritanserin on sleep disturbances of dysthymic patients

1988 • 67 citations

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice

2004 • 62 citations

Dopamine 02 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary

1996 • 51 citations

Neurotoxic N-methyl-d-aspartate lesion of the ventral midbrain and mesopontine junction alters sleep–wake organization

1999 • 46 citations

D1/D2 receptor-targeting L-stepholidine, an active ingredient of the Chinese herb Stephonia, induces non-rapid eye movement sleep in mice

2009 • 32 citations

Piribedil‐induced sleep attacks in Parkinson's disease

2003 • 27 citations