Cisplatin resistance is associated with reduced interferon-γ-sensitivity and increased HER-2 expression in cultured ovarian carcinoma cells

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

Antibody to HER-2/neu receptor blocks DNA repair after cisplatin in human breast and ovarian cancer cells.

1994 • 439 citations

Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance.

1990 • 393 citations

A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell lines.

1991 • 229 citations

Intraperitoneal recombinant interferon gamma in ovarian cancer patients with residual disease at second-look laparotomy.

1996 • 158 citations

Cooperative Role of Interferon Regulatory Factor 1 and p91 (STAT1) Response Elements in Interferon-γ-inducible Expression of Human Indoleamine 2,3-Dioxygenase Gene

1996 • 155 citations

p185c-erbB-2 signal enhances cisplatin-induced cytotoxicity in human breast carcinoma cells: association between an oncogenic receptor tyrosine kinase and drug-induced DNA repair.

1994 • 131 citations

Cross-resistance to diverse drugs is associated with primary cisplatin resistance in ovarian cancer cell lines.

1993 • 129 citations

Sensitization of HER-2/neu-overexpressing non-small cell lung cancer cells to chemotherapeutic drugs by tyrosine kinase inhibitor emodin.

1996 • 113 citations

Enhancement of chemosensitivity by tyrphostin AG825 in high-p185(neu) expressing non-small cell lung cancer cells.

1996 • 89 citations

Gamma-interferon reduces expression of the protooncogene c-erbB-2 in human ovarian carcinoma cells.

1990 • 56 citations

Effects of retinoic acid and gamma-interferon on expression of retinoic acid receptor and cellular retinoic acid-binding protein in breast cancer cells.

1995 • 50 citations

Tumour cells surviving in vivo cisplatin chemotherapy display elevated c-myc expression

1996 • 42 citations

Effects of biological response modifiers on ovarian carcinoma cell lines.

1989 • 38 citations

Cell Biological Markers of Drug Resistance in Ovarian Carcinoma

1995 • 27 citations

Modulation of cisplatin cytotoxicity by human recombinant interferon-γ in human ovarian cancer cell lines

1994 • 24 citations

Development of resistance to cisplatin is associated with decreased expression of the gp185c-erbB-2 protein and alterations in growth properties and responses to therapy in an ovarian tumor cell line.

1994 • 15 citations

Functional differences in the promoters of the interferon‐inducible (2′‐5′)A oligoadenylate synthetase and 6–16 genes in interferon‐resistant Daudi cells

1994 • 14 citations

Intraperitoneal recombinant interferongamma in ovarian cancer patients with residual disease at second look laparotomy

1995 • 11 citations

Characterization of an Interferon-Resistant Mutant of the Human Breast Cancer Cell Line BT-20

1987 • 5 citations

Cell biological markers of drug resistance in ovarian carcinoma

1996 • 3 citations