Gamma-interferon reduces expression of the protooncogene c-erbB-2 in human ovarian carcinoma cells.

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/ neu Oncogene

1987 • 11,429 citations

INTERFERONS AND THEIR ACTIONS

1987 • 1,838 citations

Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor

1986 • 1,226 citations

The neu oncogene encodes an epidermal growth factor receptor-related protein

1986 • 1,131 citations

p185^HER2 Monoclonal Antibody Has Antiproliferative Effects In Vitro and Sensitizes Human Breast Tumor Cells to Tumor Necrosis Factor

1989 • 672 citations

Close link between reduction of c-myc expression by interferon and G0/G1 arrest

1985 • 358 citations

Egf binding to its receptor triggers a rapid tyrosine phosphorylation of the erbB-2 protein in the mammary tumor cell line SK-BR-3.

1988 • 226 citations

Expression of the c‐erbB‐2 protein in normal and transformed cells

1987 • 197 citations

Selective reduction of c-myc mRNA in Daudi cells by human beta interferon.

1984 • 142 citations

Differential regulation of interferon‐induced mRNAs and c‐myc mRNA by α‐ and γ‐interferons

1985 • 110 citations

Overexpression of the c‐erbB‐2 protein in human breast tumor cell lines

1989 • 106 citations

Collaborative phase I-II study of recombinant DNA-produced leukocyte interferon (clone A) in metastatic breast cancer, malignant lymphoma, and multiple myeloma

1984 • 102 citations

Modulation of epidermal growth factor receptors by human alpha interferon.

1986 • 58 citations

Growth factors and oncogenes

1985 • 55 citations

Effects of biological response modifiers on ovarian carcinoma cell lines.

1989 • 38 citations

Development of transformed phenotype induced by a human ras oncogene is inhibited by interferon

1985 • 33 citations

Intraperitoneal administration of human recombinant interferon-alpha in patients with ovarian cancer: effects on lymphocyte phenotype and cytotoxicity.

1988 • 24 citations

Recombinant DNA human interferon alpha 2 in advanced breast cancer: A phase 2 trial

1985 • 24 citations

Effects of human lymphoblastoid interferon on cultured breast cancer cells

1981 • 22 citations