Heterogeneous Assembly of Complementary Peptide Pairs into Amyloid Fibrils with α-β Structural Transition

Prions

1998 • 5,102 citations

Thioflavine T interaction with synthetic Alzheimer's disease β‐amyloid peptides: Detection of amyloid aggregation in solution

1993 • 2,137 citations

Protein misfolding, evolution and disease

1999 • 1,948 citations

MODELS OF AMYLOID SEEDING IN ALZHEIMER'S DISEASE AND SCRAPIE: Mechanistic Truths and Physiological Consequences of the Time-Dependent Solubility of Amyloid Proteins

1997 • 1,621 citations

Translating cell biology into therapeutic advances in Alzheimer's disease

1999 • 1,592 citations

Amyloid fibrillogenesis: themes and variations

2000 • 1,082 citations

The alternative conformations of amyloidogenic proteins and their multi-step assembly pathways

1998 • 996 citations

β-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: Implications for Alzheimer's therapy

1998 • 839 citations

Responsive gels formed by the spontaneous self-assembly of peptides into polymeric β-sheet tapes

1997 • 838 citations

The Structure of Amyloid Fibrils by Electron Microscopy and X-Ray Diffraction

1997 • 740 citations

Self-complementary oligopeptide matrices support mammalian cell attachment

1995 • 670 citations

Amphiphilic Secondary Structure: Design of Peptide Hormones

1984 • 541 citations

Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing

1999 • 509 citations

Structural model for the β-amyloid fibril based on interstrand alignment of an antiparallel-sheet comprising a C-terminal peptide

1995 • 393 citations

Propagating structure of Alzheimer’s β-amyloid _(10–35) is parallel β-sheet with residues in exact register

1998 • 386 citations

Physical, Morphological and Functional Differences between pH 5.8 and 7.4 Aggregates of the Alzheimer's Amyloid Peptide A β

1996 • 329 citations

Protofilaments, Filaments, Ribbons, and Fibrils from Peptidomimetic Self-Assembly: Implications for Amyloid Fibril Formation and Materials Science

2000 • 280 citations

Direct conversion of an oligopeptide from a β-sheet to an α-helix: A model for amyloid formation

1997 • 192 citations

X-ray Diffraction of Scrapie Prion Rods and PrP Peptides

1995 • 165 citations

Engineering of peptide β-sheet nanotapes

1997 • 156 citations

Self-Assembly of Aβ_(10-35)-PEG Block Copolymer Fibrils

1999 • 133 citations

Discrete intermediates versus molten globule models for protein folding: characterization of partially folded intermediates of apomyoglobin

1998 • 112 citations

Application of dimethylsulphoxide(DMSO) / trifluoroacetic acid(TFA) oxidation to the synthesis of cystine-containing peptide

1991 • 74 citations

Design of a Peptide Undergoing α-β Structural Transition and Amyloid Fibrillogenesis by the Introduction of a Hydrophobic Defect

1998 • 61 citations

Optimization of Hydrophobic Domains in Peptides that Undergo Transformation from α-Helix to β-Fibril

1999 • 50 citations

Mutational analysis of designed peptides that undergo structural transition from α helix to β sheet and amyloid fibril formation

2000 • 40 citations

Construction of Peptides That Undergo Structural Transition from α-Helix to β-Sheet and Amyloid Fibril Formation by the Introduction of N-Terminal Hydrophobic Amino Acids

2000 • 28 citations