Cell Adhesion Regulates the Interaction between Nck and p21-activated Kinase

Rho Family GTPases Regulate p38 Mitogen-activated Protein Kinase through the Downstream Mediator Pak1

1995 • 733 citations

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

1997 • 687 citations

Integrin signaling and cell growth control

1998 • 655 citations

Cdc42 and PAK-mediated Signaling Leads to Jun Kinase and p38 Mitogen-activated Protein Kinase Activation

1995 • 639 citations

Activation of Rac and Cdc42 by Integrins Mediates Cell Spreading

1998 • 638 citations

Expression of Constitutively Active α-PAK Reveals Effects of the Kinase on Actin and Focal Complexes

1997 • 560 citations

Actin machinery: pushing the envelope

2000 • 458 citations

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK

2000 • 454 citations

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

1998 • 435 citations

Fibronectin-Stimulated Signaling from a Focal Adhesion Kinase–c-Src Complex: Involvement of the Grb2, p130^cas, and Nck Adaptor Proteins

1997 • 432 citations

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

1997 • 422 citations

Identification of a Mouse p21Cdc42/Rac Activated Kinase

1995 • 395 citations

PAK to the future

1999 • 391 citations

Insulin signal transduction through protein kinase cascades.

1998 • 364 citations

Interaction of the Nck Adapter Protein with p21-activated Kinase (PAK1)

1996 • 309 citations

A Role for P21-Activated Kinase in Endothelial Cell Migration

1999 • 295 citations

Actions of Rho Family Small G Proteins and p21-Activated Protein Kinases on Mitogen-Activated Protein Kinase Family Members

1996 • 275 citations

The adaptor protein Nck links receptor tyrosine kinases with the serine-threonine kinase Pak1

1996 • 268 citations

p21-Activated protein kinase: a crucial component of morphological signaling?

1999 • 261 citations

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck

1997 • 259 citations

Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

2000 • 210 citations

A GTPase-independent Mechanism of p21-activated Kinase Activation

1998 • 204 citations

Cell Anchorage Permits Efficient Signal Transduction Between Ras and Its Downstream Kinases

1997 • 192 citations

The p21Rac/Cdc42-activated kinases (PAKs)

1998 • 190 citations

Interaction between PAK and Nck: a Template for Nck Targets and Role of PAK Autophosphorylation

2000 • 149 citations

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

1998 • 124 citations

The Nck SH2/SH3 adaptor protein: a regulator of multiple intracellular signal transduction events

1998 • 104 citations

Nckβ Adapter Regulates Actin Polymerization in NIH 3T3 Fibroblasts in Response to Platelet-Derived Growth Factor bb

2000 • 89 citations

Mechanism of activation of Pak1 kinase by membrane localization

1999 • 82 citations

Integrins Enhance Platelet-derived Growth Factor (PDGF)-dependent Responses by Altering the Signal Relay Enzymes That Are Recruited to the PDGF β Receptor

1999 • 80 citations

Induced direct binding of the adapter protein Nck to the GTPase-activating protein-associated protein p62 by epidermal growth factor

1997 • 33 citations

Adhesion signaling: PAK meets Rac on solid ground

2000 • 32 citations

Angiotensin II stimulates serine phosphorylation of the adaptor protein Nck: physical association with the serine/threonine kinases Pak1 and casein kinase I

1999 • 10 citations