Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor)

Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC

1997 • 3,847 citations

Functional interaction of β-catenin with the transcription factor LEF-1

1996 • 2,847 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

Functional Interaction of an Axin Homolog, Conductin, with β-Catenin, APC, and GSK3β

1998 • 1,241 citations

Stabilization of β-Catenin by Genetic Defects in Melanoma Cell Lines

1997 • 1,215 citations

Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas

1998 • 1,085 citations

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein.

1995 • 1,025 citations

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

1998 • 998 citations

Serine Phosphorylation-regulated Ubiquitination and Degradation of β-Catenin

1997 • 702 citations

A common human skin tumour is caused by activating mutations in β-catenin

1999 • 608 citations

Molecular Diagnosis of Familial Adenomatous Polyposis

1993 • 588 citations

Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene.

1999 • 398 citations

Sporadic medulloblastomas contain oncogenic beta-catenin mutations.

1998 • 395 citations

Beta-catenin mutation in carcinoma of the uterine endometrium.

1998 • 370 citations

Beta-catenin mutations in human prostate cancer.

1998 • 368 citations

Wnt-1 Regulates Free Pools of Catenins and Stabilizes APC-Catenin Complexes

1996 • 337 citations

Increased beta-catenin protein and somatic APC mutations in sporadic aggressive fibromatoses (desmoid tumors).

1997 • 320 citations

Frequent mutation and nuclear localization of betacatenin in anaplastic thyroid carcinoma

1999 • 303 citations

Frequent Nuclear/Cytoplasmic Localization of β-Catenin without Exon 3 Mutations in Malignant Melanoma

1999 • 278 citations

Activation of the beta-catenin gene by interstitial deletions involving exon 3 in primary colorectal carcinomas without adenomatous polyposis coli mutations.

1998 • 276 citations

A scoring system for immunohistochemical staining: consensus report of the task force for basic research of the EORTC-GCCG. European Organization for Research and Treatment of Cancer-Gynaecological Cancer Cooperative Group.

1997 • 198 citations

Desmoid fibromatosis is a clonal process

1996 • 161 citations

Aggressive Fibromatosis (Desmoid Tumor) is A Monoclonal Disorder

1997 • 138 citations

Aggressive fibromatosis (non-familial desmoid tumour): Therapeutic problems and the role of adjuvant radiotherapy

1995 • 135 citations

Adenomatous Polyposis Coli Gene Mutation Alters Proliferation through its β-Catenin-Regulatory Function in Aggressive Fibromatosis (Desmoid Tumor)

1998 • 130 citations

Mutations of adenomatous polyposis coli (APC) gene are uncommon in sporadic desmoid tumours

1998 • 101 citations

Aberrant expression and phosphorylation of β-catenin in human colorectal cancer

1998 • 85 citations

Quality control in immunocytochemistry: experiences with the oestrogen receptor assay.

1992 • 46 citations