Structure of the rabbit cytochrome P450IIC3 gene, a constitutive member of the P450IIC subfamily

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Single-stranded DNA ‘blue’ T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering

1986 • 816 citations

The 2.6-A crystal structure of Pseudomonas putida cytochrome P-450.

1985 • 815 citations

Lambdoid phages that simplify the recovery of in vitro recombinants

1977 • 779 citations

The evolution of genes: the chicken preproinsulin gene

1980 • 725 citations

Identification of a rat liver nuclear protein that binds to the enhancer core element of three animal viruses.

1987 • 631 citations

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

1989 • 545 citations

Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast.

1985 • 526 citations

Sequence diversity among related genes for recognition of specific targets in DNA molecules

1983 • 478 citations

The Role of Cis-Acting Promoter Elements in Tissue-Specific Albumin Gene Expression

1989 • 329 citations

Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters.

1988 • 323 citations

The construction in vitro of transducing derivatives of phage lambda

1976 • 258 citations

Nucleosomes will not form on double-stranded RNA or over poly(dA)-poly(dT) tracts in recombinant DNA

1981 • 244 citations

Evolution of cytochrome P-450 proteins.

1987 • 190 citations

Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver.

1985 • 150 citations

An improved DNA sequencing strategy

1985 • 148 citations

Distinguishing between mechanisms of eukaryotic transcriptional activation with bacteriophage T7 RNA polymerase

1987 • 141 citations

Single stranded DNA SP6 promoter plasmids for engineering mutant RNAs and proteins: synthesis of a ‘stretched’ preproparathyroid hormone

1985 • 135 citations

Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.

1983 • 133 citations

Identification of multiple regulatory elements on the human cytochrome P450IA1 gene

1988 • 122 citations

Structure and drug inducibility of the human cytochrome P-450c gene

1986 • 106 citations

Hepatocyte-specific promoter element HP1 of the Xenopus albumin gene interacts with transcriptional factors of mammalian hepatocytes

1988 • 105 citations

Isolation and sequence analysis of three cloned cDNAs for rabbit liver proteins that are related to rabbit cytochrome P-450 (form 2), the major phenobarbital-inducible form

1984 • 97 citations

Multiple gene-like sequences related to the rabbit hepatic progesterone 21-hydroxylase cytochrome P-450 1.

1985 • 86 citations

The complete amino acid sequence of a constitutive form of liver microsomal cytochrome P-450.

1985 • 78 citations

Isolation and characterization of a constitutive form of rabbit liver microsomal cytochrome P-450.

1980 • 70 citations

Functional and structural polymorphism of rabbit microsomal cytochrome P-450 form 3b.

1982 • 68 citations

Tissue-specificity of liver gene expression: a common liver-specific promoter element

1988 • 63 citations

Interference resistant mutants of phage f1

1982 • 62 citations

Gene structure and nucleotide sequence for rat cytochrome P-450c

1985 • 60 citations

Gene conversion in a cytochrome P-450 gene family.

1986 • 56 citations

Purification and properties of P-450lm3b, a constitutive form of cytochrome P-450, from rabbit liver microsomes

1979 • 48 citations

Gene structure of cytochrome P-450(M-1) specifically expressed in male rat liver

1987 • 47 citations

Differential induction and tissue-specific expression of closely related members of the phenobarbital-inducible rabbit cytochrome P-450 gene family.

1984 • 38 citations

Allosteric regulation of the 16 alpha-hydroxylation of progesterone as catalyzed by rabbit microsomal cytochrome P-450 3b.

1983 • 31 citations

Potentiation of 3-methylcholanthrene induction of rat hepatic cytochrome P450IA1 by dexamethasone in vivo.

1989 • 28 citations

Selection of Variable-Joining Region Combinations in the α Chain of the T Cell Receptor

1988 • 28 citations

Two catalytically distinct subforms of cytochrome P-450 3b as obtained from inbred rabbits

1985 • 22 citations

Structure of 5′ Regions and Expression of Phenobarbital-Inducible Rabbit Cytochrome P450IIC Genes

1990 • 22 citations

Use of a monoclonal antibody specific for rabbit microsomal cytochrome P-450 3b to characterize the participation of this cytochrome in the microsomal 6.beta.- and 16.alpha.-hydroxylation of progesterone

1984 • 21 citations

Structure of Genes in the Cytochrome P-450PBc Subfamily: Conservation of Intron Locations in the Phenobarbital-Inducible Family

1986 • 19 citations

Characterization of rabbit cytochrome P450IIC4 cDNA and induction by phenobarbital of related hepatic mRNA levels

1987 • 14 citations