Structure of Genes in the Cytochrome P-450PBc Subfamily: Conservation of Intron Locations in the Phenobarbital-Inducible Family

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Organization and Expression of Eucaryotic Split Genes Coding for Proteins

1981 • 4,730 citations

Colony hybridization: a method for the isolation of cloned DNAs that contain a specific gene.

1975 • 3,483 citations

A rapid boiling method for the preparation of bacterial plasmids

1981 • 3,334 citations

A system for shotgun DNA sequencing

1981 • 2,710 citations

The isolation of structural genes from libraries of eucaryotic DNA

1978 • 1,877 citations

Mapping of RNA by a modification of the Berk-Sharp procedure: the 5′ termini of 15 S β-globin mRNA precursor and mature 10 S β-globin mRNA have identical map coordinates

1979 • 1,286 citations

Biochemical Evolution

1977 • 1,283 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits.

1982 • 537 citations

Sequence diversity among related genes for recognition of specific targets in DNA molecules

1983 • 478 citations

EK2 Derivatives of Bacteriophage Lambda Useful in the Cloning of DNA from Higher Organisms: The λgt WES System

1977 • 415 citations

Genes-in-Pieces Revisited

1985 • 362 citations

Rat hepatic cytochrome P-450 isoenzyme 2c. Identification as a male-specific, developmentally induced steroid 16 alpha-hydroxylase and comparison to a female-specific cytochrome P-450 isoenzyme.

1984 • 268 citations

The construction in vitro of transducing derivatives of phage lambda

1976 • 258 citations

Sex difference of cytochrome P-450 in the rat: Purification, characterization, and quantitation of constitutive forms of cytochrome P-450 from liver microsomes of male and female rats

1983 • 233 citations

Definition of a novel promoter for the major adenovirus-associated virus mRNA

1980 • 187 citations

Gene structure of a major form of phenobarbital-inducible cytochrome P-450 in rat liver.

1985 • 150 citations

Complete amino acid sequence and predicted membrane topology of phenobarbital-induced cytochrome P-450 (isozyme 2) from rabbit liver microsomes.

1983 • 146 citations

A cytochrome P-450 multigene family. Characterization of a gene activated by phenobarbital administration.

1983 • 137 citations

Single stranded DNA SP6 promoter plasmids for engineering mutant RNAs and proteins: synthesis of a ‘stretched’ preproparathyroid hormone

1985 • 135 citations

Gene structure of a phenobarbital-inducible cytochrome P-450 in rat liver.

1983 • 133 citations

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

1983 • 132 citations

Distinct organization of methylcholanthrene- and phenobarbital-inducible cytochrome P-450 genes in the rat.

1984 • 130 citations

Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver.

1984 • 129 citations

Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC

1984 • 129 citations

Rapid isolation of RNA using proteinase K and sodium perchlorate

1979 • 117 citations

Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses.

1983 • 112 citations

Amino-terminal sequence of phenobarbital-inducible cytochrome P-450 from rabbit liver microsomes: Similarity to hydrophobic amino-terminal segments of preproteins

1977 • 104 citations

Complete nucleotide sequence of a methylcholanthrene-inducible cytochrome P-450 (P-450d) gene in the rat.

1985 • 104 citations

Isolation and sequence analysis of three cloned cDNAs for rabbit liver proteins that are related to rabbit cytochrome P-450 (form 2), the major phenobarbital-inducible form

1984 • 97 citations

Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.

1985 • 96 citations

Structure of a human smooth muscle actin gene (aortic type) with a unique intron site.

1984 • 91 citations

NH2-terminal sequence analyses of four rat hepatic microsomal cytochromes P-4501

1984 • 88 citations

Multiple gene-like sequences related to the rabbit hepatic progesterone 21-hydroxylase cytochrome P-450 1.

1985 • 86 citations

Cytochrome P450 gene expression and regulation

1985 • 85 citations

The complete amino acid sequence of a constitutive form of liver microsomal cytochrome P-450.

1985 • 78 citations

Isolation and characterization of full-length mouse cDNA and genomic clones of 3-methylcholanthrene-inducible cytochrome P1-450 and P3-450

1984 • 76 citations

Amino-terminal and carboxy-terminal sequence of hepatic microsomal cytochrome P-450d, a unique hemoprotein from rats treated with isosafrole

1982 • 66 citations

Multiplicity of deoxyribonucleic acid sequences with homology to a cloned complementary deoxyribonucleic acid coding for rat phenobarbital-inducible cytochrome P-450

1983 • 63 citations

Gene structure and nucleotide sequence for rat cytochrome P-450c

1985 • 60 citations

Induction of cytochrome P-450 by pregnenolone-16 alpha-carbonitrile in primary monolayer cultures of adult rat hepatocytes and in a cell-free translation system.

1981 • 59 citations

Differential induction and tissue-specific expression of closely related members of the phenobarbital-inducible rabbit cytochrome P-450 gene family.

1984 • 38 citations

On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes.

1984 • 36 citations

The induction of microsomal electron transport enzymes

1983 • 21 citations