Characterization of mRNA Endonucleases

Poly(A) elongation during Xenopus oocyte maturation is required for translational recruitment and is mediated by a short sequence element.

1989 • 412 citations

Poly(A) shortening and degradation of the 3' A+U-rich sequences of human c-myc mRNA in a cell-free system.

1988 • 324 citations

Control of c-myc mRNA half-life in vitro by a protein capable of binding to a coding region stability determinant.

1992 • 301 citations

Evidence that the pathway of transferrin receptor mRNA degradation involves an endonucleolytic cleavage within the 3′ UTR and does not involve poly(A) tail shortening.

1994 • 290 citations

H4 histone messenger RNA decay in cell-free extracts initiates at or near the 3′ terminus and proceeds 3′ to 5′

1986 • 179 citations

Assaying the Polyadenylation State of mRNAs

1999 • 159 citations

mRNA metabolism and post-transcriptional gene regulation

1997 • 129 citations

Purification and properties of a protein that binds to the C-terminal coding region of human c-myc mRNA.

1994 • 125 citations

Degradation of apolipoprotein II mRNA occurs via endonucleolytic cleavage at 5′-AAU-3′/5′-UAA-3′ elements in single-stranded loop domains of the 3′-noncoding region

1989 • 118 citations

Sequence-specific endonucleolytic cleavage and protection of mRNA in Xenopus and Drosophila.

1993 • 99 citations

Post-transcriptional regulation of groα, β, γ, and IL-8 mRNAs by IL-1β

1991 • 94 citations

RNA processing : a practical approach

1994 • 86 citations

A guanosine quadruplex and two stable hairpins flank a major cleavage site in insulin-like growth factor II mRNA

1994 • 82 citations

Endonucleolytic cleavage of a maternal homeo box mRNA in Xenopus oocytes.

1990 • 75 citations

3′-end labeling of RNA with recombinant yeast poly(A) polymerase

1993 • 68 citations

Purification and Characterization of an Estrogen-regulated Xenopus Liver Polysomal Nuclease Involved in the Selective Destabilization of Albumin mRNA

1995 • 65 citations

Removal of a 3′ non-coding sequence is an initial step in degradation of groα mRNA and is regulated by interleukin-1

1992 • 64 citations

Long-Range RNA Interaction of Two Sequence Elements Required for Endonucleolytic Cleavage of Human Insulin-Like Growth Factor II mRNAs

1995 • 55 citations

Specific endonucleolytic cleavage of IGF-II mRNAs

1991 • 52 citations

Coordinate Estrogen-Regulated Instability of Serum Protein-Coding Messenger RNAs inXenopus laevis

1991 • 48 citations

Method for Determining RNA 3' Ends and Application to Human Telomerase RNA

1996 • 43 citations

Cleavage properties of an estrogen-regulated polysomal ribonuclease involved in the destabilization of albumin mRNA

1997 • 43 citations

The Nuclease That Selectively Degrades Albumin mRNA in Vitro Associates with Xenopus Liver Polysomes through the 80S Ribosome Complex

1993 • 22 citations

The cis-acting elements involved in endonucleolytic cleavage of the 3' UTR of human IGF-II mRNAs bind a 50 kDa protein

1996 • 14 citations

Assays for Analyzing Exonucleasesin Vitro

1999 • 8 citations