A G‐protein‐coupled 130 kDa phospholipase C isozyme, PLC‐β4, from the particulate fraction of bovine cerebellum

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Inositol phosphates and cell signalling

1989 • 4,058 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

Studies of Inositol Phospholipid-Specific Phospholipase C

1989 • 914 citations

Regulation of Polyphosphoinositide-specific Phospholipase C Activity by Purified G _q

1991 • 886 citations

Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins

1991 • 774 citations

The Metabolism of Phosphoinositide-Derived Messenger Molecules

1986 • 717 citations

Isolation of a putative phospholipase c gene of drosophila, norpA, and its role in phototransduction

1988 • 665 citations

Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits

1992 • 630 citations

Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C

1992 • 506 citations

Role of phosphoinositides in transmembrane signaling.

1990 • 491 citations

Cloning and sequence of multiple forms of phospholipase C

1988 • 342 citations

Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells.

1992 • 321 citations

Activation of phospholipase C isozymes by G protein beta gamma subunits.

1993 • 306 citations

Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipases C from bovine brain.

1987 • 243 citations

Bovine brain cytosol contains three immunologically distinct forms of inositolphospholipid-specific phospholipase C.

1987 • 233 citations

Inositol phospholipid-specific phospholipase C: interaction of the γ isoform with tyrosine kinase

1991 • 233 citations

Cloning, sequencing, purification, and Gq-dependent activation of phospholipase C-beta 3.

1993 • 213 citations

Purification and characterization of two G-proteins that activate the beta 1 isozyme of phosphoinositide-specific phospholipase C. Identification as members of the Gq class.

1991 • 191 citations

Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits

1992 • 188 citations

Identification of critical regions on phospholipase C-beta 1 required for activation by G-proteins.

1993 • 179 citations

Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.

1992 • 176 citations

Removal of the carboxyl-terminal region of phospholipase C-beta 1 by calpain abolishes activation by G alpha q.

1993 • 158 citations

Determination of the primary structure of PLC-154 demonstrates diversity of phosphoinositide-specific phospholipase C activities

1988 • 155 citations

Purification of an AlF4- and G-protein beta gamma-subunit-regulated phospholipase C-activating protein

1991 • 135 citations

A Drosophila phospholipase C gene that is expressed in the central nervous system

1991 • 101 citations

Identification, purification and characterization of a novel phosphatidylinositol‐specific phospholipase C, a third member of the β subfamily

1992 • 33 citations

Proto-oncogenes in cell development

1992 • 32 citations