Development of an Internally Quenched Fluorescent Substrate Selective for Endothelin-Converting Enzyme-1

On the size of the active site in proteases. I. Papain

1967 • 5,150 citations

Enzyme structure and mechanism

1977 • 2,935 citations

Enzyme structure and mechanism

1978 • 2,897 citations

ECE-1: A membrane-bound metalloprotease that catalyzes the proteolytic activation of big endothelin-1

1994 • 932 citations

[23] Buffers of constant ionic strength for studying pH-dependent processes

1982 • 644 citations

Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones ¹

1989 • 552 citations

Dual genetic pathways of endothelin-mediated intercellular signaling revealed by targeted disruption of endothelin converting enzyme-1 gene

1998 • 488 citations

Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX

1997 • 395 citations

Cloning and functional expression of endothelin-converting enzyme from rat endothelial cells

1994 • 291 citations

Human kidney "enkephalinase", a neutral metalloendopeptidase that cleaves active peptides

1983 • 286 citations

Purification and characterization of endothelin-converting enzyme from rat lung.

1993 • 154 citations

Hydrolysis of Peptide Hormones by Endothelin-converting Enzyme-1

1999 • 143 citations

Purification and characterization of a phosphoramidon-sensitive endothelin-converting enzyme in porcine aortic endothelium. OFF.

1993 • 134 citations

Novel activity of endothelin-converting enzyme: hydrolysis of bradykinin

1997 • 106 citations

[2] Fluorimetric assays of proteolytic enzymes

1995 • 100 citations

Comparison of the subsite specificity of the mammalian neutral endopeptidase 24.11 (enkephalinase) to the bacterial neutral endopeptidase thermolysin.

1986 • 94 citations

Spectrophotometric assay for vertebrate collagenase

1985 • 91 citations

XCE, a new member of the endothelin-converting enzyme and neutral endopeptidase family, is preferentially expressed in the CNS

1999 • 89 citations

Novel Selective Quinazoline Inhibitors of Endothelin Converting Enzyme-1

1998 • 44 citations

Soluble Human Endothelin-Converting Enzyme-1: Expression, Purification, and Demonstration of Pronounced pH Sensitivity

1998 • 37 citations

Endothelin Converting Enzyme Inhibitors

1997 • 37 citations

Inhibitor Potencies and Substrate Preference for Endothelin-Converting Enzyme-1 are Dramatically Affected by PH

2000 • 33 citations

Disulfide Bonds in Big ET-1 Are Essential for the Specific Cleavage at the Trp21–Val22 Bond by Soluble Endothelin Converting Enzyme-1 from Baculovirus/Insect Cells

2000 • 17 citations