The Search for Human Obesity Genes

Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results

1995 • 5,291 citations

Environmental Contributions to the Obesity Epidemic

1998 • 2,243 citations

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1997 • 1,647 citations

Genetic and environmental factors in relative body weight and human adiposity.

1997 • 1,486 citations

A leptin missense mutation associated with hypogonadism and morbid obesity

1998 • 1,187 citations

Leptin Increases Hypothalamic Pro-opiomelanocortin mRNA Expression in the Rostral Arcuate Nucleus

1997 • 837 citations

Extreme Discordant Sib Pairs for Mapping Quantitative Trait Loci in Humans

1995 • 532 citations

A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2

1997 • 443 citations

Obesity: Theory and Therapy

1993 • 234 citations

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q.

1997 • 232 citations

Linkage Between Markers in the Vicinity of the Uncoupling Protein 2 Gene and Resting Metabolic Rate in Humans

1997 • 227 citations

Comparison of Effect Estimates from a Meta-Analysis of Summary Data from Published Studies and from a Meta-Analysis Using Individual Patient Data for Ovarian Cancer Studies

1997 • 150 citations

Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group.

1997 • 139 citations

Quantitative variation in obesity-related traits and insulin precursors linked to the OB gene region on human chromosome 7.

1996 • 121 citations

A paired sibling analysis of the beta-3 adrenergic receptor and obesity in Mexican Americans.

1998 • 110 citations

Segregation analysis of fat mass and other body composition measures derived from underwater weighing.

1993 • 96 citations

The Human Obesity Gene Map: The 1997 Update

1998 • 88 citations

Genetic dissection of obesity in polygenic animal models.

1997 • 84 citations

Meta-Analysis of Linkage Data under Worst-Case Conditions: A Demonstration Using the Human OB Region

1998 • 82 citations

Statistical properties of a variance components method for quantitative trait linkage analysis in nuclear families and extended pedigrees

1997 • 72 citations

Extreme Selection Strategies in Gene Mapping Studies of Oligogenic Quantitative Traits Do Not Always Increase Power

1998 • 71 citations

Recessive inheritance of a relative fat pattern.

1989 • 57 citations

Genetic and environmental correlations among hormone levels and measures of body fat accumulation and topography.

1996 • 56 citations

Role of the agouti gene in obesity

1997 • 55 citations

Within birth cohort segregation analyses support recessive inheritance of body mass index in white and African-American families.

1996 • 14 citations

Special issue on the genetics of obesity.

1997 • 3 citations