Evidence that interleukin-1 and phorbol esters activate NF-kappa B by different pathways: role of protein kinase C.

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Multiple nuclear factors interact with the immunoglobulin enhancer sequences

1986 • 2,771 citations

Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide-dependent protein kinase and protein kinase C

1984 • 2,728 citations

IκB: a Specific Inhibitor of the NF-κB Transcription Factor

1988 • 2,203 citations

Turnover of Inositol Phospholipids and Signal Transduction

1984 • 1,629 citations

NF-κB: A pleiotropic mediator of inducible and tissue-specific gene control

1989 • 1,622 citations

Activation in vitro of NF-κB" by phosphorylation of its inhibitor IκB"

1990 • 1,202 citations

Purified human IκB can rapidly dissociate the complex of the NF-κB transcription factor with its cognate DNA

1990 • 445 citations

In Vitro Activation and Nuclear Translocation of NF-κB Catalyzed by Cyclic AMP-Dependent Protein Kinase and Protein Kinase C

1989 • 389 citations

Murine B Cell Leukemia Line with Inducible Surface Immunoglobulin Expression

1978 • 388 citations

Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes.

1989 • 256 citations

In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.

1989 • 220 citations

Binding and internalization of interleukin 1 by T cells. Direct evidence for high- and low-affinity classes of interleukin 1 receptor.

1986 • 194 citations

Protein kinase C-independent activation of nuclear factor kappa B by tumor necrosis factor.

1990 • 193 citations

Evidence for different interleukin 1 receptors in murine B- and T-cell lines.

1989 • 186 citations

Interleukin 1 and cyclic AMP induce kappa immunoglobulin light-chain expression via activation of an NF-kappa B-like DNA-binding protein.

1989 • 176 citations

Interferon-gamma-induced transcriptional activation is mediated by protein kinase C.

1988 • 137 citations

Lipopolysaccharide and phorbol esters induce differentiation but have opposite effects on phosphatidylinositol turnover and Ca2+ mobilization in 70Z/3 pre-B lymphocytes.

1985 • 119 citations

Interleukin 1 and tumour necrosis factor increase phosphorylation of the small heat shock protein

1989 • 117 citations

IL-1 and TNF transmodulate epidermal growth factor receptors by a protein kinase C-independent mechanism.

1989 • 116 citations

Isoquinolinesulfonamides, Novel and Potent Inhibitors of Cyclic Nucleotide-Dependent Protein Kinase and Protein Kinase C

1984 • 98 citations

Interferon-gamma and interleukin-1 alpha induce transient translocation of protein kinase C activity to membranes in a B lymphoid cell line. Evidence for a protein kinase C-independent pathway in lymphokine-induced cytoplasmic alkalinization.

1988 • 75 citations

Induction of κ Transcription by Interferon-γ Without Activation of NF-κB

1988 • 75 citations

IL-1 induces rapid phosphorylation of the IL-1 receptor.

1989 • 74 citations

Purification and characterization of a cytosolic 65-kilodalton phosphoprotein in human leukocytes whose phosphorylation is augmented by stimulation with interleukin 1

1988 • 73 citations

Role of cAMP in interleukin-1-induced kappa light chain gene expression in murine B cell line.

1990 • 69 citations

Interleukin 1 and Cyclic AMP Induce κ Immunoglobulin Light-Chain Expression via Activation of an NF-κB-Like DNA-Binding Protein

1989 • 57 citations

Induction of Interleukin-2 Receptor-α Gene Expression Is Regulated by Post-translational Activation of κ B Specific DNA Binding Proteins

1989 • 32 citations

Inhibition of T-Cell Antigen Receptor-Mediated Transmembrane Signaling by Protein Kinase C Activation

1988 • 32 citations

Recombinant human interleukin 1-stimulated Na+/H+ exchange is not required for differentiation in pre-B lymphocyte cell line, 70Z/3.

1987 • 29 citations

The Family of Protein Kinase C: Its Molecular Heterogeneity and Differential Expression

1988 • 29 citations

Recombinant murine interferon-gamma-induced differentiation of pre-B lymphocytes is associated with Na+/H+ exchange-dependent and -independent cytoplasmic alkalinization.

1988 • 22 citations

Inhibition of T-cell antigen receptor-mediated transmembrane signaling by protein kinase C activation.

1988 • 21 citations

A gamma interferon-unresponsive variant of cell line 70Z/3, IFN-4, can be partially rescued by phorbol myristate acetate.

1989 • 14 citations

A Gamma Interferon-Unresponsive Variant of Cell Line 70Z/3, IFN-4, Can Be Partially Rescued by Phorbol Myristate Acetate

1989 • 6 citations