Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Recombinant Genomes Which Express Chloramphenicol Acetyltransferase in Mammalian Cells

1982 • 3,106 citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

1987 • 3,057 citations

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

1987 • 2,107 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Transcription factor AP-2 mediates induction by two different signal-transduction pathways: Protein kinase C and cAMP

1987 • 1,391 citations

Human Proto-Oncogene c- jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

1987 • 1,353 citations

Affinity purification of sequence-specific DNA binding proteins.

1986 • 1,255 citations

Oncogene jun encodes a sequence-specific trans- activator similar to AP-1

1988 • 940 citations

Identification of a Putative Regulator of Early T Cell Activation Genes

1988 • 933 citations

Trans-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses.

1988 • 736 citations

High efficiency polyoma DNA transfection of chloroquine treated cells

1983 • 711 citations

HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor

1988 • 607 citations

Characterization of antigen receptor response elements within the interleukin-2 enhancer.

1988 • 451 citations

Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters

1987 • 379 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

Structure of the chromosomal gene for granulocyte-macrophage colony stimulating factor: comparison of the mouse and human genes.

1985 • 257 citations

Cell type-specificity elements of the immunoglobulin heavy chain gene enhancer.

1987 • 255 citations

Discrete elements within the SV40 enhancer region display different cell-specific enhancer activities.

1987 • 240 citations

‘B-cell factors’ are pleiotropic

1988 • 230 citations

Molecular Biology of Interleukin 4 and Interleukin 5 Genes and Biology of their Products that Stimulate B Cells, T Cells and Hemopoietic Cells

1988 • 211 citations

A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor.

1987 • 174 citations

Promoter region of interleukin-2 gene undergoes chromatin structure changes and confers inducibility on chloramphenicol acetyltransferase gene during activation of T cells.

1986 • 171 citations

Characterization of Antigen Receptor Response Elements within the Interleukin-2 Enhancer

1988 • 143 citations

The structure and expression of the murine gene encoding granulocyte-macrophage colony stimulating factor: evidence for utilisation of alternative promoters.

1985 • 129 citations

In vitro activation of the HIV-1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

1987 • 100 citations

Structural analysis of the mouse chromosomal gene encoding interleukin 4 which expresses B cell, T cell and mast cell stimulating activities

1987 • 89 citations

A viral enhancer element specifically active in human haematopoietic cells

1985 • 84 citations

Metal-dependent SV40 viruses containing inducible enhancers from the upstream region of metallothionein genes.

1985 • 84 citations

Promoter Region of Interleukin-2 Gene Undergoes Chromatin Structure Changes and Confers Inducibility on Chloramphenicol Acetyltransferase Gene During Activation of T Cells

1986 • 67 citations

Two regions within the human IL-2 gene promoter are important for inducible IL-2 expression.

1988 • 56 citations

Regulation of IL 2 expression in mitogen-activated murine T lymphocytes

1987 • 14 citations

Hie 5′ region of the human interleukin 4 gene: structure and potential regulatory elements

1988 • 12 citations