Expression of a novel member of estrogen response element-binding nuclear receptors is restricted to the early stages of chorion formation during mouse embryogenesis

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

The induction of differentiation in teratocarcinoma stem cells by retinoic acid

1978 • 1,459 citations

Implantation and the placenta: key pieces of the development puzzle

1994 • 1,362 citations

Generation and Analysis of Interleukin-4 Deficient Mice

1991 • 1,266 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α

1995 • 1,179 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Identification of a retinoic acid responsive element in the retinoic acid receptor & beta;gene

1990 • 1,018 citations

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method.

1988 • 983 citations

Determinants of target gene specificity for steroid/thyroid hormone receptors

1989 • 954 citations

Identification of a new class of steroid hormone receptors

1988 • 845 citations

Reduced levels of hsp90 compromise steroid receptor action in vivo

1990 • 794 citations

Differential Recognition of Target Genes by Nuclear Receptor Monomers, Dimers, and Heterodimers*

1994 • 789 citations

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

1993 • 745 citations

Genetic analysis of RXRα developmental function: Convergence of RXR and RAR signaling pathways in heart and eye morphogenesis

1994 • 684 citations

Evolution of the nuclear receptor gene superfamily.

1992 • 662 citations

The role of heat shock proteins in regulating the function, folding, and trafficking of the glucocorticoid receptor.

1993 • 652 citations

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

1994 • 632 citations

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

1995 • 629 citations

Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor

1990 • 617 citations

Function of retinoic acid receptor γ in the mouse

1993 • 595 citations

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

1995 • 548 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen from a glucocorticoid-responsive element

1989 • 507 citations

Isolation of male embryonal carcinoma cells and their chromosome replication patterns

1982 • 422 citations

Multiple isoforms of the mouse retinoic acid receptor alpha are generated by alternative splicing and differential induction by retinoic acid.

1991 • 395 citations

Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing.

1991 • 390 citations

Cell interactions modulate embryonal carcinoma cell differentiation into parietal or visceral endoderm

1981 • 384 citations

Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression.

1993 • 380 citations

Octamania: The POU factors in murine development

1991 • 373 citations

Two amino acids within the knuckle of the first zinc finger specify DNA response element activation by the glucocorticoid receptor

1989 • 358 citations

Oligodeoxyribonucleotide ligation to single-stranded cDNAs: a new tool for cloning 5′ ends of mRNAs and for constructing cDNA libraries byin vitroamplification

1991 • 312 citations

Retinoic Acid-Induced Neural Differentiation of Embryonal Carcinoma Cells

1983 • 308 citations

FTZ-F1, a Steroid Hormone Receptor-like Protein Implicated in the Activation of fushi tarazu

1991 • 292 citations

Retinoic acid-induced neural differentiation of embryonal carcinoma cells.

1983 • 213 citations

Biology of the Laboratory Mouse.

1941 • 200 citations

Conformational activation of a basic helix-loop-helix protein (MyoD1) by the C-terminal region of murine HSP90 (HSP84).

1992 • 155 citations

The Drosophila retinoid X receptor homolog ultraspiracle functions in both female reproduction and eye morphogenesis

1992 • 149 citations

Competition for Overlapping Sites in the Regulatory Region of the Drosophila Gene Krüppel

1992 • 145 citations

Direct evidence that the glucocorticoid receptor binds to hsp90 at or near the termination of receptor translation in vitro

1989 • 140 citations

A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor.

1994 • 134 citations

Embryonal long terminal repeat-binding protein is a murine homolog of FTZ-F1, a member of the steroid receptor superfamily.

1992 • 130 citations

Glucocorticoid- and progesterone-specific effects are determined by differential expression of the respective hormone receptors

1989 • 129 citations

Cooperativity in transactivation between retinoic acid receptor and TFIID requires an activity analogous to E1A

1992 • 116 citations

A morphological study of the development of the placenta of the rat. I. An outline of the development of the placenta of the white rat

1948 • 112 citations

Estrogen target tissue determines alternative promoter utilization of the human estrogen receptor gene in osteoblasts and tumor cell lines.

1995 • 104 citations

SV40 early-to-late switch involves titration of cellular transcriptional repressors.

1993 • 103 citations

Blastocyst implantation precedes induction of insulin-like growth factor II gene expression in human trophoblasts

1989 • 101 citations

A morphological study of the development of the placenta of the rat. II. An histological and cytological study of the development of the chorioallantoic placenta of the white rat

1948 • 94 citations

Estrogen Formation in the Early Rabbit Embryo

1978 • 94 citations

Structural and functional aspects of basic helix-loop-helix protein folding by heat-shock protein 90.

1994 • 88 citations

Residues in the TATA-binding protein required to mediate a transcriptional response to retinoic acid in EC cells

1993 • 58 citations

Cis-acting sequences affecting the length of the poly(A) head of vaccinia virus late transcripts

1988 • 42 citations

Equilibrium hormone binding to human estrogen receptors in highly diluted cell extracts is non-cooperative and has a K of approximately 10 pM

1994 • 30 citations

Expression of Retinoid X Receptors in P19 Embryonal Carcinoma Cells and Embryonic Stem Cells

1994 • 21 citations

Transcriptional cascades in Drosophila

1993 • 20 citations

Scintillating microtitration plates as platform for determination of [3H]estradiol binding constants for hER-HBD.

1995 • 14 citations