Tyrosine phosphorylation and cytoskeletal tension regulate the release of fibroblast adhesions.

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1992 • 4,454 citations

Models for the Specific Adhesion of Cells to Cells

1978 • 4,159 citations

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

1992 • 1,456 citations

Tyrosine phosphorylation of paxillin and pp125FAK accompanies cell adhesion to extracellular matrix: a role in cytoskeletal assembly.

1992 • 1,330 citations

Fibroblasts, myofibroblasts, and wound contraction

1994 • 1,150 citations

Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton

1993 • 1,124 citations

Paxillin: a new vinculin-binding protein present in focal adhesions.

1990 • 687 citations

Integrins as mechanochemical transducers

1991 • 684 citations

Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src

1987 • 567 citations

[46] Fibronectin: Purification, immunochemical properties, and biological activities

1982 • 542 citations

Isometric contraction by fibroblasts and endothelial cells in tissue culture: a quantitative study

1992 • 456 citations

Rous sarcoma virus-transformed fibroblasts adhere primarily at discrete protrusions of the ventral membrane called podosomes

1985 • 426 citations

A cell free system to study reassembly of the nuclear envelope at the end of mitosis

1986 • 382 citations

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 • 363 citations

Protein kinase C involvement in focal adhesion formation

1992 • 361 citations

Phosphorylation of the fibronectin receptor complex in cells transformed by oncogenes that encode tyrosine kinases.

1986 • 355 citations

Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrils.

1991 • 354 citations

Disassembly of the nucleus in mitotic extracts: Membrane vesicularization, lamin disassembly, and chromosome condensation are independent processes

1987 • 349 citations

Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.

1980 • 334 citations

Myosin I is located at the leading edges of locomoting Dictyostelium amoebae

1989 • 323 citations

Semi-intact cells permeable to macromolecules: Use in reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex

1987 • 321 citations

Association of type 3 protein kinase C with focal contacts in rat embryo fibroblasts.

1989 • 310 citations

Localization of actin and myosin for the study of ameboid movement in Dictyostelium using improved immunofluorescence.

1984 • 306 citations

Bombesin, vasopressin, and endothelin stimulation of tyrosine phosphorylation in Swiss 3T3 cells. Identification of a novel tyrosine kinase as a major substrate.

1992 • 296 citations

Mechanism of retraction of the trailing edge during fibroblast movement.

1981 • 290 citations

Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin

1987 • 280 citations

Altering the cellular mechanical force balance results in integrated changes in cell, cytoskeletal and nuclear shape

1992 • 274 citations

A mechanical function of myosin II in cell motility

1995 • 254 citations

Reversible cyclic AMP-dependent change in distribution of myosin thick filaments in Dictyostelium

1985 • 250 citations

Involvement of myosin light-chain kinase in endothelial cell retraction.

1990 • 249 citations

Dynamics of beta 1 integrin-mediated adhesive contacts in motile fibroblasts.

1992 • 222 citations

Fibronectin receptor exhibits high lateral mobility in embryonic locomoting cells but is immobile in focal contacts and fibrillar streaks in stationary cells.

1988 • 220 citations

Stress relaxation of contracted collagen gels: Disruption of actin filament bundles, release of cell surface fibronectin, and down-regulation of DNA and protein synthesis

1991 • 217 citations

Tyrosine kinase activity, cytoskeletal organization, and motility in human vascular endothelial cells.

1994 • 214 citations

Suppression of vinculin expression by antisense transfection confers changes in cell morphology, motility, and anchorage-dependent growth of 3T3 cells

1993 • 199 citations

Genetics of src: Structure and Functional Organization of a Protein Tyrosine Kinase

1989 • 197 citations

The removal of extracellular fibronectin from areas of cell-substrate contact

1981 • 191 citations

Correlation of myosin light chain phosphorylation with isometric contraction of fibroblasts.

1993 • 186 citations

Focal adhesion sites and the removal of substratum-bound fibronectin.

1986 • 176 citations

The RhoA-dependent assembly of focal adhesions in Swiss 3T3 cells is associated with increased tyrosine phosphorylation and the recruitment of both pp125FAK and protein kinase C-δ to focal adhesions

1994 • 168 citations

In vivo phosphorylation of regulatory light chain of myosin II during mitosis of cultured cells

1994 • 154 citations

Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.

1986 • 149 citations

Relative distribution of actin, myosin I, and myosin II during the wound healing response of fibroblasts.

1993 • 146 citations

Expression of a human T-cell protein-tyrosine-phosphatase in baby hamster kidney cells.

1990 • 132 citations

Perforated MDCK cells support intracellular transport.

1987 • 129 citations

Intermediate filament collapse is an AtP-dependent and actin-dependent process

1989 • 100 citations

Vanadium activates or inhibits receptor and non-receptor protein tyrosine kinases in cell-free experiments, depending on its oxidation state. Possible role of endogenous vanadium in controlling cellular protein tyrosine kinase activity

1994 • 90 citations

Location of actin, myosin, and microtubular structures during directed locomotion of Dictyostelium amebae.

1984 • 90 citations

Reconstitution of transport of vesicular stomatitis virus G protein from the endoplasmic reticulum to the Golgi complex using a cell-free system.

1987 • 77 citations

A fractionated cell-free system for analysis of prophase nuclear disassembly.

1986 • 75 citations

Stress relaxation of fibroblasts activates a cyclic AMP signaling pathway.

1994 • 75 citations

Adhesive multiplicity in the interaction of embryonic fibroblasts and myoblasts with extracellular matrices.

1984 • 74 citations

Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system

1991 • 71 citations

F-actin-binding synthetic heptapeptide having the amino acid sequence around the SH1 cysteinyl residue of myosin.

1987 • 62 citations

Cell‐free systems to study vesicular transport along the secretory and endocytic pathways ¹

1989 • 60 citations

Evidence that intermediate filament reorganization is induced by ATP-dependent contraction of the actomyosin cortex in permeabilized fibroblasts

1991 • 55 citations

Localization of a 215-kDa tyrosine-phosphorylated protein that cross-reacts with tensin antibodies

1992 • 48 citations

Inhibition of endothelial cell retraction by ATP depletion.

1988 • 46 citations

pp60v-src association with the cytoskeleton induces actin reorganization without affecting polymerization status.

1990 • 42 citations

[8] Purification and assay of vinculin, metavinculin, and talin

1986 • 31 citations

Vinculin interaction with permeabilized cells: disruption and reconstitution of a binding site.

1986 • 28 citations

Actin-binding peptides obtained from the C-terminal 24-kDa fragment of porcine aorta smooth muscle myosin subfragment-1 heavy chain.

1993 • 9 citations

Vanadate inhibits both intercellular adhesion and spreading on fibronectin of BHK21 cells and transformed derivatives

1991 • 9 citations

Molecules, Mechanics, and Migration of Cells

1994 • 5 citations

An in vitro model giving access to adhesion plaques

1992 • 4 citations