Environmental enrichment attenuates cognitive deficits, but does not alter neurotrophin gene expression in the hippocampus following lateral fluid percussion brain injury

Place navigation impaired in rats with hippocampal lesions

1982 • 6,277 citations

More hippocampal neurons in adult mice living in an enriched environment

1997 • 3,476 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

Neural consequences of enviromental enrichment

2000 • 2,376 citations

Traumatic brain injury

2000 • 2,255 citations

Traumatic brain injury in the rat: Characterization of a lateral fluid-percussion model

1989 • 1,126 citations

Psychobiology of plasticity: effects of training and experience on brain and behavior

1996 • 953 citations

Enriched environment increases neurogenesis in the adult rat dentate gyrus and improves spatial memory

1999 • 840 citations

Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family

1990 • 817 citations

trkB, a neural receptor protein-tyrosine kinase: evidence for a full-length and two truncated receptors.

1991 • 785 citations

Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective

1999 • 733 citations

BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: Temporal patterns of induction distinct from NGF

1991 • 699 citations

Selective vulnerability of dentate hilar neurons following traumatic brain injury: a potential mechanistic link between head trauma and disorders of the hippocampus

1992 • 680 citations

Opposing Roles for Endogenous BDNF and NT-3 in Regulating Cortical Dendritic Growth

1997 • 578 citations

Long-Term Environmental Enrichment Leads to Regional Increases in Neurotrophin Levels in Rat Brain

2000 • 538 citations

Increased expression of brain-derived neurotrophic factor mRNA in rat hippocampus is associated with improved spatial memory and enriched environment

1992 • 386 citations

Mild Experimental Brain Injury in the Rat Induces Cognitive Deficits Associated with Regional Neuronal Loss in the Hippocampus

1993 • 359 citations

Outcome after severe head injury

1987 • 338 citations

Environment Influences Functional Outcome of Cerebral Infarction in Rats

1995 • 322 citations

Distribution of Brain‐Derived Neurotrophic Factor in Rats and Its Changes with Development in the Brain

1997 • 291 citations

Dopaminergic neurons in rat ventral midbrain express brain‐derived neurotrophic factor and neurotrophin‐3 mRNAs

1994 • 290 citations

Temporal and spatial characterization of neuronal injury following lateral fluid-percussion brain injury in the rat

1996 • 289 citations

Developmental and mature expression of full-length and truncated TrkB, receptors in the rat forebrain

1996 • 281 citations

Neurotrophins and hippocampal synaptic transmission and plasticity

1999 • 253 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 228 citations

Regulation of neurotrophin receptor expression during embryonic and postnatal development

1994 • 208 citations

Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?

1998 • 205 citations

Environmental Enrichment and Cortical Injury: Behavioral and Anatomical Consequences of Frontal Cortex Lesions

1991 • 204 citations

Trophic regulation of synaptic plasticity

1999 • 187 citations

BDNF Protects against Spatial Memory Deficits Following Neonatal Hypoxia-Ischemia

2000 • 187 citations

Environmental enrichment results in higher levels of nerve growth factor mRNA in the rat visual cortex and hippocampus

1998 • 184 citations

Exposure to Environmental Complexity Promotes Recovery of Cognitive Function after Traumatic Brain Injury

1996 • 169 citations

Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma

1997 • 137 citations

Effect of neonatal cortical lesions and early environmental factors on adult rat behavior.

1964 • 106 citations

Increased expression of brain-derived neurotrophic factor but not neurotrophin-3 mRNA in rat brain after cortical impact injury

1996 • 103 citations

Regional brain-derived neurotrophic factor mRNA and protein levels following transient forebrain ischemia in the rat

1996 • 101 citations

Pathology: Implications for the Physical Therapist

1998 • 96 citations

Effects of differential environments on recovery from neonatal brain lesions, measured by problem-solving scores and brain dimensions

1976 • 87 citations

Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury

1992 • 81 citations

Brain-derived neurotrophic factor administration after traumatic brain injury in the rat does not protect against behavioral or histological deficits

2000 • 80 citations

Cellular Localization of NGF and NT-3 mRNAs in Postnatal Rat Forebrain

1994 • 77 citations

Regulation of brain neurctrophin expression by physiological activity

1992 • 77 citations

Overexpression of Nerve Growth Factor in Skin Increases Sensory Neuron Size and Modulates Trk Receptor Expression

1997 • 70 citations

Environmental influence on brain-derived neurotrophic factor messenger RNA expression after middle cerebral artery occlusion in spontaneously hypertensive rats

2000 • 61 citations

Severe Accidental Head Injury

1979 • 60 citations

Postsurgical enrichment aids adult hemidecorticate rats on a spatial navigation task

1984 • 58 citations

Effects of Exercise Following Lateral Fluid Percussion Brain Injury in Rats

1998 • 51 citations

Effects of Post-Operative Environment on Recovery from Dorsal Hippocampal Lesions in Young Rats: Tests of Spatial Memory and Motor Transfer

1980 • 46 citations

Severe accidental head injury : an assessment of long-term prognosis

1979 • 36 citations

In situ hybridization approaches to the study of the nervous system

1997 • 22 citations

Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury

2000 • 19 citations